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Any process that modulates the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Some protein processing events may be included when they are required to form an active form of a product from an inactive precursor form. A posttranscriptional gene silencing process in which the silencing signal originates in a tissue separate from the tissue in which the silencing takes place. The posttranscriptional gene silencing of viral genes after viral infection. Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. The posttranscriptional gene silencing of host genes that are homologous to viral genes after viral infection. Any process that decreases the frequency, rate or extent of the inactivation of gene expression by a posttranscriptional mechanism. Any transcriptional or post-transcriptional process carried out at the cellular level that results in long-term gene inactivation. Any process that modulates the frequency, rate or extent of the inactivation of gene expression by a posttranscriptional mechanism. Any process that increases the frequency, rate or extent of the inactivation of gene expression by a posttranscriptional mechanism. The inactivation of gene expression by a posttranscriptional mechanism. Any process that modulates the frequency, rate or extent of gene expression after the production of an RNA transcript. Any process that decreases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Some protein processing events may be included when they are required to form an active form of a product from an inactive precursor form. Any process of posttranscriptional gene inactivation (silencing) mediated by small RNA molecules that may trigger mRNA degradation or negatively regulate translation. Any process that modulates the frequency, rate or extent of gene expression; the process is mitotically or meiotically heritable, or is stably self-propagated in the cytoplasm of a resting cell, and does not entail a change in DNA sequence.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: posttranscriptional gene silencing
Acc: GO:0016441
Aspect: Biological Process
Desc: The inactivation of gene expression by a posttranscriptional mechanism.
Synonyms:
  • PTGS
  • cosuppression
  • quelling
Proteins in PDR annotated with:
   This term: 11 [Search]
   Term or descendants: 213 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0016441 - posttranscriptional gene silencing (interactive image map)
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