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Protein Overview: FBpp0309202, piwi-PA

General Information:
Name(s) found: FBpp0309202 [FlyBase]
piwi-PA / FBpp0079755 [FlyBase]
Description(s) found:
Found 28 descriptions.
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  • type=protein; loc=2L:complement(10982658..10983540,10983666..10983776,10983896..10984087,10984141..10984341,10984946..10985100,10985167..10985487,10985544..10986128,10987249..10987332); ID=FBpp0309202; name=piwi-PB; parent=FBgn0004872,FBtr0340227; dbxref=FlyBase:FBpp0309202,FlyBase_Annotation_IDs:CG6122-PB; MD5=6c8cb1c1b601077b1eba3bfec87db137; length=843; release=r5.56; species=Dmel; [FlyBase]
  • The gene piwi is referred to in FlyBase by the symbol Dmel\piwi (CG6122, FBgn0004872). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:10982205..10987416. It has the cytological map location 32C1. There is experimental evidence that it has the molecular function</span>: protein binding; RNA binding. There is experimental evidence that it is involved in the biological process</span>: posttranscriptional gene silencing; male germ-line stem cell division; negative regulation of transposition, DNA-mediated; pole cell formation; stem cell division; female germ-line stem cell division; chromatin silencing. 21 alleles are reported. The phenotypes of these alleles are annotated with: ovariole; egg; ovary; male germline stem cell; spectrosome; testis; nurse cell spectrosome; female germline stem cell; egg chamber; germarium. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 843 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDA][TAS]
    polytene chromosome [IDA]
    euchromatin [IDA]
    telomeric heterochromatin [IDA]
    cytoplasm [NAS]
    chromocenter [IDA]
    nucleoplasm [NAS][TAS]
    Biological Process: male germ-line stem cell division [IMP]
    female germ-line stem cell division [IMP]
    germ-line stem cell maintenance [TAS]
    germ-line stem cell division [TAS]
    pole cell formation [IMP]
    stem cell division [IMP]
    posttranscriptional gene silencing [IMP]
    chromatin silencing [IMP]
    negative regulation of transposition, DNA-mediated [IMP]
    cell fate determination [TAS]
    RNA interference [TAS]
    Molecular Function: protein binding [IPI]
    RNA binding [IDA]
    mRNA binding [NAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MADDQGRGRR RPLNEDDSST SRGSGDGPRV KVFRGSSSGD PRADPRIEAS RERRALEEAP  60
   61 RREGGPTERK PWGDQYDYLN TRPAELVSKK GTDGVPVMLQ TNFFRLKTKP EWRIVHYHVE 120
  121 FEPSIENPRV RMGVLSNHAN LLGSGYLFDG LQLFTTRKFE QEITVLSGKS KLDIEYKISI 180
  181 KFVGFISCAE PRFLQVLNLI LRRSMKGLNL ELVGRNLFDP RAKIEIREFK MELWPGYETS 240
  241 IRQHEKDILL GTEITHKVMR TETIYDIMRR CSHNPARHQD EVRVNVLDLI VLTDYNNRTY 300
  301 RINDVDFGQT PKSTFSCKGR DISFVEYYLT KYNIRIRDHN QPLLISKNRD KALKTNASEL 360
  361 VVLIPELCRV TGLNAEMRSN FQLMRAMSSY TRMNPKQRTD RLRAFNHRLQ NTPESVKVLR 420
  421 DWNMELDKNV TEVQGRIIGQ QNIVFHNGKV PAGENADWQR HFRDQRMLTT PSDGLDRWAV 480
  481 IAPQRNSHEL RTLLDSLYRA ASGMGLRIRS PQEFIIYDDR TGTYVRAMDD CVRSDPKLIL 540
  541 CLVPNDNAER YSSIKKRGYV DRAVPTQVVT LKTTKNRSLM SIATKIAIQL NCKLGYTPWM 600
  601 IELPLSGLMT IGFDIAKSTR DRKRAYGALI ASMDLQQNST YFSTVTECSA FDVLANTLWP 660
  661 MIAKALRQYQ HEHRKLPSRI VFYRDGVSSG SLKQLFEFEV KDIIEKLKTE YARVQLSPPQ 720
  721 LAYIVVTRSM NTRFFLNGQN PPPGTIVDDV ITLPERYDFY LVSQQVRQGT VSPTSYNVLY 780
  781 SSMGLSPEKM QKLTYKMCHL YYNWSGTTRV PAVCQYAKKL ATLVGTNLHS IPQNALEKKF 840
  841 YYL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.95

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle