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Protein Overview: Pgi-PC, Pgi-PA, ...

General Information:
Name(s) found: Pgi-PC / FBpp0087762 [FlyBase]
Pgi-PB / FBpp0087761 [FlyBase]
Pgi-PA / FBpp0087760 [FlyBase]
Description(s) found:
Found 63 descriptions.
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  • The gene Phosphoglucose isomerase is referred to in FlyBase by the symbol Dmel\Pgi (CG8251, FBgn0003074). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:4798407..4801631. It has the cytological map location 44F6. There is experimental evidence that it has the molecular function</span>: glucose-6-phosphate isomerase activity. It is reported to be involved in the biological process</span>: gluconeogenesis; glycolysis. 20 alleles are reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides. [FlyBase]
  • The gene Phosphoglucose isomerase is referred to in FlyBase by the symbol Dmel\Pgi (CG8251, FBgn0003074). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:4798407..4801631. It has the cytological map location 44F6. There is experimental evidence that it has the molecular function</span>: glucose-6-phosphate isomerase activity. It is reported to be involved in the biological process</span>: gluconeogenesis; glycolysis. 20 alleles are reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides. [FlyBase]
  • The gene Phosphoglucose isomerase is referred to in FlyBase by the symbol Dmel\Pgi (CG8251, FBgn0003074). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:4798407..4801631. It has the cytological map location 44F6. There is experimental evidence that it has the molecular function</span>: glucose-6-phosphate isomerase activity. It is reported to be involved in the biological process</span>: gluconeogenesis; glycolysis. 20 alleles are reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 558 amino acids

    Gene Ontology:
    Cellular Component: lipid particle [IDA]
    cytoplasm [NAS]
    Biological Process: gluconeogenesis [IEA][NAS]
    glycolysis [IEA][NAS]
    Molecular Function: glucose-6-phosphate isomerase activity [IMP][NAS]
    phosphogluconate dehydrogenase (decarboxylating) activity [ISS][TAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAGPLPPLNQ EAAFQKLQEY YDSKGKDLNI KDLFVKDSKR FSKYSLRLHT QNDGEILLDY  60
   61 SKNRINDEVW DLLLTLAKVR RVNAARDAMF SGQHINITEN RAVLHTALRN RGTDPVLVDD 120
  121 KDVMPDVRAE LAHMKEFTNM VISGVWRGCT GKQITDVVNI GIGGSDLGPL MVTEALKPYG 180
  181 KGLHSHFVSN IDGTHLAEVL KKVNYETTLF IVASKTFTTQ ETITNATSAK TWLLEHSKEP 240
  241 ESVAKHFVAL STNKEKVTEF GIDSTNMFGF WDWVGGRYSL WSAIGLSICL SIGFENFEQL 300
  301 LDGAHFMDNH FKTTPFEKNA PVILALLGVW YSNFFKAETH ALLPYDQYLH RFAAYFQQGD 360
  361 MESNGKFVSK SGKPVKYSTG PIVWGEPGTN GQHAFYQLIH QGTRLIPCDF IAPAQTHNPI 420
  421 AGGKHHKILL SNFLAQTEAL MAGKTVDEAR TELSKAGLCG NELDNLLPHK VFVGNRPTNS 480
  481 IVVKKVSPFT LGALIALYEH KIFVQGIIWD INSFDQWGVE LGKQLAKAIE PELDHCNEVS 540
  541 THDSSTNGLI NFIKANWK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..558] PSI-BLAST 1000.0 Phosphoglucose isomerase, PGI

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • glucose-6-phosphate isomerase activity
    		•  3.62042557708076 bayes_pls_golite062009
  • intramolecular oxidoreductase activity
    		•  2.12646274924126 bayes_pls_golite062009
  • intramolecular oxidoreductase activity, interconverting aldoses and ketoses
    		•  1.62962150339138 bayes_pls_golite062009
  • catalytic activity
    		•  1.5278037255884 bayes_pls_golite062009
  • sugar binding
    		•  1.40175307923331 bayes_pls_golite062009
  • glutamine-fructose-6-phosphate transaminase (isomerizing) activity
    		•  1.11549102314657 bayes_pls_golite062009
  • binding
    		•  1.0425673151455 bayes_pls_golite062009
  • D-sedoheptulose 7-phosphate isomerase activity
    		•  0.969046173332955 bayes_pls_golite062009
  • isomerase activity
    		•  0.875614547872629 bayes_pls_golite062009
  • carbohydrate binding
    		•  0.5730945843207 bayes_pls_golite062009
  • protein binding
    		•  0.152745336606766 bayes_pls_golite062009
  • transferase activity
    		•  0.0523744832826621 bayes_pls_golite062009
  • transferase activity, transferring nitrogenous groups
    		•  0.0239994594084577 bayes_pls_golite062009
  • transaminase activity
    		•  0.00531525548288503 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.87

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle