Protein Overview: SCN3A_RAT

General Information:
Name(s) found:	SCN3A_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	pir\|\|S00320 sodium channel protein III - rat [NCBI NR] gi\|6981510\|ref\|NP_037251.1\| sodium channel, voltage-gated, type III, alpha [Rattus norvegicus] [NCBI NR] gi\|57211\|emb\|CAA68735.1\| unnamed protein product [Rattus norvegicus] [NCBI NR] gi\|116449\|sp\|P08104.1\|SCN3A_RAT RecName: Full=Sodium channel protein type 3 subunit alpha; AltName: Full=Sodium channel protein type III subunit alpha; AltName: Full=Voltage-gated sodium channel subunit alpha Nav1.3; AltName: Full=Sodium channel protein, [NCBI NR] Sodium channel protein type 3 subunit alpha OS=Rattus norvegicus GN=Scn3a PE=1 SV=1 [Swiss-Prot] (P08104) Sodium channel protein type III alpha subunit (Voltage-gated sodium channel alpha subunit Nav1.3) (Sodium channel protein, brain III alpha subunit) (Voltage-gated sodium channel subtype III) [Swiss-Prot] Ensembl_locations(Chr-bp):3-46921187 Sodium channel protein, brain III alpha subunit [hmr_yeast5_DM3-1_pombe.fasta] sodium channel, voltage-gated, type III, alpha polypeptide [HMR_022704-rand.fasta] sodium channel, voltage-gated, type III, alpha polypeptide [Rattus norvegicus]gi\|57211\|emb\|CAA68735.1\| unnamed protein product [Rattus norvegicus]gi\|92754\|pir\|\|S00320 sodium channel protein III - ratgi\|116449\|sp\|P08104\|CIN3_RAT Sodium channel protein t [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Sodium channel protein type 3 alpha subunit [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] Tax_Id=10116 Sodium channel protein type III alpha subunit [EBI-IPI_rat_3.13_12-01-2005_con_reversed.fasta] (NM_013119) sodium channel, voltage-gated, type III, alpha polypeptide [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] Sodium channel protein type 3 subunit alpha (Sodium channel protein type III subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.3) (Sodium channel protein, brain III subunit alpha) (Voltage-gated sodium channel subtype III) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] sodium channel, voltage-gated, type III, alpha [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] unnamed protein product [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 SODIUM CHANNEL PROTEIN TYPE III ALPHA SUBUNIT [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] sodium channel, voltage-gated, type III, alpha polypeptide [Rattus norvegicus] [nr-271106-contam.fasta] Tax_Id=10116 Gene_Symbol=Scn3a Sodium channel protein type 3 subunit alpha [rat-ipi-250309-contam.fasta] Sodium channel protein type 3 subunit alpha OS=Rattus norvegicus GN=Scn3a [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	1951 amino acids
Gene Ontology:
Cellular Component:	membrane fraction [UNKNOWN] cytoplasm [UNKNOWN] membrane [IEA] integral to membrane [IEA] voltage-gated sodium channel complex [IDA][TAS] neuronal cell body [IDA] axon [IDA]
Biological Process:	sodium ion transport [IEA] ion transport [IEA] transmembrane transport [IEA] response to pyrethroid [IDA] nervous system development [IEP] response to wounding [IEP] sensory perception of pain [IMP] cellular response to antibiotic [IDA] regulation of action potential in neuron [IDA]
Molecular Function:	calmodulin binding [IDA] protein binding [IPI] voltage-gated ion channel activity [IEA] sodium ion binding [IDA] voltage-gated sodium channel activity [IDA][TAS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAQALLVPPG PESFRLFTRE SLAAIEKRAA EEKAKKPKKE QDIDDENKPK PNSDLEAGKN  60
   61 LPFIYGDIPP EMVSEPLEDL DPYYVSKKTF VVLNKGKAIF RFSATSALYI LTPLNPVRKI 120
  121 AIKILVHSLF SMLIMCTILT NCVFMTLSNP PDWTKNVEYT FTGIYTFESL IKILARGFCL 180
  181 EDFTFLRDPW NWLDFSVIVM AYVTEFVDLG NVSALRTFRV LRALKTISVI PGLKTIVGAL 240
  241 IQSVKKLSDV MILTVFCLSV FALIGLQLFM GNLRNKCSQW PPSDSAFETN TTSYFNGTMD 300
  301 SNGTFVNVTM STFNWKDYIA DDSHFYVLDG QKDPLLCGNG SDAGQCPEGY ICVKAGRNPN 360
  361 YGYTSFDTFS WAFLSLFRLM TQDYWENLYQ LTLRAAGKTY MIFFVLVIFL GSFYLVNLIL 420
  421 AVVAMAYEEQ NQATLEEAEQ KEAEFQQMLE QLKKQQEEAQ AVAAASAASR DFSGIGGLGE 480
  481 LLESSSEASK LSSKSAKEWR NRRKKRRQRE HLEGNHRADG DRFPKSESED SVKRRSFLLS 540
  541 LDGNPLTGDK KLCSPHQSLL SIRGSLFSPR RNSKTSIFSF RGRAKDVGSE NDFADDEHST 600
  601 FEDSESRRDS LFVPHRPGER RNSNGTTTET EVRKRRLSSY QISMEMLEDS SGRQRSMSIA 660
  661 SILTNTMEEL EESRQKCPPC WYRFANVFLI WDCCDAWLKV KHLVNLIVMD PFVDLAITIC 720
  721 IVLNTLFMAM EHYPMTQQFS SVLTVGNLVF TGIFTAEMVL KIIAMDPYYY FQEGWNIFDG 780
  781 IIVSLSLMEL GLANVEGLSV LRSFRLLRVF KLAKSWPTLN MLIKIIGNSV GALGNLTLVL 840
  841 AIIVFIFAVV GMQLFGKSYK ECVCKINVDC KLPRWHMNDF FHSFLIVFRV LCGEWIETMW 900
  901 DCMEVAGQTM CLIVFMLVMV IGNLVVLNLF LALLLSSFSS DNLAATDDDN EMNNLQIAVG 960
  961 RMQKGIDFVK NKIRECFRKA FFRKPKVIEI QEGNKIDSCM SNNTGIEISK ELNYLKDGNG1020
 1021 TTSGVGTGSS VEKYVIDEND YMSFINNPSL TVTVPIAVGE SDFENLNTEE FSSESELEES1080
 1081 KEKLNATSSS EGSTVDVAPP REGEQAEIEP EEDLKPEACF TEGCIKKFPF CQVSTEEGKG1140
 1141 KIWWNLRKTC YSIVEHNWFE TFIVFMILLS SGALAFEDIY IEQRKTIKTM LEYADKVFTY1200
 1201 IFILEMLLKW VAYGFQTYFT NAWCWLDFLI VDVSLVSLVA NALGYSELGA IKSLRTLRAL1260
 1261 RPLRALSRFE GMRVVVNALV GAIPSIMNVL LVCLIFWLIF SIMGVNLFAG KFYHCVNTTT1320
 1321 GNMFEIKEVN NFSDCQALGK QARWKNVKVN FDNVGAGYLA LLQVATFKGW MDIMYAAVDS1380
 1381 RDVKLQPIYE ENLYMYLYFV IFIIFGSFFT LNLFIGVIID NFNQQKKKFG GQDIFMTEEQ1440
 1441 KKYYNAMKKL GSKKPQKPIP RPANKFQGMV FDFVTRQVFD ISIMILICLN MVTMMVETDD1500
 1501 QSKYMTLVLS RINLVFIVLF TGEFLLKLIS LRYYYFTIGW NIFDFVVVIL SIVGMFLAEL1560
 1561 IEKYFVSPTL FRVIRLARIG RILRLIKGAK GIRTLLFALM MSLPALFNIG LLLFLVMFIY1620
 1621 AIFGMSNFAY VKKEAGIDDM FNFETFGNSM ICLFQITTSA GWDGLLAPIL NSAPPDCDPD1680
 1681 AIHPGSSVKG DCGNPSVGIF FFVSYIIISF LVVVNMYIAV ILENFSVATE ESAEPLSEDD1740
 1741 FEMFYEVWEK FDPDATQFIE FCKLSDFAAA LDPPLLIAKP NKVQLIAMDL PMVSGDRIHC1800
 1801 LDILFAFTKR VLGESGEMDA LRIQMEDRFM ASNPSKVSYE PITTTLKRKQ EEVSAAIIQR1860
 1861 NYRCYLLKQR LKNISSKYDK ETIKGRIDLP IKGDMVIDKL NGNSTPEKTD GSSSTTSPPS1920
 1921 YDSVTKPDKE KFEKDKPEKE IKGKEVRENQ K

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: SCN3A_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: