Protein Overview: XPO1_RAT

General Information:
Name(s) found:	XPO1_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|68052857\|sp\|Q80U96.1\|XPO1_RAT RecName: Full=Exportin-1; Short=Exp1; AltName: Full=Chromosome region maintenance 1 protein homolog [NCBI NR] gi\|29789299\|ref\|NP_445942.1\| exportin 1, CRM1 homolog [Rattus norvegicus] [NCBI NR] gi\|28971720\|dbj\|BAC65240.1\| nuclear export factor CRM1 [Rattus norvegicus] [NCBI NR] gi\|149044799\|gb\|EDL97985.1\| exportin 1, CRM1 homolog (yeast), isoform CRA_a [Rattus norvegicus] [NCBI NR] gi\|149044798\|gb\|EDL97984.1\| exportin 1, CRM1 homolog (yeast), isoform CRA_a [Rattus norvegicus] [NCBI NR] Exportin-1 OS=Rattus norvegicus GN=Xpo1 PE=1 SV=1 [Swiss-Prot] Ensembl_locations(Chr-bp):14-94967422 Nuclear export factor CRM1 [hmr_yeast5_DM3-1_pombe.fasta] exportin 1 (CRM1, yeast, homolog) [HMR_022704-rand.fasta] exportin 1 (CRM1, yeast, homolog) [Rattus norvegicus]gi\|28971720\|dbj\|BAC65240.1\| nuclear export factor CRM1 [Rattus norvegicus] [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Ensembl_locations(Chr-bp):14-94967422 Nuclear export factor CRM1 [EBI-IPI_Drosophila_na_12-13-2007_con_reversed.fasta] Exportin-1 (Exp1) (Chromosome region maintenance 1 protein homolog) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] exportin 1, CRM1 homolog [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] exportin 1, CRM1 homolog (yeast), isoform CRA_a [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] nuclear export factor CRM1 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] exportin-1 [Rattus norvegicus] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta] Exportin-1 OS=Rattus norvegicus GN=Xpo1 [011711_HMR.fasta] Exportin-1 OS=Rattus norvegicus GN=Xpo1 PE=2 SV=1 [UNIPROT_RAT_07-21-2011_reversed.fasta]
Organism:	Rattus norvegicus
Length:	1071 amino acids
Gene Ontology:
Cellular Component:	nucleus [UNKNOWN][IEA] ribonucleoprotein complex [UNKNOWN][IEA] cytoplasm [IEA] Cajal body [IEA] cytosol [UNKNOWN] kinetochore [UNKNOWN][ISS] annulate lamellae [UNKNOWN][IEA] nucleolus [IEA] nucleoplasm [UNKNOWN][IEA]
Biological Process:	regulation of centrosome duplication [UNKNOWN][IEA] regulation of protein catabolic process [UNKNOWN][IEA] protein export from nucleus [UNKNOWN][IDA] intracellular protein transport [IEA] response to virus [IDA] protein localization in nucleus [UNKNOWN][IEA] mRNA transport [IEA]
Molecular Function:	RNA binding [IEA] protein binding [UNKNOWN][IDA] protein transporter activity [UNKNOWN][IEA] binding [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPAIMTMLAD HAARQLLDFS QKLDINLLDN VVNCLYHGEG AQQRMAQEVL THLKEHPDAW  60
   61 TRVDTILEFS QNMNTKYYGL QILENVIKTR WKILPRNQCE GIKKYVVGLI IKTSSDPTCV 120
  121 EKEKVYIGKL NMILVQILKQ EWPKHWPTFI SDIVGASRTS ESLCQNNMVI LKLLSEEVFD 180
  181 FSSGQITQVK AKHLKDSMCN EFSQIFQLCQ FVMENSQNAP LVHATLETLL RFLNWIPLGY 240
  241 IFETKLISTL IYKFLNVPMF RNVSLKCLTE IAGVSVSQYE EQFETLFTLT MMQLKQMLPL 300
  301 NTNIRLAYSN GKDDEQNFIQ NLSLFLCTFL KEHGQLLEKR LNLREALMEA LHYMLLVSEV 360
  361 EETEIFKICL EYWNHLAAEL YRESPFSTSA SPLLSGSQHF DIPPRRQLYL TVLSKVRLLM 420
  421 VSRMAKPEEV LVVENDQGEV VREFMKDTDS INLYKNMRET LVYLTHLDYV DTEIIMTKKL 480
  481 QNQVNGTEWS WKNLNTLCWA IGSISGAMHE EDEKRFLVTV IKDLLGLCEQ KRGKDNKAII 540
  541 ASNIMYIVGQ YPRFLRAHWK FLKTVVNKLF EFMHETHDGV QDMACDTFIK IAQKCRRHFV 600
  601 QVQVGEVMPF IDEILNNINT IICDLQPQQV HTFYEAVGYM IGAQTDQTVQ EHLIEKYMLL 660
  661 PNQVWDSIIQ QATKNVDILK DPETVKQLGS ILKTNVRACK AVGHPFVIQL GRIYLDMLNV 720
  721 YKCLSENISA AIQANGEMVT KQPLIRSMRT VKRETLKLIS GWVSRSNDPQ MVAENFVPPL 780
  781 LDAVLIDYQR NVPAAREPEV LSTMAIIVNK LGGHITAEIP QIFDAVFECT LNMINKDFEE 840
  841 YPEHRTNFFL LLQAVNSHCF PAFLAIPPAQ FKLVLDSIIW AFKHTMRNVA DTGLQILFTL 900
  901 LQNVAQEEAA AQSFYQTYFC DILQHIFSVV TDTSHTAGLT MHASILAYMF NLVEEGKIST 960
  961 PLNPGSPVSN QMFIQDYVAN LLKSAFPHLQ DAQVKLFVTG LFSLNQDIPA FKEHLRDFLV1020
 1021 QIKEFAGEDT SDLFLEERET ALRQAQEEKH KLQMSVPGIL NPHEIPEEMC D

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.95

Protein Overview: XPO1_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: