Protein Overview: grp-PA, grp-PC, ...

General Information:
Name(s) found:	grp-PA / FBpp0080443 [FlyBase] grp-PC / FBpp0080442 [FlyBase] grp-PB / FBpp0080441 [FlyBase]
Description(s) found: Found 50 descriptions. SHOW ALL	The gene grapes is referred to in FlyBase by the symbol Dmel\grp (CG17161, FBgn0261278). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:16680046..16699930. It has the cytological map location 36A10-36A11. Based on sequence similarity, it is predicted to have molecular function</span>: protein kinase activity; protein serine/threonine kinase activity. There is experimental evidence that it is involved in the biological process</span>: female meiosis chromosome segregation; centrosome separation; cell cycle arrest; regulation of syncytial blastoderm mitotic cell cycle; spindle assembly; cell cycle; DNA damage checkpoint. 95 alleles are reported. The phenotypes of these alleles are annotated with 11 unique terms, many of which group under: peripheral nervous system; syncytial blastoderm embryo; nervous system; cleavage stage embryo; blastoderm embryo; organ system; intracellular organelle part; eo support cell; cytoskeletal part; cytoplasmic part; cell part; spindle; midbody; sensillum; external compound sense organ. It has 4 annotated transcripts and 4 annotated polypeptides. [FlyBase] The gene grapes is referred to in FlyBase by the symbol Dmel\grp (CG17161, FBgn0261278). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:16680046..16699930. It has the cytological map location 36A10-36A11. Based on sequence similarity, it is predicted to have molecular function</span>: protein kinase activity; protein serine/threonine kinase activity. There is experimental evidence that it is involved in the biological process</span>: female meiosis chromosome segregation; centrosome separation; cell cycle arrest; regulation of syncytial blastoderm mitotic cell cycle; spindle assembly; cell cycle; DNA damage checkpoint. 95 alleles are reported. The phenotypes of these alleles are annotated with 11 unique terms, many of which group under: peripheral nervous system; syncytial blastoderm embryo; nervous system; cleavage stage embryo; blastoderm embryo; organ system; intracellular organelle part; eo support cell; cytoskeletal part; cytoplasmic part; cell part; spindle; midbody; sensillum; external compound sense organ. It has 4 annotated transcripts and 4 annotated polypeptides. [FlyBase] The gene grapes is referred to in FlyBase by the symbol Dmel\grp (CG17161, FBgn0261278). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:16680046..16699930. It has the cytological map location 36A10-36A11. Based on sequence similarity, it is predicted to have molecular function</span>: protein kinase activity; protein serine/threonine kinase activity. There is experimental evidence that it is involved in the biological process</span>: female meiosis chromosome segregation; centrosome separation; cell cycle arrest; regulation of syncytial blastoderm mitotic cell cycle; spindle assembly; cell cycle; DNA damage checkpoint. 95 alleles are reported. The phenotypes of these alleles are annotated with 11 unique terms, many of which group under: peripheral nervous system; syncytial blastoderm embryo; nervous system; cleavage stage embryo; blastoderm embryo; organ system; intracellular organelle part; eo support cell; cytoskeletal part; cytoplasmic part; cell part; spindle; midbody; sensillum; external compound sense organ. It has 4 annotated transcripts and 4 annotated polypeptides. [FlyBase]
Organism:	Drosophila melanogaster
Length:	512 amino acids
Gene Ontology:
Cellular Component:	nucleus [IDA]
Biological Process:	cell cycle arrest [IMP] mitotic cell cycle checkpoint [TAS] regulation of proteolysis [TAS] response to radiation [TAS] imaginal disc development [TAS] protein amino acid phosphorylation [ISS][NAS] regulation of syncytial blastoderm mitotic cell cycle [IMP][TAS] cellularization [TAS] cell cycle [IMP] DNA damage checkpoint [IMP][ISS][TAS] spindle assembly [IMP] centrosome separation [IMP] cell cycle checkpoint [ISS][TAS] embryonic development via the syncytial blastoderm [TAS] female meiosis chromosome segregation [IMP]
Molecular Function:	ATP binding [IEA] protein kinase activity [ISS][NAS] protein serine/threonine kinase activity [IEA][ISS][TAS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAATLTEAGT GPAATREFVE GWTLAQTLGE GAYGEVKLLI NRQTGEAVAM KMVDLKKHPD  60
   61 AANSVRKEVC IQKMLQDKHI LRFFGKRSQG SVEYIFLEYA AGGELFDRIE PDVGMPQHEA 120
  121 QRYFTQLLSG LNYLHQRGIA HRDLKPENLL LDEHDNVKIS DFGMATMFRC KGKERLLDKR 180
  181 CGTLPYVAPE VLQKAYHAQP ADLWSCGVIL VTMLAGELPW DQPSTNCTEF TNWRDNDHWQ 240
  241 LQTPWSKLDT LAISLLRKLL ATSPGTRLTL EKTLDHKWCN MQFADNERSY DLVDSAAALE 300
  301 ICSPKAKRQR LQSSAHLSNG LDDSISRNYC SQPMPTMRSD DDFNVRLGSG RSKEDGGDRQ 360
  361 TLAQEARLSY SFSQPALLDD LLLATQMNQT QNASQNYFQR LVRRMTRFFV TTRWDDTIKR 420
  421 LVGTIERLGG YTCKFGDDGV VTVSTVDRNK LRLVFKAHII EMDGKILVDC RLSKGCGLEF 480
  481 KRRFIKIKNA LEDIVLKGPT TWPIAIATNS VP

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.97

Protein Overview: grp-PA, grp-PC, ...

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: