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Protein Overview: SOMA_RAT

General Information:
Name(s) found: SOMA_RAT [Swiss-Prot]
Description(s) found:
Found 20 descriptions.
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  • Somatotropin OS=Rattus norvegicus GN=Gh1 PE=1 SV=1 [Swiss-Prot]
    • Organism: Rattus norvegicus
    Length: 216 amino acids

    Gene Ontology:
    Cellular Component: nucleus [UNKNOWN][IDA]
    extracellular space [UNKNOWN][IDA]
    trans-Golgi network [UNKNOWN][IEA]
    secretory granule [UNKNOWN][IDA]
    mitochondrion [IDA]
    cytosol [IDA]
    extracellular region [IEA]
    cellular_component [ND]
    plasma membrane [UNKNOWN][IEA]
    Biological Process: response to food [UNKNOWN][IEA]
    response to cytokine stimulus [IEP]
    neuroprotection [IDA]
    positive regulation of growth [IMP]
    positive regulation of phosphoinositide 3-kinase cascade [UNKNOWN]
    positive regulation of tyrosine phosphorylation of Stat3 protein [UNKNOWN]
    response to light stimulus [IDA]
    positive regulation of multicellular organism growth [UNKNOWN][IEA]
    JAK-STAT cascade [UNKNOWN]
    positive regulation of insulin-like growth factor receptor signaling pathway [UNKNOWN]
    cellular response to insulin stimulus [UNKNOWN][IEA]
    lung alveolus development [IMP]
    neuroblast proliferation [IDA]
    positive regulation of activation of JAK2 kinase activity [UNKNOWN]
    positive regulation of peptidyl-tyrosine phosphorylation [UNKNOWN]
    growth hormone receptor signaling pathway [UNKNOWN]
    [NOT]positive regulation of receptor internalization [UNKNOWN]
    signal transduction [IDA]
    female pregnancy [IEP]
    positive regulation of cell differentiation [TAS]
    regulation of growth [TAS]
    response to peptide hormone stimulus [IEP]
    positive regulation of tyrosine phosphorylation of Stat5 protein [UNKNOWN]
    positive regulation of JAK-STAT cascade [UNKNOWN]
    response to estradiol stimulus [UNKNOWN]
    glucose transport [UNKNOWN]
    positive regulation of neurogenesis [IDA]
    Molecular Function: growth factor activity [UNKNOWN]
    protein binding [UNKNOWN]
    metal ion binding [IEA]
    growth hormone activity [UNKNOWN]
    growth hormone receptor binding [UNKNOWN][IDA][TAS]
    hormone activity [IDA][TAS]
    prolactin receptor binding [UNKNOWN]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAADSQTPWL LTFSLLCLLW PQEAGAFPAM PLSSLFANAV LRAQHLHQLA ADTYKEFERA  60
   61 YIPEGQRYSI QNAQAAFCFS ETIPAPTGKE EAQQRTDMEL LRFSLLLIQS WLGPVQFLSR 120
  121 IFTNSLMFGT SDRVYEKLKD LEEGIQALMQ ELEDGSPRIG QILKQTYDKF DANMRSDDAL 180
  181 LKNYGLLSCF KKDLHKAETY LRVMKCRRFA ESSCAF

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle