Protein Overview: ACHA_RAT

General Information:
Name(s) found:	ACHA_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|398832\|emb\|CAA52826.1\| acetylcholine receptor alpha-subunit [Rattus norvegicus] [NCBI NR] gi\|149022258\|gb\|EDL79152.1\| cholinergic receptor, nicotinic, alpha polypeptide 1 (muscle), isoform CRA_b [Rattus norvegicus] [NCBI NR] gi\|13324700\|ref\|NP_077811.1\| cholinergic receptor, nicotinic, alpha polypeptide 1 [Rattus norvegicus] [NCBI NR] gi\|113075\|sp\|P25108.1\|ACHA_RAT RecName: Full=Acetylcholine receptor subunit alpha; Flags: Precursor [NCBI NR] pir\|\|S13872 nicotinic acetylcholine receptor alpha chain precursor - rat [NCBI NR] Acetylcholine receptor subunit alpha OS=Rattus norvegicus GN=Chrna1 PE=2 SV=1 [Swiss-Prot] Ensembl_locations(Chr-bp):3-164326830 Acetylcholine receptor protein, alpha chain precursor [hmr_yeast5_DM3-1_pombe.fasta] cholinergic receptor, nicotinic, alpha polypeptide 1; cholinergic receptor, nicotinic, alpha polypeptide 1 (muscle); cholinergic receptor nicotinic alpha polypeptide 1 (muscle) [HMR_022704-rand.fasta] cholinergic receptor, nicotinic, alpha polypeptide 1 [Rattus norvegicus]gi\|398832\|emb\|CAA52826.1\| acetylcholine receptor alpha-subunit [Rattus norvegicus]gi\|113075\|sp\|P25108\|ACHA_RAT Acetylcholine receptor protein, alpha chain precursorgi\|112054\|pir\|\|S [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Acetylcholine receptor protein, alpha subunit precursor [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] (NM_024485) cholinergic receptor, nicotinic, alpha polypeptide 1; cholinergic receptor, nicotinic, alpha polypeptide 1 (muscle) [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] Tax_Id=10116 Acetylcholine receptor protein, alpha chain precursor [EBI-IPI_rat_3.05_04-04-2005_origrev.fasta] Acetylcholine receptor subunit alpha precursor [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] cholinergic receptor, nicotinic, alpha polypeptide 1 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] cholinergic receptor, nicotinic, alpha polypeptide 1 (muscle), isoform CRA_b [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] acetylcholine receptor alpha-subunit [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 ACETYLCHOLINE RECEPTOR PROTEIN, ALPHA CHAIN PRECURSOR [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Acetylcholine receptor protein subunit alpha precursor [nr-271106-contam.fasta] Tax_Id=10116 Gene_Symbol=Chrna1 Acetylcholine receptor subunit alpha [rat-ipi-250309-contam.fasta] Acetylcholine receptor subunit alpha OS=Rattus norvegicus GN=Chrna1 [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	457 amino acids
Gene Ontology:
Cellular Component:	postsynaptic membrane [IEA] integral to membrane [IEA] cell junction [IEA] neuromuscular junction [UNKNOWN][IEA] nicotinic acetylcholine-gated receptor-channel complex [UNKNOWN][TAS] plasma membrane [UNKNOWN][IEA] cell surface [UNKNOWN][IEA]
Biological Process:	neuromuscular junction development [UNKNOWN][IEA] ion transport [IEA] muscle cell homeostasis [UNKNOWN][IEA] musculoskeletal movement [UNKNOWN] neuron homeostasis [UNKNOWN][IEA] regulation of membrane potential [UNKNOWN][IEA] skeletal muscle contraction [UNKNOWN][IEA] neuromuscular synaptic transmission [UNKNOWN][IEA] skeletal muscle tissue growth [UNKNOWN][IEA] neuromuscular process [UNKNOWN][IEA] regulation of action potential in neuron [UNKNOWN][IEA]
Molecular Function:	ion channel activity [IEA] nicotinic acetylcholine-activated cation-selective channel activity [UNKNOWN][IDA] acetylcholine receptor activity [IEA] extracellular ligand-gated ion channel activity [IEA] acetylcholine binding [UNKNOWN] receptor activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MELTAVLLLL GLCSAGTVLG SEHETRLVAK LFKDYSSVVR PVGDHREIVQ VTVGLQLIQL  60
   61 INVDEVNQIV TTNVRLKQQW VDYNLKWNPD DYGGVKKIHI PSEKIWRPDV VLYNNADGDF 120
  121 AIVKFTKVLL DYTGHITWTP PAIFKSYCEI IVTHFPFDEQ NCSMKLGTWT YDGSVVAINP 180
  181 ESDQPDLSNF MESGEWVIKE ARGWKHWVFY SCCPNTPYLD ITYHFVMQRL PLYFIVNVII 240
  241 PCLLFSFLTS LVFYLPTDSG EKMTLSISVL LSLTVFLLVI VELIPSTSSA VPLIGKYMLF 300
  301 TMVFVIASII ITVIVINTHH RSPSTHIMPE WVRKVFIDTI PNIMFFSTMK RPSRDKQEKR 360
  361 IFTEDIDISD ISGKPGPPPM GFHSPLIKHP EVKSAIEGVK YIAETMKSDQ ESNNASEEWK 420
  421 YVAMVMDHIL LGVFMLVCLI GTLAVFAGRL IELHQQG

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: ACHA_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: