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Protein Overview: Su(H)-PA, FBpp03...

General Information:
Name(s) found: FBpp0310273 [FlyBase]
Su(H)-PA / FBpp0080261 [FlyBase]
Description(s) found:
Found 34 descriptions.
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  • type=protein; loc=2L:join(15039937..15040320,15041095..15041975,15042034..15042241,15042307..15042618); ID=FBpp0310273; name=Su(H)-PB; parent=FBgn0004837,FBtr0343685; dbxref=FlyBase:FBpp0310273,FlyBase_Annotation_IDs:CG3497-PB; MD5=4bacd3265a70c13636746d6526a31493; length=594; release=r5.56; species=Dmel; [FlyBase]
  • The gene Suppressor of Hairless is referred to in FlyBase by the symbol Dmel\Su(H) (CG3497, FBgn0004837). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:15039496..15043335. It has the cytological map location 35B8. There is experimental evidence that it has the molecular function</span>: protein binding; sequence-specific DNA binding; specific transcriptional repressor activity; DNA binding. There is experimental evidence that it is involved in the biological process</span>: sensory organ precursor cell fate determination; crystal cell differentiation; wing disc dorsal/ventral pattern formation; Notch signaling pathway; positive regulation of S phase of mitotic cell cycle. 86 alleles are reported. The phenotypes of these alleles are annotated with 38 unique terms, many of which group under: organ system; adult segment; peripheral nervous system; adult mesothoracic segment; nervous system; primordium; late extended germ band embryo; imaginal precursor; embryonic nervous system; embryonic hindgut; ectoderm derivative; external compound sense organ. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 594 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDA][ISS][TAS]
    cytoplasm [IDA]
    protein complex [IPI]
    Biological Process: [NOT]dorsal/ventral lineage restriction, imaginal disc [NAS]
    hemopoiesis [TAS]
    negative regulation of compound eye cone cell fate specification [TAS]
    regulation of transcription, DNA-dependent [IEA]
    asymmetric cell division [TAS]
    positive regulation of transcription from RNA polymerase II promoter [TAS]
    regulation of transcription [IEA]
    crystal cell differentiation [IMP]
    Notch signaling pathway [IGI][IMP][NAS][TAS]
    negative regulation of transcription, DNA-dependent [TAS]
    positive regulation of transcription, DNA-dependent [TAS]
    positive regulation of S phase of mitotic cell cycle [IMP]
    sensory organ precursor cell fate determination [IMP]
    lateral inhibition [TAS]
    wing disc dorsal/ventral pattern formation [IGI]
    cell fate determination [TAS]
    Molecular Function: DNA binding [IDA][NAS][TAS]
    transcription factor activity [IEA]
    protein binding [IPI][TAS]
    RNA polymerase II transcription factor activity [ISS]
    sequence-specific DNA binding [IDA]
    transcription activator activity [TAS]
    transcription repressor activity [TAS]
    specific transcriptional repressor activity [IMP]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKSYSQFNLN AAAPPAIAYE TTVVNPNGSP LDPHQQQQQQ SQDMPHFGLP GPQPPSSQQQ  60
   61 QQQLQVHHQQ QQQQQQQQQQ QQHQQQMQMS LLPGPYRPHI EEKKLTRDAM EKYMRERNDM 120
  121 VIVILHAKVA QKSYGNEKRF FCPPPCIYLF GSGWRRRYEE MLQQGEGEQG AQLCAFIGIG 180
  181 SSDQDMQQLD LNGKQYCAAK TLFISDSDKR KHFMLSVKMF YGNGHDIGVF NSKRIKVISK 240
  241 PSKKKQSLKN ADLCIASGTN VALFNRLRSQ TVSTRYLHVE NGHFHASSTQ WGAFTIHLLD 300
  301 DNESESEEFQ VRDGYIHYGA TVKLVCSVTG MALPRLIIRK VDKQMALLEA DDPVSQLHKC 360
  361 AFYMKDTDRM YLCLSQEKII QFQATPCPKE PNKEMINDGA CWTIISTDKA EYQFYEGMGP 420
  421 VASPVTPVPI VNSLNLNGGG DVAMLELSGD NFTPHLQVWF GDVEAETMYR CTETLLCVVP 480
  481 EISQFRGEWL WVRQPTQVPI SLVRNDGIIY ATGLTFTYTP EPGPRPHCNT QAEDVMRARQ 540
  541 NNNNNNITSI SNNNNSNNAG SPAAGGGLQQ QQQQHQALPS ISEVQWNSHG SGLS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.88

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle