Protein Overview: DRD5_RAT

General Information:
Name(s) found:	DRD5_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|6978781\|ref\|NP_036900.1\| dopamine receptor D5 [Rattus norvegicus] [NCBI NR] gi\|203896\|gb\|AAA41072.1\| dopamine D1B receptor [NCBI NR] gi\|118251\|sp\|P25115.1\|DRD5_RAT RecName: Full=D(1B) dopamine receptor; AltName: Full=D(5) dopamine receptor [NCBI NR] pir\|\|A41271 dopamine receptor D5 - rat [NCBI NR] D(1B) dopamine receptor OS=Rattus norvegicus GN=Drd5 PE=2 SV=1 [Swiss-Prot] (P25115) D(1B) dopamine receptor (D(5) dopamine receptor) [Swiss-Prot] Ensembl_locations(Chr-bp):14-68841600 D [hmr_yeast5_DM3-1_pombe.fasta] dopamine receptor 5; Dopamine receptor D5 [HMR_022704-rand.fasta] dopamine receptor 5 [Rattus norvegicus]gi\|111597\|pir\|\|A41271 dopamine receptor D5 - ratgi\|203896\|gb\|AAA41072.1\| dopamine D1B receptorgi\|118251\|sp\|P25115\|DBDR_RAT D(1B) dopamine receptor (D(5) dopamine receptor) [nrdb_11152004_Chlamydomonas] Tax_Id=10116 D(1B) dopamine receptor [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] (NM_012768) dopamine receptor D5 [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] Tax_Id=10116 D [EBI-IPI_rat_3.05_04-04-2005_origrev.fasta] D(1B) dopamine receptor (D(5) dopamine receptor) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] dopamine receptor D5 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] dopamine D1B receptor [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] dopamine receptor 5 [Rattus norvegicus] [nr-271106-contam.fasta] Tax_Id=10116 Gene_Symbol=Drd5 D(1B) dopamine receptor [rat-ipi-250309-contam.fasta] D(1B) dopamine receptor OS=Rattus norvegicus GN=Drd5 [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	475 amino acids
Gene Ontology:
Cellular Component:	brush border membrane [UNKNOWN][IDA] integral to membrane [IEA] plasma membrane [UNKNOWN][IEA]
Biological Process:	activation of adenylate cyclase activity by dopamine receptor signaling pathway [UNKNOWN][IMP] regulation of female receptivity [UNKNOWN][IEA] dopamine receptor signaling pathway [IDA][IMP] visual learning [IMP] positive regulation of adenylate cyclase activity [UNKNOWN] associative learning [UNKNOWN][IEA] negative regulation of protein kinase activity [IMP] regulation of systemic arterial blood pressure by vasopressin [UNKNOWN][IEA] wound healing [UNKNOWN][IEA] synaptic transmission, dopaminergic [IMP] sensitization [UNKNOWN][IEA] regulation of long-term neuronal synaptic plasticity [IMP] long term synaptic depression [UNKNOWN][IEA] transmission of nerve impulse [UNKNOWN][IEA] signal transduction [IEA] positive regulation of cAMP biosynthetic process [IMP] response to cocaine [UNKNOWN][IEA] negative regulation of blood pressure [UNKNOWN][IEA] activation of adenylate cyclase activity by G-protein signaling pathway [UNKNOWN][IDA] norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure [UNKNOWN][IEA] mating behavior [UNKNOWN][IEA] oxygen and reactive oxygen species metabolic process [UNKNOWN][IEA] response to amphetamine [UNKNOWN][IEA] negative regulation of NAD(P)H oxidase activity [UNKNOWN][IEA] negative regulation of cell migration [IMP]
Molecular Function:	G-protein coupled receptor activity [IEA] dopamine receptor activity [UNKNOWN][IDA] dopamine receptor activity, coupled via Gs [UNKNOWN] dopamine D5 receptor activity [UNKNOWN][IMP] drug binding [IDA] G-protein alpha-subunit binding [IPI] dopamine binding [UNKNOWN] receptor activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLPPGRNRTA QPARLGLQRQ LAQVDAPAGS ATPLGPAQVV TAGLLTLLIV WTLLGNVLVC  60
   61 AAIVRSRHLR AKMTNIFIVS LAVSDLFVAL LVMPWKAVAE VAGYWPFGTF CDIWVAFDIM 120
  121 CSTASILNLC IISVDRYWAI SRPFRYERKM TQRVALVMVG LAWTLSILIS FIPVQLNWHR 180
  181 DKAGSQGQEG LLSNGTPWEE GWELEGRTEN CDSSLNRTYA ISSSLISFYI PVAIMIVTYT 240
  241 RIYRIAQVQI RRISSLERAA EHAQSCRSRG AYEPDPSLRA SIKKETKVFK TLSMIMGVFV 300
  301 CCWLPFFILN CMVPFCSSGD AEGPKTGFPC VSETTFDIFV WFGWANSSLN PIIYAFNADF 360
  361 RKVFAQLLGC SHFCFRTPVQ TVNISNELIS YNQDTVFHKE IATAYVHMIP NAVSSGDREV 420
  421 GEEEEEGPFD HMSQISPTTP DGDLAAESVW ELDCEEEVSL GKISPLTPNC FDKTA

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: DRD5_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: