Protein Overview: RHG07_RAT

General Information:
Name(s) found:	RHG07_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|25091121\|sp\|Q63744.3\|RHG07_RAT RecName: Full=Rho GTPase-activating protein 7; AltName: Full=Rho-type GTPase-activating protein 7; AltName: Full=p122-RhoGAP; AltName: Full=Deleted in liver cancer 1 protein homolog; Short=Dlc-1; AltName: Full=StAR-relate [NCBI NR] (Q63744) Rho-GTPase-activating protein 7 (Rho-type GTPase-activating protein 7) (p122-RhoGAP) (Deleted in liver cancer 1 protein homolog) (Dlc-1) (StAR-related lipid transfer protein 12) (StARD12) (START domain-containing protein 12) [Swiss-Prot] Rho GTPase-activating protein 7 OS=Rattus norvegicus GN=Dlc1 PE=1 SV=3 [Swiss-Prot] Ensembl_locations(Chr-bp):16-55436336 Rho-GTPase-activating protein 7 [hmr_yeast5_DM3-1_pombe.fasta] Rho-GTPase-activating protein 7 (Rho-type GTPase-activating protein 7) (p122-RhoGAP) (Deleted in liver cancer 1 protein homolog) (Dlc-1) (StAR-related lipid transfer protein 12) (StARD12) (START domain-containing protein 12) [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Rho-GTPase-activating protein 7 [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] Rho GTPase-activating protein 7 (Rho-type GTPase-activating protein 7) (p122-RhoGAP) (Deleted in liver cancer 1 protein homolog) (Dlc-1) (StAR-related lipid transfer protein 12) (START domain-containing protein 12) (StARD12) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 Gene_Symbol=Dlc1 Rho GTPase-activating protein 7 [rat-ipi-250309-contam.fasta] Rho GTPase-activating protein 7 OS=Rattus norvegicus GN=Dlc1 [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	1091 amino acids
Gene Ontology:
Cellular Component:	nucleus [UNKNOWN][IEA] caveola [UNKNOWN][IEA] focal adhesion [UNKNOWN][IDA] cytoplasm [UNKNOWN][NAS] stress fiber [IDA] membrane raft [IDA] cytosol [IMP] actin filament [IDA] intracellular [IEA]
Biological Process:	regulation of cell shape [UNKNOWN][IEA] negative regulation of Rho protein signal transduction [UNKNOWN][IEA] cytoskeleton organization [IDA][NAS] signal transduction [IEA] negative regulation of cell proliferation [UNKNOWN][ISS] activation of phospholipase C activity [IDA] Rho protein signal transduction [NAS] hindbrain morphogenesis [UNKNOWN][IEA] cellular response to insulin stimulus [IEP] heart morphogenesis [UNKNOWN][IEA] negative regulation of stress fiber assembly [UNKNOWN][IEA] forebrain development [UNKNOWN][IEA] regulation of actin cytoskeleton organization [UNKNOWN][IEA] neural tube closure [UNKNOWN][IEA] induction of apoptosis [UNKNOWN][IEA] positive regulation of protein amino acid dephosphorylation [UNKNOWN][IEA] activation of caspase activity [UNKNOWN][IEA] focal adhesion assembly [UNKNOWN][IEA] actin cytoskeleton organization [UNKNOWN] negative regulation of cell migration [UNKNOWN][IEA]
Molecular Function:	protein binding [UNKNOWN][IDA] GTPase activator activity [IEA] phospholipase binding [IPI] vinculin binding [IPI] Rho GTPase activator activity [UNKNOWN][IDA] [NOT]Rac GTPase activator activity [UNKNOWN] SH2 domain binding [UNKNOWN][IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MCRDEPDTMI LTQIEAKEAC DWLRVTGFPQ YAQLYEDLLF PIDIALVKRE HDFLDRDAIE  60
   61 ALCRRLNTLN KCAVMKLEIS PHRKRSEDSD EEEPCAISGK WTFQRDSKRW SRLEEFDVFS 120
  121 PKQDPIPGSP DNSRLQSATS RESMLTDLSE HQEVSSIRSL SSTSSSAPTH VPHSGEATTP 180
  181 RTNSVISVCS SSHFVGNEDS FSSLPSPKEL SSFSFSMKGH EKNTKSKTRS LLKRMESLKL 240
  241 KGSHHSKHKA PSKLGLIISA PILQEGMDEE KLKQLNCVEI SALNGNHINV PMVRKRSVSN 300
  301 STQTSSSSSQ SETSSAVSTP SPVTRTRSLS TCNKRVGMYL EGFDPFSQSA FNNVTEQNYK 360
  361 NRESYPEDTV FYIPEDHKPG TFPKALSNGS FCPSGNSSVN WRTGSFHGPG HLSLRRENSS 420
  421 DSPKELKRRN SSSSVSSRMS IYDNVPGSIL YSSSGELADL ENEDIFPELD DILYHVKGMQ 480
  481 RIVNQWSEKF SDEGDSDSAL DSVSPCPSSP KQIHLDVDHD RRTPSDLDST GNSLNEPEEP 540
  541 TDIPERRDSG VGASLTRCNR HRLRWHSFQS SHRPSLNSVS LQINCQSVAQ MNLLQKYSLL 600
  601 KLTALLEKYT PSNKHGFSWA VPKFMKRIKV PDYKDRSVFG VPLTVNVQRS GQPLPQSIQQ 660
  661 AMRYLRNHCL DQVGLFRKSG VKSRIQALRQ MNESAEDYVN YEGQSAYDVA DMLKQYFRDL 720
  721 PEPLMTNKLS ETFLQIYQYV PKDQRLQAIK AAIMLLPDEN REVLQTLLYF LSHVTAAVKE 780
  781 NQMTPTNLAV CLAPSLFHLN TLKRENSSPR VMQRKQSLGK PDQKDLNENL AATQGLAHMI 840
  841 AECKKLFQVP EEMSRCRNSY TEQELKPLTL EALGHLSNDQ PADYRHFLQD CVDGLFKEVK 900
  901 EKFKGWVSYP TSEQAELSYK KVSEGPPLRL WRATIEVPAA PEEILKRLLK EQHLWDVDLL 960
  961 DSKVIEILDS QTEIYQYVQN SMAPHPARDY VVLRTWRTNL PRGACALLFT SVDHDRAPVA1020
 1021 GVRVNVLLSR YLIEPCGSGK SKLTYMCRAD LRGHMPEWYT KSFGHLCAAE VVKIRDSFSN1080
 1081 QSTESKDTRS R

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Protein Overview: RHG07_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: