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Protein Overview: ANGT_RAT

General Information:
Name(s) found: ANGT_RAT [Swiss-Prot]
Description(s) found:
Found 21 descriptions.
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  • Angiotensinogen OS=Rattus norvegicus GN=Agt PE=1 SV=1 [Swiss-Prot]
    • Organism: Rattus norvegicus
    Length: 477 amino acids

    Gene Ontology:
    Cellular Component: extracellular space [UNKNOWN][IDA]
    cytoplasmic part [IDA]
    extracellular region [IEA]
    Biological Process: positive regulation of phosphoinositide 3-kinase cascade [UNKNOWN][IEA]
    establishment of blood-nerve barrier [UNKNOWN][IEA]
    cellular sodium ion homeostasis [IMP]
    regulation of norepinephrine secretion [IMP]
    regulation of systemic arterial blood pressure by circulatory renin-angiotensin [UNKNOWN]
    positive regulation of fatty acid biosynthetic process [UNKNOWN][IEA]
    ovarian follicle rupture [UNKNOWN][IEA]
    kidney development [UNKNOWN][IEA]
    negative regulation of cell growth [IMP]
    regulation of long-term neuronal synaptic plasticity [IMP]
    positive regulation of cardiac muscle hypertrophy [IDA]
    natriuresis [IDA][IMP]
    response to muscle activity involved in regulation of muscle adaptation [IMP]
    G-protein coupled receptor protein signaling pathway [UNKNOWN][IMP]
    positive regulation of organ growth [UNKNOWN][IEA]
    excretion [UNKNOWN]
    angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure [UNKNOWN][IEA]
    positive regulation of catalytic activity [IMP]
    renal response to blood flow during renin-angiotensin regulation of systemic arterial blood pressure [UNKNOWN][IEA]
    positive regulation of cellular protein metabolic process [UNKNOWN][IEA]
    drinking behavior [UNKNOWN][IEA]
    response to salt stress [UNKNOWN][IEA]
    negative regulation of cell proliferation [UNKNOWN][IEA]
    positive regulation of epidermal growth factor receptor signaling pathway [UNKNOWN][IEA]
    positive regulation of multicellular organism growth [UNKNOWN][IEA]
    negative regulation of neuron apoptosis [UNKNOWN][IEA]
    smooth muscle cell proliferation [UNKNOWN][IEA]
    response to cold [UNKNOWN][IEA]
    astrocyte activation [UNKNOWN][IEA]
    smooth muscle cell differentiation [UNKNOWN][IEA]
    negative regulation of nerve growth factor receptor signaling pathway [UNKNOWN][IEA]
    renin-angiotensin regulation of aldosterone production [UNKNOWN][IEA]
    blood vessel development [UNKNOWN][IEA]
    regulation of renal output by angiotensin [UNKNOWN][IEA]
    positive regulation of fibroblast proliferation [IDA]
    positive regulation of endothelial cell migration [UNKNOWN][IEA]
    positive regulation of cholesterol esterification [UNKNOWN][IEA]
    positive regulation of peptidyl-tyrosine phosphorylation [UNKNOWN][IEA]
    cell-matrix adhesion [UNKNOWN][IEA]
    activation of phospholipase C activity [IMP]
    cell surface receptor linked signaling pathway [IDA]
    positive regulation of MAPKKK cascade [UNKNOWN][IEA]
    regulation of blood pressure [UNKNOWN][IEP]
    hormone metabolic process [UNKNOWN][IEA]
    brain renin-angiotensin system [UNKNOWN][IEA]
    [NOT]branching involved in ureteric bud morphogenesis [UNKNOWN][IEA]
    positive regulation of apoptosis [UNKNOWN][IEA]
    extracellular matrix organization [UNKNOWN][IEA]
    peristalsis [UNKNOWN][IEA]
    Molecular Function: type 2 angiotensin receptor binding [UNKNOWN][IMP]
    serine-type endopeptidase inhibitor activity [IEA]
    angiotensin receptor binding [IMP]
    type 1 angiotensin receptor binding [UNKNOWN][IMP]
    alpha1-adrenergic receptor activity [TAS]
    acetyltransferase activator activity [UNKNOWN][IEA]
    hormone activity [IDA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTPTGAGLKA TIFCILTWVS LTAGDRVYIH PFHLLYYSKS TCAQLENPSV ETLPEPTFEP  60
   61 VPIQAKTSPV DEKTLRDKLV LATEKLEAED RQRAAQVAMI ANFMGFRMYK MLSEARGVAS 120
  121 GAVLSPPALF GTLVSFYLGS LDPTASQLQV LLGVPVKEGD CTSRLDGHKV LTALQAVQGL 180
  181 LVTQGGSSSQ TPLLQSTVVG LFTAPGLRLK QPFVESLGPF TPAIFPRSLD LSTDPVLAAQ 240
  241 KINRFVQAVT GWKMNLPLEG VSTDSTLFFN TYVHFQGKMR GFSQLTGLHE FWVDNSTSVS 300
  301 VPMLSGTGNF QHWSDAQNNF SVTRVPLGES VTLLLIQPQC ASDLDRVEVL VFQHDFLTWI 360
  361 KNPPPRAIRL TLPQLEIRGS YNLQDLLAQA KLSTLLGAEA NLGKMGDTNP RVGEVLNSIL 420
  421 LELQAGEEEQ PTESAQQPGS PEVLDVTLSS PFLFAIYERD SGALHFLGRV DNPQNVV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle