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Protein Overview: dap-PA

General Information:
Name(s) found: dap-PA / FBpp0087553 [FlyBase]
Description(s) found:
Found 22 descriptions.
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  • The gene dacapo is referred to in FlyBase by the symbol Dmel\dap (CG1772, FBgn0010316). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:5599828..5603607. It has the cytological map location 46B1. There is experimental evidence that it has the molecular function</span>: cyclin-dependent protein kinase inhibitor activity. There is experimental evidence that it is involved in the biological process</span>: germarium-derived oocyte fate determination; histoblast morphogenesis; G1 phase; negative regulation of S phase of mitotic cell cycle; negative regulation of protein amino acid dephosphorylation; sensory organ precursor cell division. 32 alleles are reported. The phenotypes of these alleles are annotated with 23 unique terms, many of which group under: peripheral nervous system; nervous system; organ system; adult segment; adult mesothoracic segment; egg; external compound sense organ; embryonic/larval tracheal system; embryonic nervous system; imaginal precursor. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 245 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDA]
    Biological Process: cell cycle arrest [IEA]
    regulation of protein kinase activity [TAS]
    negative regulation of S phase of mitotic cell cycle [IMP]
    germarium-derived oocyte fate determination [IMP]
    negative regulation of cell cycle [TAS]
    histoblast morphogenesis [IMP]
    sensory organ development [NAS]
    open tracheal system development [TAS]
    regulation of cyclin-dependent protein kinase activity [TAS]
    oogenesis [TAS]
    sensory organ precursor cell division [IMP]
    G1/S transition of mitotic cell cycle [NAS]
    G1 phase [IMP]
    negative regulation of protein amino acid dephosphorylation [IDA]
    Molecular Function: cyclin-dependent protein kinase inhibitor activity [IDA][ISS][NAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVSARVLNPV MISEFCKMSS SPAVSRNLAC GRQLNRIKRD LFGSSKSAEG TANKTPFNSE  60
   61 LERHQELATQ KWGFDFRAGC PLAEKSPYIW ERVSFQESSF APEMYTLTRA AHVRPSADAS 120
  121 PSDMDILVNE RSERENFGSN LVNSSLESNT DNESCYDSQD ESLAMRLSSS STTSTSSIVL 180
  181 RKRQPKITEF MKERKRLAQA PKKLSPAKRM RTSSPSSSAT SSSSSSGGFG LGAHFGAMLK 240
  241 RPRHN

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..145] FFAS03 4.02 P27(KIP1) fragment 22-106
    2 View Details [146..245] deduced N/A No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.41

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle