General Information: |
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Name(s) found: |
GHR_RAT
[Swiss-Prot]
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Description(s) found:
SHOW ONLY BEST |
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Organism: | Rattus norvegicus |
Length: | 638 amino acids |
Gene Ontology: |
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Cellular Component: |
receptor complex
[UNKNOWN]
neuronal cell body [IDA] extracellular region [IEA] plasma membrane [UNKNOWN][IDA] cell surface [UNKNOWN][IEA] growth hormone receptor complex [UNKNOWN][IEA] nucleus [UNKNOWN][IDA] integral to plasma membrane [UNKNOWN][IEA] extracellular space [UNKNOWN][IDA] cytoplasm [IDA] mitochondrion [IDA] integral to membrane [UNKNOWN] extrinsic to membrane [UNKNOWN][IEA] |
Biological Process: |
response to food
[IEP]
response to cytokine stimulus [IEP] activation of JAK2 kinase activity [IDA] neuroprotection [IDA] citrate metabolic process [IEA] response to cycloheximide [UNKNOWN] multicellular organismal metabolic process [UNKNOWN][IEA] succinate metabolic process [IEA] creatine metabolic process [IEA] 2-oxoglutarate metabolic process [IEA] positive regulation of multicellular organism growth [UNKNOWN][IEA] allantoin metabolic process [IEA] JAK-STAT cascade [IDA] hormone-mediated signaling pathway [IDA] cellular response to insulin stimulus [IEP] activation of MAPK activity [IDA] response to glucocorticoid stimulus [IEP] positive regulation of peptidyl-tyrosine phosphorylation [IEA] growth hormone receptor signaling pathway [UNKNOWN][IDA] cartilage development involved in endochondral bone morphogenesis [IEP] insulin-like growth factor receptor signaling pathway [UNKNOWN][IEA] positive regulation of cell differentiation [IEP][TAS] valine metabolic process [IEA] response to morphine [IEP] endocytosis [IEA] response to hormone stimulus [IEP] response to peptide hormone stimulus [IEP] fatty acid metabolic process [IEA] positive regulation of JAK-STAT cascade [IDA][IMP] creatinine metabolic process [IEA] isoleucine metabolic process [IEA] oxaloacetate metabolic process [IEA] response to estradiol stimulus [UNKNOWN] response to interleukin-1 [IEP] taurine metabolic process [IEA] cellular response to hormone stimulus [UNKNOWN] [NOT]receptor internalization [UNKNOWN] |
Molecular Function: |
protein kinase binding
[IDA][IPI]
growth factor binding [UNKNOWN] protein binding [UNKNOWN][IEA] protein phosphatase binding [IMP][IPI] protein homodimerization activity [UNKNOWN][IEA] growth hormone receptor activity [UNKNOWN][IDA][TAS] peptide hormone binding [UNKNOWN][IDA] receptor activity [IEA] SH2 domain binding [IDA][IMP][IPI] |
Sequence: |
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Sequence: [PDR BLAST] [ProtParam] |
1 11 21 31 41 51 | | | | | | 1 MDLWRVFLTL ALAVSSDMFP GSGATPATLG KASPVLQRIN PSLRESSSGK PRFTKCRSPE 60 61 LETFSCYWTE GDDHNLKVPG SIQLYYARRI AHEWTPEWKE CPDYVSAGAN SCYFNSSYTS 120 121 IWIPYCIKLT TNGDLLDEKC FTVDEIVQPD PPIGLNWTLL NISLPGIRGD IQVSWQPPPS 180 181 ADVLKGWIIL EYEIQYKEVN ETKWKTMSPI WSTSVPLYSL RLDKEHEVRV RSRQRSFEKY 240 241 SEFSEVLRVT FPQMDTLAAC EEDFRFPWFL IIIFGIFGVA VMLFVVIFSK QQRIKMLILP 300 301 PVPVPKIKGI DPDLLKEGKL EEVNTILGIH DNYKPDFYND DSWVEFIELD IDDADEKTEE 360 361 SDTDRLLSDD QEKSAGILGA KDDDSGRTSC YDPDILDTDF HTSDMCDGTS EFAQPQKLKA 420 421 EADLLCLDQK NLKNSPYDAS LGSLHPSITL TMEDKPQPLL GSETESTHQL PSTPMSSPVS 480 481 LANIDFYAQV SDITPAGGVV LSPGQKIKAG LAQGNTQLEV AAPCQENYSM NSAYFCESDA 540 541 KKCIAAAPHM EATTCVKPSF NQEDIYITTE SLTTTARMSE TADTAPDAEP VPDYTTVHTV 600 601 KSPRGLILNA TALPLPDKKK FLSSCGYVST DQLNKIMQ |
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