Protein Overview: IL1RA_RAT

General Information:
Name(s) found:	IL1RA_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|204929\|gb\|AAA41434.1\| interleukin 1 receptor antagonist [NCBI NR] gi\|149039442\|gb\|EDL93662.1\| interleukin 1 receptor antagonist, isoform CRA_a [Rattus norvegicus] [NCBI NR] gi\|124315\|sp\|P25086.1\|IL1RA_RAT RecName: Full=Interleukin-1 receptor antagonist protein; Short=IL-1ra; Short=IL-1RN; Short=IRAP; AltName: Full=IL1 inhibitor; Flags: Precursor [NCBI NR] gi\|11559964\|ref\|NP_071530.1\| interleukin 1 receptor antagonist [Rattus norvegicus] [NCBI NR] pir\|\|C40956 interleukin-1 receptor antagonist precursor - rat [NCBI NR] (P25086) Interleukin-1 receptor antagonist protein precursor (IL-1ra) (IRAP) (IL1 inhibitor) (IL-1RN) [Swiss-Prot] Interleukin-1 receptor antagonist protein OS=Rattus norvegicus GN=Il1rn PE=2 SV=1 [Swiss-Prot] Ensembl_locations(Chr-bp):3-2492734 Interleukin-1 receptor antagonist protein precursor [hmr_yeast5_DM3-1_pombe.fasta] interleukin 1 receptor antagonist gene; Interleukin 1 receptor antagonist [HMR_022704-rand.fasta] interleukin 1 receptor antagonist gene [Rattus norvegicus]gi\|124315\|sp\|P25086\|IL1X_RAT Interleukin-1 receptor antagonist protein precursor (IL-1ra) (IRAP) (IL1 inhibitor) (IL-1RN)gi\|111881\|pir\|\|C40956 interleukin-1 receptor antagonist precursor - ratgi [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Interleukin-1 receptor antagonist protein precursor [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] (NM_022194) interleukin 1 receptor antagonist gene [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] Interleukin-1 receptor antagonist protein precursor (IL-1ra) (IL-1RN) (IRAP) (IL1 inhibitor) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] interleukin 1 receptor antagonist [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] interleukin 1 receptor antagonist, isoform CRA_a [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] interleukin 1 receptor antagonist [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 INTERLEUKIN-1 RECEPTOR ANTAGONIST PROTEIN PRECURSOR [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Interleukin-1 receptor antagonist protein precursor (IL-1ra) (IRAP) (IL1 inhibitor) (IL-1RN) [nr-271106-contam.fasta] Tax_Id=10116 Gene_Symbol=Il1rn Interleukin-1 receptor antagonist protein [rat-ipi-250309-contam.fasta] Interleukin-1 receptor antagonist protein OS=Rattus norvegicus GN=Il1rn [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	178 amino acids
Gene Ontology:
Cellular Component:	extracellular space [UNKNOWN][IDA][IEA] cytoplasm [UNKNOWN] vesicle [UNKNOWN][IEA] extracellular region [UNKNOWN][IEA]
Biological Process:	positive regulation of JUN kinase activity [IMP] insulin secretion [UNKNOWN][IEA] female pregnancy [IEP] negative regulation of glutamate secretion [IMP] response to organic cyclic substance [IEP] fever [IMP] memory [IMP] inflammatory response [UNKNOWN] negative regulation of signal transduction [TAS] chronic inflammatory response to antigenic stimulus [IEP] response to drug [IEP] negative regulation of apoptosis [IMP] lipid metabolic process [UNKNOWN][IEA] response to glucocorticoid stimulus [UNKNOWN] response to lipopolysaccharide [IEP] response to organic nitrogen [IEP]
Molecular Function:	protein binding [UNKNOWN] interleukin-1, Type I receptor binding [TAS] interleukin-1 receptor antagonist activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEICRGPYSH LISLLLILLF RSESAGHPAG KRPCKMQAFR IWDTNQKTFY LRNNQLIAGY  60
   61 LQGPNTKLEE KIDMVPIDFR NVFLGIHGGK LCLSCVKSGD DTKLQLEEVN ITDLNKNKEE 120
  121 DKRFTFIRSE TGPTTSFESL ACPGWFLCTT LEADHPVSLT NTPKEPCTVT KFYFQEDQ

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: IL1RA_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: