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Interacts with the fibroblast growth factor receptor to reduce the action of another ligand, the agonist. Blocks the binding of interleukin-1 to interleukin-1 Type I receptors. Interacting selectively and non-covalently with one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function. Interacting selectively and non-covalently with the fibroblast growth factor receptor (FGFR). Blocks the binding of interleukin-1 to interleukin-1 Type II receptors. Blocks the binding of interleukin-1 to the interleukin-1 receptor complex. Interacts with receptors to reduce the action of another ligand, the agonist. Interacting selectively with a cytokine receptor.

View Gene Ontology (GO) Term

GO TERM SUMMARY

Name: interleukin-1 receptor antagonist activity
Acc: GO:0005152
Aspect: Molecular Function
Desc: Blocks the binding of interleukin-1 to the interleukin-1 receptor complex.
Synonyms:
  • IL-1ra
Proteins in PDR annotated with:
   This term: 9 [Search]
   Term or descendants: 9 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0005152 - interleukin-1 receptor antagonist activity (interactive image map)

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle