Protein Overview: bun-PB

General Information:
Name(s) found:	bun-PB / FBpp0288931 [FlyBase]
Description(s) found: Found 22 descriptions. SHOW ALL	The gene bunched is referred to in FlyBase by the symbol Dmel\bun (CG42281, FBgn0259176). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:12456577..12546630. It has the cytological map location 33E5-33E9. Based on sequence similarity, it is predicted to have molecular function</span>: protein homodimerization activity. There is experimental evidence for 13 unique biological process</span> terms, many of which group under: regulation of biological process; anatomical structure development; reproductive process in a multicellular organism; regulation of developmental process; programmed cell death; ovarian follicle cell development; positive regulation of biological process; positive regulation of cell proliferation; regionalization; regulation of anatomical structure size; gland morphogenesis; regulation of apoptosis; negative regulation of Notch signaling pathway. 139 alleles are reported. The phenotypes of these alleles are annotated with 15 unique terms, many of which group under: external compound sense organ; organ system; peripheral nervous system; adult segment; nervous system; female germline cyst; egg; chorion; thoracic segment; adult mesothoracic segment. It has 8 annotated transcripts and 8 annotated polypeptides. [FlyBase]
Organism:	Drosophila melanogaster
Length:	219 amino acids
Gene Ontology:
Cellular Component:	nucleus [NAS] cytoplasm [IDA][NAS]
Biological Process:	segmentation [IMP] ovarian follicle cell migration [IMP] positive regulation of cell proliferation [IMP] negative regulation of cell fate specification [IMP] dorsal appendage formation [IMP][NAS] peripheral nervous system development [NAS] regulation of transcription, DNA-dependent [IEA] salivary gland cell autophagic cell death [IEP] decapentaplegic receptor signaling pathway [IGI] chorion-containing eggshell formation [IMP] negative regulation of Notch signaling pathway [IMP] compound eye development [NAS] compound eye photoreceptor cell differentiation [IMP] positive regulation of cell growth [IMP] oogenesis [NAS] ovarian follicle cell development [TAS] autophagic cell death [IEP] negative regulation of apoptosis [IMP] cell fate determination [NAS]
Molecular Function:	transcription factor activity [IEA] protein homodimerization activity [ISS] RNA polymerase II transcription factor activity [NAS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKTETGSNNN NTTVVNMDFD MYPSISGKQQ DPVREVVMKY IDYFLPDASG TSAVAIDNKI  60
   61 EQAMDLVKSH LMIAVREEVE VLKERISELM DKINKLELEN SILKSNIPQE TLQQLQLQLQ 120
  121 LAAPPATPAI QAAPAVQSVV APAAAGQAVQ QQAAGAVAVT GVATSPASAV VPTSIPNGSA 180
  181 ENGSSAVESA AVSVEQQVQQ VTSAAAAAAS VVTANGPMS

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.95

Protein Overview: bun-PB

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: