Protein Overview: TRPV1_RAT

General Information:
Name(s) found:	TRPV1_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	pir\|\|T09054 capsaicin receptor - rat [NCBI NR] gi\|71164787\|sp\|O35433.1\|TRPV1_RAT RecName: Full=Transient receptor potential cation channel subfamily V member 1; Short=TrpV1; AltName: Full=Osm-9-like TRP channel 1; Short=OTRPC1; AltName: Full=Vanilloid receptor 1; AltName: Full=Vanilloid receptor type [NCBI NR] gi\|2570933\|gb\|AAC53398.1\| vanilloid receptor subtype 1 [Rattus norvegicus] [NCBI NR] gi\|149053329\|gb\|EDM05146.1\| rCG32926, isoform CRA_b [Rattus norvegicus] [NCBI NR] gi\|14010883\|ref\|NP_114188.1\| transient receptor potential cation channel, subfamily V, member 1 [Rattus norvegicus] [NCBI NR] Transient receptor potential cation channel subfamily V member 1 OS=Rattus norvegicus GN=Trpv1 PE=1 SV=1 [Swiss-Prot] Ensembl_locations(Chr-bp):10-58609318 Vanilloid receptor subtype 1 [hmr_yeast5_DM3-1_pombe.fasta] vanilloid receptor type 1 like protein 1 [HMR_022704-rand.fasta] vanilloid receptor type 1 like protein 1 [Rattus norvegicus]gi\|7513930\|pir\|\|T09054 capsaicin receptor - ratgi\|2570933\|gb\|AAC53398.1\| vanilloid receptor subtype 1 [Rattus norvegicus] [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Splice Isoform 1 of Transient receptor potential cation channel subfamily V member 1 [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] (NM_031982) vanilloid receptor type 1 like protein 1 [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] Tax_Id=10116 Vanilloid receptor subtype 1 [EBI-IPI_rat_3.05_04-04-2005_origrev.fasta] transient receptor potential cation channel, subfamily V, member 1 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Transient receptor potential cation channel subfamily V member 1 (TrpV1) (osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1) (Vanilloid receptor type 1-like) (Capsaicin receptor) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] rCG32926, isoform CRA_b [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] vanilloid receptor subtype 1 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 VANILLOID RECEPTOR SUBTYPE 1 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] vanilloid receptor type 1 like protein 1 [Rattus norvegicus] [nr-271106-contam.fasta] Tax_Id=10116 Gene_Symbol=Trpv1 Isoform 1 of Transient receptor potential cation channel subfamily V member 1 [rat-ipi-250309-contam.fasta] Isoform 1 of Transient receptor potential cation channel subfamily V member 1 OS=Rattus norvegicus GN=Trpv1 [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	838 amino acids
Gene Ontology:
Cellular Component:	dendrite [IDA] membrane [IDA] integral to membrane [UNKNOWN][IEA] cytosol [IDA] neuronal cell body [IDA] synapse [IDA] neuron projection [UNKNOWN] plasma membrane [IDA]
Biological Process:	glutamate secretion [IDA] catagen [UNKNOWN][IEA] positive regulation of nitric oxide biosynthetic process [IMP] negative regulation of establishment of blood-brain barrier [IMP] diet induced thermogenesis [UNKNOWN][IEA] response to pain [UNKNOWN] ion transport [IEA] response to heat [UNKNOWN][IDA] calcium ion transport [UNKNOWN][IEA] behavioral response to pain [UNKNOWN][IEA] thermoception [UNKNOWN] urinary bladder smooth muscle contraction [UNKNOWN] sensory perception of mechanical stimulus [UNKNOWN][IEA] positive regulation of gastric acid secretion [IMP] response to chemical stimulus [UNKNOWN][IEA] peptide secretion [UNKNOWN][IEA] response to pH [UNKNOWN][IDA][IEP] fever [UNKNOWN][IEA] response to peptide hormone stimulus [IEP] elevation of cytosolic calcium ion concentration [IDA] microglial cell activation [IMP] cellular response to growth factor stimulus [IEP] temperature homeostasis [UNKNOWN][IEA] lipid metabolic process [UNKNOWN][IEA] positive regulation of apoptosis [IMP] detection of chemical stimulus involved in sensory perception of pain [UNKNOWN][IEA] sensory perception of pain [UNKNOWN] cellular response to temperature stimulus [IEP] smooth muscle contraction involved in micturition [UNKNOWN][IEA]
Molecular Function:	nucleotide binding [IEA] ion channel activity [UNKNOWN] ATP binding [IEA] chloride channel regulator activity [IDA] calmodulin binding [IEA] protein binding [IPI] calcium channel activity [UNKNOWN][IEA] cation channel activity [IDA] cation transmembrane transporter activity [IDA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEQRASLDSE ESESPPQENS CLDPPDRDPN CKPPPVKPHI FTTRSRTRLF GKGDSEEASP  60
   61 LDCPYEEGGL ASCPIITVSS VLTIQRPGDG PASVRPSSQD SVSAGEKPPR LYDRRSIFDA 120
  121 VAQSNCQELE SLLPFLQRSK KRLTDSEFKD PETGKTCLLK AMLNLHNGQN DTIALLLDVA 180
  181 RKTDSLKQFV NASYTDSYYK GQTALHIAIE RRNMTLVTLL VENGADVQAA ANGDFFKKTK 240
  241 GRPGFYFGEL PLSLAACTNQ LAIVKFLLQN SWQPADISAR DSVGNTVLHA LVEVADNTVD 300
  301 NTKFVTSMYN EILILGAKLH PTLKLEEITN RKGLTPLALA ASSGKIGVLA YILQREIHEP 360
  361 ECRHLSRKFT EWAYGPVHSS LYDLSCIDTC EKNSVLEVIA YSSSETPNRH DMLLVEPLNR 420
  421 LLQDKWDRFV KRIFYFNFFV YCLYMIIFTA AAYYRPVEGL PPYKLKNTVG DYFRVTGEIL 480
  481 SVSGGVYFFF RGIQYFLQRR PSLKSLFVDS YSEILFFVQS LFMLVSVVLY FSQRKEYVAS 540
  541 MVFSLAMGWT NMLYYTRGFQ QMGIYAVMIE KMILRDLCRF MFVYLVFLFG FSTAVVTLIE 600
  601 DGKNNSLPME STPHKCRGSA CKPGNSYNSL YSTCLELFKF TIGMGDLEFT ENYDFKAVFI 660
  661 ILLLAYVILT YILLLNMLIA LMGETVNKIA QESKNIWKLQ RAITILDTEK SFLKCMRKAF 720
  721 RSGKLLQVGF TPDGKDDYRW CFRVDEVNWT TWNTNVGIIN EDPGNCEGVK RTLSFSLRSG 780
  781 RVSGRNWKNF ALVPLLRDAS TRDRHATQQE EVQLKHYTGS LKPEDAEVFK DSMVPGEK

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: TRPV1_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: