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Protein Overview: Caf1-105-PA

General Information:
Name(s) found: Caf1-105-PA / FBpp0087402 [FlyBase]
Description(s) found:
Found 20 descriptions.
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  • The gene Caf1-105 is referred to in FlyBase by the symbol Dmel\Caf1-105 (CG12892, FBgn0033526). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:6353518..6355994. It has the cytological map location 47A9. It is reported to have molecular function</span>: DNA binding. Based on sequence similarity, it is predicted to be involved in the biological process</span>: chromatin assembly or disassembly. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 747 amino acids

    Gene Ontology:
    Cellular Component: chromatin assembly complex [ISS][NAS]
    Biological Process: chromatin assembly or disassembly [ISS]
    nucleosome assembly [NAS]
    Molecular Function: DNA binding [NAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKCKIPEISW HNRDPVLSVD IQQNGLGLRS PTICRLASGG SDAHVLIWYV NRSDDAEGVD  60
   61 VELAADLSRH QRAVNAVRWS PNGELLASGD DESVVFIWKQ KADHEVVNIV DADGCSEQDK 120
  121 EVWLTLKVLR GHREDIYDLS WAPNSQFLVS GSVDNTAMLW DVHSGKSLAI LDDHKGYVQG 180
  181 VAWDPCNQYI ATMSTDRQMR IFDANTKRVL HRVSKCVLPV KEDHEMHGKS MRLYQDGTLQ 240
  241 TFFRRLCFTP DGKLLLTPSG ITDYDGVVKP INTSYGFSRH DLSKPAFVLP FPKEYAVAVR 300
  301 CSPVLYRLRP YNAEKNPPII SLPYRMIYAV ATKNAVFFYD TQQPVPFAIV SNIHYSRLTD 360
  361 LAWSSDGTVL IVSSTDGYCS LITFEPTELG DCYEDMETVL SVVLKSSENA TVLKKKRQKL 420
  421 RKVSLDEPRK PLQEKSKPNT IRRASEAGIT EVGEPELDAE NDSSTHSVSS NKTNSPKTKA 480
  481 SEEEKPTPIA IRRSPRKNST APMPIAIRRA PRKPEDKGNS ESSKPKDEME VTHTKTTQVQ 540
  541 KTVASPVKRK VSTEAVPPAE TSQPALAVIP VFEKEIISSD DKFESPEKKS RPATPIQVRR 600
  601 QPRTPGSSSQ FNLTPKSQPA KQATPIAVRR TPRVLIEMPV NSPVVPMEEA MDAWPLDESI 660
  661 TPLPATKKDS RKPLPETVKT ETKPAVIEAS EATCERTEDI RLVYEDTQEE TPKNPTESGP 720
  721 STPNNKTPRR VSLRTISTPK SKKKLLE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..429] PSI-BLAST 72.39794 PAF-AH Holoenzyme: Lis1/Alfa2
    2 View Details [430..523] deduced N/A No confident structure predictions are available.
    3 View Details [524..747] MSA 8.130997 View MSA. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • general RNA polymerase II transcription factor activity
    		•  2.79445416141967 bayes_pls_golite062009
  • binding
    		•  2.42570478946173 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.3610959773142 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.30918780727915 bayes_pls_golite062009
  • transcription repressor activity
    		•  2.29049708962212 bayes_pls_golite062009
  • dynein binding
    		•  1.74989209255308 bayes_pls_golite062009
  • DNA binding
    		•  1.71685536470455 bayes_pls_golite062009
  • transcription corepressor activity
    		•  1.41752877005447 bayes_pls_golite062009
  • protein binding
    		•  1.21879977456466 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  1.19593750149343 bayes_pls_golite062009
  • transcription factor activity
    		•  1.08768505897883 bayes_pls_golite062009
    		• 0.88172763425403 bayes_pls_golite062009
  • histone binding
    		•  0.685319917508843 bayes_pls_golite062009
  • DNA-dependent ATPase activity
    		•  0.625780732991652 bayes_pls_golite062009
  • actin binding
    		•  0.529861581509437 bayes_pls_golite062009
  • transcription factor binding
    		•  0.489473003915035 bayes_pls_golite062009
  • snoRNA binding
    		•  0.347797037104681 bayes_pls_golite062009
  • transcription cofactor activity
    		•  0.30761651528651 bayes_pls_golite062009
  • DNA helicase activity
    		•  0.220747580531792 bayes_pls_golite062009
  • structural molecule activity
    		•  0.0936365746095786 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle