Protein Overview: HFE_RAT

General Information:
Name(s) found:	HFE_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|47477797\|gb\|AAH70942.1\| Hemochromatosis [Rattus norvegicus] [NCBI NR] gi\|3219801\|sp\|O35799.1\|HFE_RAT RecName: Full=Hereditary hemochromatosis protein homolog; AltName: Full=RT1-CAFE; Flags: Precursor [NCBI NR] gi\|25742831\|ref\|NP_445753.1\| hemochromatosis [Rattus norvegicus] [NCBI NR] gi\|2398787\|emb\|CAA04799.1\| hereditary haemochromatosis-like protein [Rattus norvegicus] [NCBI NR] gi\|149031605\|gb\|EDL86572.1\| hemochromatosis, isoform CRA_d [Rattus norvegicus] [NCBI NR] Hereditary hemochromatosis protein homolog OS=Rattus norvegicus GN=Hfe PE=2 SV=1 [Swiss-Prot] Ensembl_locations(Chr-bp):17-50660016 Hereditary hemochromatosis protein homolog precursor [hmr_yeast5_DM3-1_pombe.fasta] hemochromatosis [HMR_022704-rand.fasta] hemochromatosis [Rattus norvegicus]gi\|47477797\|gb\|AAH70942.1\| Hemochromatosis [Rattus norvegicus]gi\|2398787\|emb\|CAA04799.1\| hereditary haemochromatosis-like protein [Rattus norvegicus]gi\|3219801\|sp\|O35799\|HFE_RAT Hereditary hemochromatosis protein homo [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Hereditary hemochromatosis protein homolog precursor [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] Hereditary hemochromatosis protein homolog precursor (RT1-CAFE) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] hemochromatosis [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] hemochromatosis, isoform CRA_d [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Hemochromatosis [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] hereditary haemochromatosis-like protein [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 HEREDITARY HEMOCHROMATOSIS PROTEIN HOMOLOG PRECURSOR [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=10116 Gene_Symbol=Hfe Hereditary hemochromatosis protein homolog [rat-ipi-250309-contam.fasta] hemochromatosis isoform 1 precursor [Rattus norvegicus] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta] Hereditary hemochromatosis protein homolog OS=Rattus norvegicus GN=Hfe [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	360 amino acids
Gene Ontology:
Cellular Component:	[NOT]microvillus membrane [IDA] early endosome [UNKNOWN][IEA] perinuclear region of cytoplasm [UNKNOWN][IEA] apical part of cell [UNKNOWN][IDA] basal part of cell [UNKNOWN][IEA] membrane [IEA] integral to membrane [IEA] cytoplasmic vesicle [UNKNOWN][IEA] recycling endosome [UNKNOWN][IEA] MHC class I protein complex [IEA]
Biological Process:	cellular iron ion homeostasis [TAS] iron ion homeostasis [UNKNOWN] immune response [IEA] multicellular organismal iron ion homeostasis [UNKNOWN][IEA] female pregnancy [IEP] antigen processing and presentation [IEA] cellular response to iron ion starvation [IEP] antigen processing and presentation of peptide antigen via MHC class I [IEA] hormone biosynthetic process [UNKNOWN][IEA]
Molecular Function:	protein binding [UNKNOWN][IEA] molecular_function [ND]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDRSAGLPVR LLLLLLLLLL WSVAPQALRP GSHSLRYLFM GASKPDLGLP FFEALGYVDD  60
   61 QLFVSYNHES RRAEPRAPWI LGQTSSQLWL QLSQSLKGWD YMFIVDFWTI MGNYNHSKVT 120
  121 KLRVVPESHI LQVILGCEVH EDNSTSGFWK YGYDGQDHLE FCPKTLNWSA AEPRAWATKM 180
  181 EWEEHRIRAR QSRDYLQRDC PQQLKQVLEL QRGVLGQQVP TLVKVTRHWA STGTSLRCQA 240
  241 LNFFPQNITM RWLKDSQPLD AKDVNPENVL PNGDGTYQGW LTLAVAPGEE TRFSCQVEHP 300
  301 GLDQPLTATW EPSRSQDMII GIISGITICA IFFVGILILV LRKRKVSGGT MGDYVLTECE 360
  361

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: HFE_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: