Protein Overview: TIMP3_RAT

General Information:
Name(s) found:	TIMP3_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|971206\|gb\|AAA75002.1\| tissue inhibitor of metalloproteinase 3 [NCBI NR] ref\|NP_037018.1\| tissue inhibitor of metalloproteinase 3 (Sorsby fundus dystrophy, pseudoinflammatory) [Rattus norvegicus] [NCBI NR] pir\|\|JC4630 metalloproteinase tissue inhibitor 3 precursor - rat [NCBI NR] gi\|1351251\|sp\|P48032.1\|TIMP3_RAT RecName: Full=Metalloproteinase inhibitor 3; AltName: Full=Tissue inhibitor of metalloproteinases 3; Short=TIMP-3; Flags: Precursor [NCBI NR] Metalloproteinase inhibitor 3 OS=Rattus norvegicus GN=Timp3 PE=2 SV=1 [Swiss-Prot] (P48032) Metalloproteinase inhibitor 3 precursor (TIMP-3) (Tissue inhibitor of metalloproteinases-3) [Swiss-Prot] Ensembl_locations(Chr-bp):7-10733776;7-10733776;7-10733776 Metalloproteinase inhibitor 3 precursor [hmr_yeast5_DM3-1_pombe.fasta] tissue inhibitor of metalloproteinase 3 [HMR_022704-rand.fasta] tissue inhibitor of metalloproteinase 3 (Sorsby fundus dystrophy, pseudoinflammatory) [Rattus norvegicus]gi\|1351251\|sp\|P48032\|TIM3_RAT Metalloproteinase inhibitor 3 precursor (TIMP-3) (Tissue inhibitor of metalloproteinases-3)gi\|2118419\|pir\|\|JC4630 meta [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Metalloproteinase inhibitor 3 precursor [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] (NM_012886) tissue inhibitor of metalloproteinase 3 [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] Metalloproteinase inhibitor 3 precursor (Tissue inhibitor of metalloproteinases 3) (TIMP-3) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 METALLOPROTEINASE INHIBITOR 3 PRECURSOR [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Metalloproteinase inhibitor 3 precursor (TIMP-3) (Tissue inhibitor of metalloproteinases 3) [nr-271106-contam.fasta] Tax_Id=10116 Gene_Symbol=Timp3 Metalloproteinase inhibitor 3 [rat-ipi-250309-contam.fasta] Metalloproteinase inhibitor 3 OS=Rattus norvegicus GN=Timp3 [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	211 amino acids
Gene Ontology:
Cellular Component:	basement membrane [UNKNOWN][IEA] cytoplasm [IDA] extracellular region [IEA] cellular_component [ND]
Biological Process:	response to organic substance [IEP] response to estrogen stimulus [IEP] response to amino acid stimulus [IEP] negative regulation of proteolysis [IMP] response to organic cyclic substance [IEP] aging [IEP] response to hormone stimulus [IEP] tissue regeneration [IEP] response to mechanical stimulus [IEP] central nervous system development [IEP] induction of apoptosis [TAS] negative regulation of membrane protein ectodomain proteolysis [UNKNOWN][IEA] response to folic acid [IEP]
Molecular Function:	protein binding [UNKNOWN][IEA] enzyme inhibitor activity [IEA] metal ion binding [IEA] metalloendopeptidase inhibitor activity [TAS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTPWLGLVVL LSCWSLGHWG TEACTCSPSH PQDAFCNSDI VIRAKVVGKK LVKEGPFGTL  60
   61 VYTIKQMKMY RGFSKMPHVQ YIHTEASESL CGLKLEVNKY QYLLTGRVYE GKMYTGLCNF 120
  121 VERWDHLTLS QRKGLNYRYH LGCNCKIKSC YYLPCFVTSK KECLWTDMLS NFGYPGYQSK 180
  181 HYACIRQKGG YCSWYRGWAP PDKSISNATD P

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: TIMP3_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: