Protein Overview: aret-PA, aret-PE

General Information:
Name(s) found:	aret-PE / FBpp0289794 [FlyBase] aret-PA / FBpp0079927 [FlyBase]
Description(s) found: Found 29 descriptions. SHOW ALL	The gene arrest is referred to in FlyBase by the symbol Dmel\aret (CG31762, FBgn0000114). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:12205843..12312795. It has the cytological map location 33D3-33D5. There is experimental evidence that it has the molecular function</span>: protein binding; RNA binding; mRNA 3'-UTR binding. There is experimental evidence that it is involved in the biological process</span>: inter-male aggressive behavior; oogenesis; negative regulation of oskar mRNA translation; spermatid development; positive regulation of exit from mitosis; germ cell development; negative regulation of translation; regulation of alternative nuclear mRNA splicing, via spliceosome. 34 alleles are reported. The phenotypes of these alleles are annotated with 12 unique terms, many of which group under: organ system; female germline cyst; anatomical structure; germline cell; egg; germarium; cell part; chorion; chorion; spectrosome. It has 5 annotated transcripts and 5 annotated polypeptides. [FlyBase] The gene arrest is referred to in FlyBase by the symbol Dmel\aret (CG31762, FBgn0000114). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:12205843..12312795. It has the cytological map location 33D3-33D5. There is experimental evidence that it has the molecular function</span>: protein binding; RNA binding; mRNA 3'-UTR binding. There is experimental evidence that it is involved in the biological process</span>: inter-male aggressive behavior; oogenesis; negative regulation of oskar mRNA translation; spermatid development; positive regulation of exit from mitosis; germ cell development; negative regulation of translation; regulation of alternative nuclear mRNA splicing, via spliceosome. 34 alleles are reported. The phenotypes of these alleles are annotated with 12 unique terms, many of which group under: organ system; female germline cyst; anatomical structure; germline cell; egg; germarium; cell part; chorion; chorion; spectrosome. It has 5 annotated transcripts and 5 annotated polypeptides. [FlyBase]
Organism:	Drosophila melanogaster
Length:	604 amino acids
Gene Ontology:
Cellular Component:	nucleus [IC] P granule [IDA]
Biological Process:	negative regulation of oskar mRNA translation [IDA][NAS][TAS] germ cell development [IMP] positive regulation of exit from mitosis [IMP] germarium-derived female germ-line cyst formation [TAS] oogenesis [IMP] spermatid development [IMP] regulation of alternative nuclear mRNA splicing, via spliceosome [IMP] regulation of oskar mRNA translation [TAS] germ-line stem cell division [NAS] inter-male aggressive behavior [IMP] negative regulation of translation [IMP] mRNA polyadenylation [TAS]
Molecular Function:	nucleotide binding [IEA] protein binding [IPI][TAS] RNA binding [IDA] mRNA binding [ISS][NAS][TAS] mRNA 3'-UTR binding [IDA][TAS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFTSRASFLA NRRMIFDFSE KNNDIYLDAF GMSDKSSSAT NSLPNSPIHS NNNNPSLLNN  60
   61 NNNNSNGTSS NNSLNVGNNN SNPSLGGSNS NALVSVGSNG IMSAAGLVNN NNNPCSANRN 120
  121 VVAMVDDDAC FRLDTDATVT YGEKEPDPDN IKMFVGQVPK SMDESQLREM FEEYGAVHSI 180
  181 NVLRDKATGI SKGCCFVTFY TRHAALKAQD ALHNVKTLNG MYHPIQMKPA DSENRNERKL 240
  241 FVGMLNKKLN ENDVRKLFEV HGAIEECTVL RDQNGQSKGC AFVTFATKHA AISAIKVTLS 300
  301 QNKIMEGCTS PLVVKFADTQ KEKEQKKIQQ IQANLWNLAS NINIPLGQTA TSVTTPILPN 360
  361 PPQQPSPVLG ADAITPASIQ LLQQLQAVGL QHQLLQALTG LGAQQSSSAT DTSAVAAAGL 420
  421 LTPMTVQNLA AIAAMTQPSL SNAAAAAAAA TSPGSAQLTN TAALLWSDPN PMASAYMSTA 480
  481 AGLPQFGSAS ALSTSPLASV ALSAAAAAAA GKQIEGPEGC NLFIYHLPQE FTDTDLASTF 540
  541 LPFGNVISAK VFIDKQTSLS KCFGFVSFDN PDSAQVAIKA MNGFQVGTKR LKVQLKKPKD 600
  601 SKPY

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.69

Protein Overview: aret-PA, aret-PE

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: