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Protein Overview: BOK_RAT

General Information:
Name(s) found: BOK_RAT [Swiss-Prot]
Description(s) found:
Found 19 descriptions.
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  • Bcl-2-related ovarian killer protein OS=Rattus norvegicus GN=Bok PE=2 SV=1 [Swiss-Prot]
    • Organism: Rattus norvegicus
    Length: 213 amino acids

    Gene Ontology:
    Cellular Component: cellular_component [ND]
    Biological Process: induction of apoptosis [UNKNOWN][IEA]
    apoptosis [UNKNOWN][IDA]
    positive regulation of apoptosis [IDA]
    Molecular Function: BH domain binding [IPI]
    protein heterodimerization activity [IPI]
    protein dimerization activity [IPI]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEVLRRSSVF AAEIMDAFDR SPTDKELVAQ AKALGREYVH ARLLRAGLSW SAPERASPAP  60
   61 GGRLAEVCTV LLRLGDELEQ IRPSVYRNVA RQLHIPLQSE PVVTDAFLAV AGHIFSAGIT 120
  121 WGKVVSLYSV AAGLAVDCVR QAQPAMVHAL VDCLGEFVRK TLATWLRRRG GWTDVLKCVV 180
  181 STDPGFRSHW LVATLCSFGR FLKAAFFLLL PER

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..213] PSI-BLAST 45.69897 Solution structure of the anti-apoptotic protein Bcl-2 complexed with an acyl-sulfonamide-based ligand

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • protein binding
    		•  2.78803636113333 bayes_pls_golite062009
  • binding
    		•  2.12358089265543 bayes_pls_golite062009
  • protein dimerization activity
    		•  1.64504453561047 bayes_pls_golite062009
  • protein heterodimerization activity
    		•  1.52306670675388 bayes_pls_golite062009
  • death domain binding
    		•  0.807539351618739 bayes_pls_golite062009
  • identical protein binding
    		•  0.488482699265135 bayes_pls_golite062009
  • BH3 domain binding
    		•  0.351738412090861 bayes_pls_golite062009
  • BH domain binding
    		•  0.173539163685055 bayes_pls_golite062009
  • caspase regulator activity
    		•  0.0685275773265202 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.41

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle