Protein Overview: bun-PA

General Information:
Name(s) found:	bun-PA / FBpp0289748 [FlyBase]
Description(s) found: Found 23 descriptions. SHOW ALL	The gene bunched is referred to in FlyBase by the symbol Dmel\bun (CG42281, FBgn0259176). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:12456577..12546630. It has the cytological map location 33E5-33E9. Based on sequence similarity, it is predicted to have molecular function</span>: protein homodimerization activity. There is experimental evidence for 13 unique biological process</span> terms, many of which group under: regulation of biological process; anatomical structure development; reproductive process in a multicellular organism; regulation of developmental process; programmed cell death; ovarian follicle cell development; positive regulation of biological process; positive regulation of cell proliferation; regionalization; regulation of anatomical structure size; gland morphogenesis; regulation of apoptosis; negative regulation of Notch signaling pathway. 139 alleles are reported. The phenotypes of these alleles are annotated with 15 unique terms, many of which group under: external compound sense organ; organ system; peripheral nervous system; adult segment; nervous system; female germline cyst; egg; chorion; thoracic segment; adult mesothoracic segment. It has 8 annotated transcripts and 8 annotated polypeptides. [FlyBase]
Organism:	Drosophila melanogaster
Length:	1206 amino acids
Gene Ontology:
Cellular Component:	nucleus [NAS] cytoplasm [IDA][NAS]
Biological Process:	segmentation [IMP] ovarian follicle cell migration [IMP] positive regulation of cell proliferation [IMP] negative regulation of cell fate specification [IMP] dorsal appendage formation [IMP][NAS] peripheral nervous system development [NAS] regulation of transcription, DNA-dependent [IEA] salivary gland cell autophagic cell death [IEP] decapentaplegic receptor signaling pathway [IGI] chorion-containing eggshell formation [IMP] negative regulation of Notch signaling pathway [IMP] compound eye development [NAS] compound eye photoreceptor cell differentiation [IMP] positive regulation of cell growth [IMP] oogenesis [NAS] ovarian follicle cell development [TAS] autophagic cell death [IEP] negative regulation of apoptosis [IMP] cell fate determination [NAS]
Molecular Function:	transcription factor activity [IEA] protein homodimerization activity [ISS] RNA polymerase II transcription factor activity [NAS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAENQSAASK DSGHQQQHQQ QQQQQHQQHQ QPLATTSVTA ASTTSVLANQ SPTNSQASSP  60
   61 ENSQEALPLL RRQQSAAAAT VAAAAATVAA TTSGTSQQQQ QQHRNSISNM FDRTVNAKFK 120
  121 PASSNAGPGN NPVRRNSMLT PSRGVTIGGT GGNIRKLTKV SSLTSNHHFA VCYPPSNIYQ 180
  181 NSNNAGSNSA LQRTTSESLR LNMMSRVAAG ATPTTVSRAS SNSSLATSTS TSLAPKSSSS 240
  241 SGGSNSTPQQ QQQQLVSSNN SSSSSNNSFT KASSPNNNGA RSVGGAATSA ATGTTAAAGS 300
  301 HHHQPHHHHH HHHHHHQHHN HQQQQQQQTS LSQGHASLTV AGGSASAGGG GGGGSGSSSG 360
  361 TAAGGTNRKP KTTSSFEITS VTVGHPKLNA AGDTGDESAD DLDESHTDDN SRITDLENET 420
  421 PSMSEDTFSK EEVYYANNAL STNAPVIPTS SQYGLVVVDP IAPSLGQTIQ NVQVNVSDNI 480
  481 INVVSGAVTP GGTKKKDDIK ETQHRSERFK VVKIESTEPF KRGRWMCMDY LDHSSVGNGG 540
  541 NNNEKTGSST SEAHAATTDG GAAGVGAGSE APAHKTTQSM ILPPTQKLNE NHLEANSTDA 600
  601 NWNYAEQQQQ QQQQQQQQQT IVGNALTKTL PVALRNVSRS SSVTRSPNAT VEFLSPNLLA 660
  661 QQQQQQQQLF DSVNANAASS PNPAGDPNNM DYARTAAMQL HQTLQQLKQR EDAMDVPPGA 720
  721 GGYANYQNGG DSAVGAASNN NSAAAATGES QLSTSYVEQQ QQQQQPLSPA PLTPQAAPTF 780
  781 AAVAAGQSPN FQLEQQQQQQ QATSQIDGIV PQPFNPQQQQ QQTPQQSTAQ QAAAAANATS 840
  841 AVTAPPPQQT SNTSNAAVTT GQGQTMPLLS HMTSYEQQQP NLGAAAAAAA AGGTAATSVA 900
  901 APQAIPTLQL QSAPSTIADP QQLMVPQQQQ QQQHQEEQQQ QPQQQQQPLP PANIASASAN 960
  961 NSNLNLTNTN VVATGEATTN ALTLTDEQAT AALAAAFATG AAAAATGATS AAAATQQQIQ1020
 1021 QLQQQPNAES ETESASGTSA VAIDNKIEQA MDLVKSHLMI AVREEVEVLK ERISELMDKI1080
 1081 NKLELENSIL KSNIPQETLQ QLQLQLQLAA PPATPAIQAA PAVQSVVAPA AAGQAVQQQA1140
 1141 AGAVAVTGVA TSPASAVVPT SIPNGSAENG SSAVESAAVS VEQQVQQVTS AAAAAASVVT1200
 1201 ANGPMS

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: bun-PA

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: