Protein Overview: NFKB1_RAT

General Information:
Name(s) found:	NFKB1_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|474298\|gb\|AAA20684.1\| nuclear factor kappa B [NCBI NR] gi\|2500134\|sp\|Q63369.1\|NFKB1_RAT RecName: Full=Nuclear factor NF-kappa-B p105 subunit; AltName: Full=DNA-binding factor KBF1; AltName: Full=EBP-1; Contains: RecName: Full=Nuclear factor NF-kappa-B p50 subunit [NCBI NR] pir\|\|I67414 nuclear factor kappa B - rat (fragment) [NCBI NR] Nuclear factor NF-kappa-B p105 subunit (Fragment) OS=Rattus norvegicus GN=Nfkb1 PE=1 SV=1 [Swiss-Prot] (Q63369) Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP-1) [Contains: Nuclear factor NF-kappa-B p50 subunit] (Fragment) [Swiss-Prot] Ensembl_locations(Chr-bp):None Nuclear factor NF-kappa-B p105 subunit [hmr_yeast5_DM3-1_pombe.fasta] Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP-1) [Contains: Nuclear factor NF-kappa-B p50 subunit]gi\|2143883\|pir\|\|I67414 nuclear factor kappa B - rat (fragment)gi\|474298\|gb\|AAA20684.1\| nuclear factor kappa B [nrdb_11152004_Chlamydomonas] Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP-1) [Contains: Nuclear factor NF-kappa-B p50 subunit] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] nuclear factor kappa B [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Nuclear factor NF-kappa-B p105 subunit (Fragment) OS=Rattus norvegicus GN=Nfkb1 [011711_HMR.fasta] Nuclear factor NF-kappa-B p105 subunit (Fragment) OS=Rattus norvegicus GN=Nfkb1 PE=2 SV=1 [UNIPROT_RAT_07-21-2011_reversed.fasta]
Organism:	Rattus norvegicus
Length:	522 amino acids
Gene Ontology:
Cellular Component:	nucleus [UNKNOWN][IDA][IEA][TAS] cytoplasm [UNKNOWN][IDA] cytosol [UNKNOWN][IDA] protein complex [IDA] nucleoplasm [UNKNOWN]
Biological Process:	signal transduction [IEA] membrane protein intracellular domain proteolysis [UNKNOWN] response to copper ion [IEP] regulation of transcription, DNA-dependent [IEA] regulation of transcription [IEA] positive regulation of transcription from RNA polymerase II promoter [UNKNOWN][IDA] response to oxidative stress [IDA] negative regulation of interleukin-12 biosynthetic process [UNKNOWN][IEA] anti-apoptosis [UNKNOWN][IMP] negative regulation of calcidiol 1-monooxygenase activity [UNKNOWN] negative regulation of transcription, DNA-dependent [UNKNOWN][IEA] negative regulation of cytokine production [IEA] positive regulation of gene-specific transcription from RNA polymerase II promoter [UNKNOWN][IEA]
Molecular Function:	DNA binding [UNKNOWN] heat shock protein binding [IPI] transcription factor activity [IEA][TAS] protein binding [UNKNOWN][IPI][TAS] protein homodimerization activity [UNKNOWN][IEA] actin binding [IPI] double-stranded DNA binding [IDA] sequence-specific DNA binding [IDA] protein dimerization activity [IDA] promoter binding [UNKNOWN] transcription activator activity [IDA] specific transcriptional repressor activity [UNKNOWN][IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 REILNPPEKE TQGEGPSLFM ASTKTEAIAP ASTMEDKEED VGFQDNLFLE KALQLAKRHA  60
   61 NALFDYAVTG DVKMLLAVQR HLTAVQDENG DSVLHLAIIH LHAQLVRDLL EVTSGSISDD 120
  121 IINMRNDLYQ TPLHLAVITK QEDVVEDLLR VGADLSLLDR WGNSVLHLAA KEGHDKILGV 180
  181 LLKNSKAALL INHPNGEGLN AIHIAVMSNS LSCLQLLVAA GAEVNAQEQK SGRTALHLAV 240
  241 EYDNISLAGC LLLEGDALVD STTYDGTTPL HIAAGRGSTR LAALLKAAGA DPLVENFEPL 300
  301 YDLDDSWEKA GEDEGVVPGT TPLDMAANWQ VFDILNGKPY EPVFTSDDIL PQGDIKQLTE 360
  361 DTRLQLCKLL EIPDPDKNWA TLAQKLGLGI LNNAFRLSPA PSKTLMDNYE VSGGTIKELV 420
  421 EALRQMGYTE AIEVIQAAFR TPETTASSPV TTAQAHLLPL SSSSTRQHID ELRDNDSVCD 480
  481 SGVETSFRKL SFSESLTGDG PLLSLNKMPH NYGQDGPIEG KI

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.98

Protein Overview: NFKB1_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: