Protein Overview: GBRL2_RAT

General Information:
Name(s) found:	GBRL2_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|56789882\|gb\|AAH88139.1\| GABA(A) receptor-associated protein like 2 [Rattus norvegicus] [NCBI NR] gi\|44920666\|sp\|P60522.1\|GBRL2_RAT RecName: Full=Gamma-aminobutyric acid receptor-associated protein-like 2; AltName: Full=GABA(A) receptor-associated protein-like 2; AltName: Full=Golgi-associated ATPase enhancer of 16 kDa; Short=GATE-16; AltName: Full=Ga [NCBI NR] gi\|34786053\|gb\|AAH58145.1\| GABA(A) receptor-associated protein like 2 [Rattus norvegicus] [NCBI NR] gi\|2104570\|dbj\|BAA19975.1\| GEF-2 [Rattus norvegicus] [NCBI NR] gi\|149038235\|gb\|EDL92595.1\| rCG51056, isoform CRA_a [Rattus norvegicus] [NCBI NR] gi\|12083673\|ref\|NP_073197.1\| GABA(A) receptor-associated protein like 2 [Rattus norvegicus] [NCBI NR] (P60522) Gamma-aminobutyric acid receptor-associated protein-like 2 (GABA(A) receptor-associated protein-like 2) (Ganglioside expression factor 2) (GEF-2) [Swiss-Prot] Gamma-aminobutyric acid receptor-associated protein-like 2 OS=Rattus norvegicus GN=Gabarapl2 PE=3 SV=1 [Swiss-Prot] Ensembl_locations(Chr-bp):8-91809380 Ganglioside expression factor 2 [hmr_yeast5_DM3-1_pombe.fasta] GABA(A) receptor-associated protein like 2; ganglioside expression factor 2 [HMR_022704-rand.fasta] gamma-aminobutyric acid (GABA-A) receptor-associated protein-like 2 [Mus musculus]gi\|27807219\|ref\|NP_777100.1\| GABA(A) receptor-associated protein-like 2 [Bos taurus]gi\|6005768\|ref\|NP_009216.1\| GABA(A) receptor-associated protein-like 2 [Homo sapiens]g [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Gamma-aminobutyric acid receptor-associated protein-like 2 [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] (NM_022706) GABA(A) receptor-associated protein like 2; ganglioside expression factor 2 [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] Gamma-aminobutyric acid receptor-associated protein-like 2 (GABA(A) receptor-associated protein-like 2) (Ganglioside expression factor 2) (GEF-2) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] GABA(A) receptor-associated protein like 2 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] rCG51056, isoform CRA_a [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] GEF-2 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 GAMMA-AMINOBUTYRIC ACID RECEPTOR-ASSOCIATED PROTEIN-LIKE 2 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=10116 Gene_Symbol=Gabarapl2 Gamma-aminobutyric acid receptor-associated protein-like 2 [rat-ipi-250309-contam.fasta] gamma-aminobutyric acid receptor-associated protein-like 2 [Rattus norvegicus] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta] Gamma-aminobutyric acid receptor-associated protein-like 2 OS=Rattus norvegicus GN=Gabarapl2 [011711_HMR.fasta] Gamma-aminobutyric acid receptor-associated protein-like 2 OS=Rattus norvegicus GN=Gabarapl2 PE=2 SV=1 [UNIPROT_RAT_07-21-2011_reversed.fasta]
Organism:	Rattus norvegicus
Length:	117 amino acids
Gene Ontology:
Cellular Component:	membrane fraction [UNKNOWN] Golgi membrane [UNKNOWN] Golgi apparatus [UNKNOWN][IEA] cellular_component [ND] autophagic vacuole membrane [UNKNOWN] intracellular [UNKNOWN]
Biological Process:	biological_process [ND] protein transport [IEA]
Molecular Function:	protein binding [UNKNOWN] molecular_function [ND]

Sequence:
Sequence: [PDR BLAST] [ProtParam]	1 11 21 31 41 51 \| \| \| \| \| \| 1 MKWMFKEDHS LEHRCVESAK IRAKYPDRVP VIVEKVSGSQ IVDIDKRKYL VPSDITVAQF 60 61 MWIIRKRIQL PSEKAIFLFV DKTVPQSSLT MGQLYEKEKD EDGFLYVAYS GENTFGF

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Microscopy / Localization Data

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No microscopy data found in the PDR for this protein.

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..117]	PSI-BLAST	60.522879	Golgi-associated ATPase enhancer of 16 kD, Gate-16

Functions predicted (by domain):

#

Gene Ontology predictions

1

Term	Confidence	Notes
tubulin binding	3.8719684227967	bayes_pls_golite062009
small conjugating protein ligase activity	3.71144418714309	bayes_pls_golite062009
microtubule binding	3.61517229466799	bayes_pls_golite062009
ubiquitin-protein ligase activity	3.30801071565148	bayes_pls_golite062009
cytoskeletal protein binding	3.11253399564789	bayes_pls_golite062009
beta-tubulin binding	2.878827078106	bayes_pls_golite062009
binding	2.786655943372	bayes_pls_golite062009
acid-amino acid ligase activity	2.72499875710239	bayes_pls_golite062009
GABA receptor binding	2.41579236188889	bayes_pls_golite062009
protein tag	2.15059229834935	bayes_pls_golite062009
protein binding	1.86841453215444	bayes_pls_golite062009
transcription regulator activity	1.42747465816672	bayes_pls_golite062009
nucleic acid binding	1.32707653701567	bayes_pls_golite062009
DNA binding	1.22622447288034	bayes_pls_golite062009
molecular transducer activity	0.87452559909702	bayes_pls_golite062009
signal transducer activity	0.87452559909702	bayes_pls_golite062009
SUMO ligase activity	0.80391127659342	bayes_pls_golite062009
hydrolase activity	0.79940718386175	bayes_pls_golite062009
ligase activity, forming carbon-nitrogen bonds	0.753885975469065	bayes_pls_golite062009
structural constituent of ribosome	0.599634454232833	bayes_pls_golite062009
structural molecule activity	0.576819726104993	bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor	0.536856055841234	bayes_pls_golite062009
kinase activity	0.506057697290914	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	0.410719674374641	bayes_pls_golite062009
protein kinase activity	0.325253662829604	bayes_pls_golite062009
enzyme binding	0.240262781026149	bayes_pls_golite062009
transferase activity	0.236208643697075	bayes_pls_golite062009

Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

Philius Transmembrane Prediction:

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Source: Reynolds et al. (2008)

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle