Protein Overview: IKBA_RAT

General Information:
Name(s) found:	IKBA_RAT [Swiss-Prot]
Description(s) found: Found 23 descriptions. SHOW ALL	NF-kappa-B inhibitor alpha OS=Rattus norvegicus GN=Nfkbia PE=2 SV=1 [Swiss-Prot]
Organism:	Rattus norvegicus
Length:	314 amino acids
Gene Ontology:
Cellular Component:	nucleus [UNKNOWN][IDA] cytoplasm [UNKNOWN][IDA] cytosol [UNKNOWN][IDA] I-kappaB/NF-kappaB complex [IC] protein complex [IDA]
Biological Process:	positive regulation of cellular protein metabolic process [UNKNOWN][IEA] negative regulation of myeloid cell differentiation [UNKNOWN][IEA] cytoplasmic sequestering of NF-kappaB [UNKNOWN][IMP] negative regulation of NF-kappaB transcription factor activity [UNKNOWN][IEA] response to muramyl dipeptide [UNKNOWN][IEA] toll-like receptor 4 signaling pathway [UNKNOWN][IEA] positive regulation of transcription [UNKNOWN] cytoplasmic sequestering of transcription factor [UNKNOWN] negative regulation of Notch signaling pathway [UNKNOWN][IEA] regulation of cell proliferation [UNKNOWN][IEA] anti-apoptosis [UNKNOWN] nucleotide-binding oligomerization domain containing 2 signaling pathway [UNKNOWN][IEA] response to exogenous dsRNA [UNKNOWN][IEA] protein import into nucleus, translocation [UNKNOWN][IEA] positive regulation of cholesterol efflux [UNKNOWN][IEA] lipopolysaccharide-mediated signaling pathway [UNKNOWN][IEA] negative regulation of macrophage derived foam cell differentiation [UNKNOWN][IEA] negative regulation of lipid storage [UNKNOWN][IEA] response to lipopolysaccharide [UNKNOWN][IEA] positive regulation of gene-specific transcription from RNA polymerase II promoter [UNKNOWN][IEA] nucleotide-binding oligomerization domain containing 1 signaling pathway [UNKNOWN][IEA]
Molecular Function:	NF-kappaB binding [IC][UNKNOWN][IPI] heat shock protein binding [IPI] identical protein binding [UNKNOWN][IEA] protein binding [UNKNOWN] ubiquitin protein ligase binding [UNKNOWN][IEA] protein complex binding [IPI] nuclear localization sequence binding [UNKNOWN][IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFQPAGHGQD WAMEGPRDGL KKERLVDDRH DSGLDSMKDE DYEQMVKELR EIRLQPQEAP  60
   61 LAAEPWKQQL TEDGDSFLHL AIIHEEKTLT MEVIGQVKGD LAFLNFQNNL QQTPLHLAVI 120
  121 TNQPGIAEAL LKAGCDPELR DFRGNTPLHL ACEQGCLASV AVLTQTCTPQ HLHSVLQATN 180
  181 YNGHTCLHLA SIHGYLGIVE HLVTLGADVN AQEPCNGRTA LHLAVDLQNP DLVSLLLKCG 240
  241 ADVNRVTYQG YSPYQLTWGR PSTRIQQQLG QLTLENLQTL PESEDEESYD TESEFTEDEL 300
  301 PYDDCVFGGQ RLTL

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Protein Overview: IKBA_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: