Protein Overview: PTF1A_RAT

General Information:
Name(s) found:	PTF1A_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|81890444\|sp\|Q64305.1\|PTF1A_RAT RecName: Full=Pancreas transcription factor 1 subunit alpha; AltName: Full=Pancreas-specific transcription factor 1a; AltName: Full=bHLH transcription factor p48; AltName: Full=p48 DNA-binding subunit of transcription fac [NCBI NR] pir\|\|S71755 transcription factor PTF1 DNA-binding chain p48 - rat [NCBI NR] gi\|16758982\|ref\|NP_446416.1\| pancreas specific transcription factor, 1a [Rattus norvegicus] [NCBI NR] gi\|149021173\|gb\|EDL78780.1\| pancreas specific transcription factor, 1a [Rattus norvegicus] [NCBI NR] gi\|1430942\|emb\|CAA67076.1\| p48 DNA-binding subunit of transcription factor PTF1 [Rattus norvegicus] [NCBI NR] gi\|1360130\|emb\|CAA66851.1\| transcription factor PTF1 [Rattus norvegicus] [NCBI NR] Pancreas transcription factor 1 subunit alpha OS=Rattus norvegicus GN=Ptf1a PE=1 SV=1 [Swiss-Prot] Ensembl_locations(Chr-bp):17-91125713 P48 DNA-binding subunit of transcription factor PTF1 [hmr_yeast5_DM3-1_pombe.fasta] pancreas specific transcription factor, 1a [HMR_022704-rand.fasta] pancreas specific transcription factor, 1a [Rattus norvegicus]gi\|1430942\|emb\|CAA67076.1\| p48 DNA-binding subunit of transcription factor PTF1 [Rattus norvegicus]gi\|1360130\|emb\|CAA66851.1\| transcription factor PTF1 [Rattus norvegicus]gi\|7514105\|pir\|\|S71 [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Pancreas transcription factor 1 subunit alpha [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] Tax_Id=10116 P48 DNA-binding subunit of transcription factor PTF1 [EBI-IPI_rat_3.13_12-01-2005_con_reversed.fasta] (NM_053964) pancreas specific transcription factor, 1a [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] Pancreas transcription factor 1 subunit alpha (Pancreas-specific transcription factor 1a) (bHLH transcription factor p48) (p48 DNA-binding subunit of transcription factor PTF1) (PTF1-p48) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] pancreas specific transcription factor, 1a [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] p48 DNA-binding subunit of transcription factor PTF1 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] transcription factor PTF1 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 P48 DNA-BINDING SUBUNIT OF TRANSCRIPTION FACTOR PTF1 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=10116 Gene_Symbol=Ptf1a Pancreas transcription factor 1 subunit alpha [rat-ipi-250309-contam.fasta] Pancreas transcription factor 1 subunit alpha OS=Rattus norvegicus GN=Ptf1a [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	326 amino acids
Gene Ontology:
Cellular Component:	nucleus [IDA][TAS] transcription factor complex [UNKNOWN][IDA] cytoplasm [IDA] intracellular [UNKNOWN][IEA]
Biological Process:	embryonic development [ISS] retina morphogenesis in camera-type eye [UNKNOWN][IEA] regulation of transcription, DNA-dependent [UNKNOWN][IDA] positive regulation of transcription [ISS] generation of neurons [ISS] tissue development [UNKNOWN][ISS] retinoic acid receptor signaling pathway [ISS] hindbrain development [ISS] neuron fate commitment [UNKNOWN][IEA] cell fate commitment [UNKNOWN] cell differentiation [UNKNOWN][IEA] exocrine pancreas development [IDA] pancreas development [UNKNOWN]
Molecular Function:	DNA binding [IDA][ISS] transcription factor activity [TAS] protein binding [IEA] sequence-specific DNA binding [UNKNOWN][IEA] transcription activator activity [UNKNOWN][IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDAVLLEHFP GALDTFPSSY FDEEDFFTDQ SSRDPLEDGD ELLGDEQAEV EFLSHQLHEY  60
   61 CYRDGACLLL QPAPSAAPHA LAPPPLGDPG EPEDSGSYCC DAGAPLGAFP YSPGSPPSCL 120
  121 AYPCTAVLSP GTRLRGLNGA AAAAAAAARR RRRVRSEAEL QQLRQAANVR ERRRMQSIND 180
  181 AFEGLRSHIP TLPYEKRLSK VDTLRLAIGY INFLSELVQA DLPLRGSGTG GCGGPGGSRH 240
  241 LGGDSPGNQA QKVIICHRGT RSPSPSDPDY GLPPLAGHSL SWADEKQLKE QNIIRTAKVW 300
  301 TPEDPRKLNS KSFDNIENEP PFEFVS

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Protein Overview: PTF1A_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: