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Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA. Any process that modulates the frequency, rate or extent of oskar mRNA translation. To ensure the localization of Oskar protein at the posterior pole of the oocyte, translation of oskar mRNA is repressed during its transport to the posterior pole and activated upon localization of the mRNA at the posterior cortex. Any process that stops, prevents or reduces the rate that oskar mRNAs are effectively translated into protein. Any process that decreases the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances, carried out by individual cells. The cellular metabolic process by which a protein is formed, using the sequence of a mature mRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA. Translation ends with the release of a polypeptide chain from the ribosome. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA. Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways involving a protein, occurring at the level of an individual cell.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: negative regulation of oskar mRNA translation
Acc: GO:0007319
Aspect: Biological Process
Desc: Any process that stops, prevents or reduces the rate that oskar mRNAs are effectively translated into protein.
Synonyms:
  • downregulation of oskar mRNA translation
  • inhibition of oskar mRNA translation
  • down-regulation of oskar mRNA translation
  • down regulation of oskar mRNA translation
Proteins in PDR annotated with:
   This term: 29 [Search]
   Term or descendants: 29 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0007319 - negative regulation of oskar mRNA translation (interactive image map)
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