Protein Overview: NR1H2_RAT

General Information:
Name(s) found:	NR1H2_RAT [Swiss-Prot]
Description(s) found: Found 16 descriptions. SHOW ALL	Oxysterols receptor LXR-beta OS=Rattus norvegicus GN=Nr1h2 PE=2 SV=1 [Swiss-Prot]
Organism:	Rattus norvegicus
Length:	446 amino acids
Gene Ontology:
Cellular Component:	nucleus [UNKNOWN][IEA] cytoplasm [UNKNOWN][IEA]
Biological Process:	positive regulation of cellular protein metabolic process [UNKNOWN][IEA] lipid homeostasis [IEA] regulation of transcription, DNA-dependent [UNKNOWN] cellular lipid metabolic process [UNKNOWN][IEA] negative regulation of proteolysis [IEA] cholesterol homeostasis [IEA] regulation of transcription from RNA polymerase II promoter [UNKNOWN][IEA] positive regulation of fatty acid biosynthetic process [UNKNOWN][IEA] negative regulation of pinocytosis [UNKNOWN][IEA] retinoic acid receptor signaling pathway [IPI] positive regulation of triglyceride biosynthetic process [UNKNOWN][IEA] positive regulation of transcription, DNA-dependent [IMP] negative regulation of transcription [UNKNOWN][IEA] positive regulation of cholesterol efflux [UNKNOWN][IEA] negative regulation of cholesterol storage [UNKNOWN][IEA] positive regulation of cholesterol transport [UNKNOWN] positive regulation of gene-specific transcription from RNA polymerase II promoter [UNKNOWN][IEA] positive regulation of lipid storage [IEA] positive regulation of lipoprotein lipase activity [UNKNOWN][IEA] positive regulation of high-density lipoprotein particle assembly [IEA] negative regulation of gene-specific transcription from RNA polymerase II promoter [IEA] negative regulation of lipid transport [UNKNOWN][IEA]
Molecular Function:	DNA binding [UNKNOWN][IDA] transcription factor activity [UNKNOWN][IEA] zinc ion binding [IEA] protein binding [UNKNOWN][IEA] ligand-dependent nuclear receptor activity [UNKNOWN] metal ion binding [IEA] steroid hormone receptor activity [IEA] sequence-specific DNA binding [IEA] transcription activator activity [IMP] retinoid X receptor binding [UNKNOWN][IDA][IPI]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSPTSSLDT PLPGNGSPQP STSSTSPTIK EEGQETDPPP GSEGSSSAYI VVILEPEDEP  60
   61 ERKRKKGPAP KMLGHELCRV CGDKASGFHY NVLSCEGCKG FFRRSVVHGG AGRYACRGSG 120
  121 TCQMDAFMRR KCQLCRLRKC KEAGMREQCV LSEEQIRKKK IQKQQQQQPP PPTEPASGSS 180
  181 ARPAASPGTS EASSQGSGEG EGIQLTAAQE LMIQQLVAAQ LQCNKRSFSD QPKVTPWPLG 240
  241 ADPQSRDARQ QRFAHFTELA IISVQEIVDF AKQVPGFLQL GREDQIALLK ASTIEIMLLE 300
  301 TARRYNHETE CITFLKDFTY SKDDFHRAGL QVEFINPIFE FSRAMRRLGL DDAEYALLIA 360
  361 INIFSADRPN VQEPSRVEAL QQPYVEALLS YTRIKRPQDQ LRFPRMLMKL VSLRTLSSVH 420
  421 SEQVFALRLQ DKKLPPLLSE IWDVHE

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.98

Protein Overview: NR1H2_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: