Protein Overview: Traf4-PA

General Information:
Name(s) found:	Traf4-PA / FBpp0077119 [FlyBase]
Description(s) found: Found 25 descriptions. SHOW ALL	The gene TNF-receptor-associated factor 4 is referred to in FlyBase by the symbol Dmel\Traf4 (CG3048, FBgn0026319). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:4362549..4380725. It has the cytological map location 24E1-24E4. There is experimental evidence that it has the molecular function</span>: protein binding. There is experimental evidence that it is involved in the biological process</span>: instar larval development; eye development; asymmetric protein localization involved in cell fate determination; imaginal disc fusion, thorax closure; embryonic development; autophagic cell death; positive regulation of JNK cascade; positive regulation of apoptosis; salivary gland cell autophagic cell death; phagocytosis, engulfment. 11 alleles are reported. The phenotypes of these alleles are annotated with: eye disc; eye; eye photoreceptor cell; imaginal disc; ommatidium. It has 3 annotated transcripts and 3 annotated polypeptides. [FlyBase]
Organism:	Drosophila melanogaster
Length:	486 amino acids
Gene Ontology:
Cellular Component:	cytoplasm [IDA] apical cortex [IDA]
Biological Process:	dorsal closure [TAS] Toll signaling pathway [NAS] embryonic development [IEP] imaginal disc fusion, thorax closure [IGI] signal transduction [NAS] salivary gland cell autophagic cell death [IEP] defense response [NAS] instar larval development [IEP] eye development [IMP] phagocytosis, engulfment [IMP] asymmetric protein localization involved in cell fate determination [IMP] autophagic cell death [IEP] positive regulation of JNK cascade [IGI] positive regulation of apoptosis [IMP]
Molecular Function:	zinc ion binding [IEA] protein binding [IPI]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVRSLAQWTK TLSFPSRLSP NRNSKDCSTL ASPVPPPTPP RNKTTSGSGN CATSRSSSST  60
   61 VSSSHSSSHS SPTPGNNNNN MPITELEQII YPGPDPKHIM GSLVFCIHHK QGCKWSDELR 120
  121 KLKGHLNACK HDATQCPNKC GAQIPRIMMT DHLQYTCTMR RTRCEFCQSE FSGAGLEEHN 180
  181 GSCGQEPVYC EAKCGQRILR GRMTLHKSKD CAKRLRRCAH CQREFSADTL PLHAAQCPRA 240
  241 PLACPQRCDA GPIPRGELEA HLRDECQSLA VSCSFKEAGC RFKGPRQMLE AHLESNAAAH 300
  301 LSLMVALSSR QGQQIQMLKS AVSKLSINYT GTLLWKITDW SAKMAEARGK DGLELVSPPF 360
  361 YTSQYGYKLQ ASMFLNGNGP GENTHVSVYI KVLPGEYDAL LKWPFSHSIT FTLFEQGAQS 420
  421 GQGGVAESFV PDPTWENFQR PSNEPDQLGF GFPRFISHEL LHSRPFIKGD TVFLRVKVDP 480
  481 SKIVAV

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.97

Protein Overview: Traf4-PA

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: