General Information: |
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Name(s) found: |
NR1H2_RAT
[Swiss-Prot]
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Description(s) found:
SHOW ONLY BEST |
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Organism: | Rattus norvegicus |
Length: | 446 amino acids |
Gene Ontology: |
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Cellular Component: |
nucleus
[UNKNOWN][IEA]
cytoplasm [UNKNOWN][IEA] |
Biological Process: |
positive regulation of cellular protein metabolic process
[UNKNOWN][IEA]
lipid homeostasis [IEA] regulation of transcription, DNA-dependent [UNKNOWN] cellular lipid metabolic process [UNKNOWN][IEA] negative regulation of proteolysis [IEA] cholesterol homeostasis [IEA] regulation of transcription from RNA polymerase II promoter [UNKNOWN][IEA] positive regulation of fatty acid biosynthetic process [UNKNOWN][IEA] negative regulation of pinocytosis [UNKNOWN][IEA] retinoic acid receptor signaling pathway [IPI] positive regulation of triglyceride biosynthetic process [UNKNOWN][IEA] positive regulation of transcription, DNA-dependent [IMP] negative regulation of transcription [UNKNOWN][IEA] positive regulation of cholesterol efflux [UNKNOWN][IEA] negative regulation of cholesterol storage [UNKNOWN][IEA] positive regulation of cholesterol transport [UNKNOWN] positive regulation of gene-specific transcription from RNA polymerase II promoter [UNKNOWN][IEA] positive regulation of lipid storage [IEA] positive regulation of lipoprotein lipase activity [UNKNOWN][IEA] positive regulation of high-density lipoprotein particle assembly [IEA] negative regulation of gene-specific transcription from RNA polymerase II promoter [IEA] negative regulation of lipid transport [UNKNOWN][IEA] |
Molecular Function: |
DNA binding
[UNKNOWN][IDA]
transcription factor activity [UNKNOWN][IEA] zinc ion binding [IEA] protein binding [UNKNOWN][IEA] ligand-dependent nuclear receptor activity [UNKNOWN] metal ion binding [IEA] steroid hormone receptor activity [IEA] sequence-specific DNA binding [IEA] transcription activator activity [IMP] retinoid X receptor binding [UNKNOWN][IDA][IPI] |
Sequence: |
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Sequence: [PDR BLAST] [ProtParam] |
1 11 21 31 41 51 | | | | | | 1 MSSPTSSLDT PLPGNGSPQP STSSTSPTIK EEGQETDPPP GSEGSSSAYI VVILEPEDEP 60 61 ERKRKKGPAP KMLGHELCRV CGDKASGFHY NVLSCEGCKG FFRRSVVHGG AGRYACRGSG 120 121 TCQMDAFMRR KCQLCRLRKC KEAGMREQCV LSEEQIRKKK IQKQQQQQPP PPTEPASGSS 180 181 ARPAASPGTS EASSQGSGEG EGIQLTAAQE LMIQQLVAAQ LQCNKRSFSD QPKVTPWPLG 240 241 ADPQSRDARQ QRFAHFTELA IISVQEIVDF AKQVPGFLQL GREDQIALLK ASTIEIMLLE 300 301 TARRYNHETE CITFLKDFTY SKDDFHRAGL QVEFINPIFE FSRAMRRLGL DDAEYALLIA 360 361 INIFSADRPN VQEPSRVEAL QQPYVEALLS YTRIKRPQDQ LRFPRMLMKL VSLRTLSSVH 420 421 SEQVFALRLQ DKKLPPLLSE IWDVHE |
NOT SHOWING SINGLE HITS. [ Show Single Hits ]
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Protein predicted to be: | GLOBULAR (No transmembrane regions or signal peptide) |
Confidence of classification: | 0.98 |
Source: Reynolds et al. (2008)