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Any process that modulates the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein. Any process that modulates the frequency, rate or extent of the proteolytic cleavage of transmembrane proteins and release of their ectodomain (extracellular domain). Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a protein. Any process that modulates the frequency, rate, or extent of proteolysis associated with antigen processing and presentation. Any process that modulates the rate, frequency, or extent of the chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds that is mediated by the proteasome. The chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with the hydrolysis of peptide bonds. Any process that modulates the frequency, rate or extent of the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome. Any process that activates or increases the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. The chemical reactions and pathways involving a specific protein, rather than of proteins in general. Includes protein modification. Any process that stops, prevents or reduces the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism involving those compounds formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: regulation of proteolysis
Acc: GO:0030162
Aspect: Biological Process
Desc: Any process that modulates the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein.
Synonyms:
  • regulation of peptidolysis
Proteins in PDR annotated with:
   This term: 65 [Search]
   Term or descendants: 197 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0030162 - regulation of proteolysis (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle