Protein Overview: CLCN3_RAT

General Information:
Name(s) found:	CLCN3_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|4762023\|gb\|AAD29440.1\|AF142778_1 chloride channel protein 3 long form [Rattus norvegicus] [NCBI NR] gi\|226693515\|sp\|P51792.2\|CLCN3_RAT RecName: Full=H(+)/Cl(-) exchange transporter 3; AltName: Full=Chloride transporter ClC-3; Short=ClC-3; AltName: Full=Chloride channel protein 3 [NCBI NR] gi\|149032291\|gb\|EDL87197.1\| chloride channel 3, isoform CRA_c [Rattus norvegicus] [NCBI NR] gi\|148298669\|ref\|NP_445815.2\| chloride channel 3 [Rattus norvegicus] [NCBI NR] H(+)/Cl(-) exchange transporter 3 OS=Rattus norvegicus GN=Clcn3 PE=2 SV=2 [Swiss-Prot] Ensembl_locations(Chr-bp):16-30689179 Chloride channel protein 3 long form [hmr_yeast5_DM3-1_pombe.fasta] chloride channel protein 3 long form [Rattus norvegicus] [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Chloride channel protein 3 long form (Fragment) [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] Tax_Id=10116 Chloride channel protein 3 long form [EBI-IPI_rat_3.13_12-01-2005_con_reversed.fasta] chloride channel 3 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] chloride channel 3, isoform CRA_c [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 Gene_Symbol=Clcn3 Chloride channel protein 3 long form (Fragment) [rat-ipi-250309-contam.fasta] Isoform 1 of H(+)/Cl(-) exchange transporter 3 OS=Rattus norvegicus GN=Clcn3 [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	818 amino acids
Gene Ontology:
Cellular Component:	late endosome [UNKNOWN][ISS] Golgi apparatus [UNKNOWN][ISS] intracellular [IDA] plasma membrane [IDA] early endosome membrane [IEA] late endosome membrane [IEA] early endosome [UNKNOWN][ISS] transport vesicle membrane [IEA] vesicle membrane [UNKNOWN][ISS] membrane [IDA][IEA] integral to membrane [IDA] cytoplasmic vesicle [IEA] apical plasma membrane [IDA]
Biological Process:	ion transport [IDA] transmembrane transport [IEA] chloride transport [IDA][IEA]
Molecular Function:	nucleotide binding [IEA] ion channel activity [IDA][IEA] ATP binding [IEA] protein binding [UNKNOWN] antiporter activity [IEA] protein heterodimerization activity [UNKNOWN] PDZ domain binding [UNKNOWN][ISS] voltage-gated ion channel activity [IDA] chloride channel activity [IDA] voltage-gated chloride channel activity [IDA][IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MESEQLFHRG YYRNSYNSIT SASSDEELLD GAGAIMDFQT SEDDNLLDGD TAAGTHYTMT  60
   61 NGGSINSSTH LLDLLDEPIP GVGTYDDFHT IDWVREKCKD RERHRRINSK KKESAWEMTK 120
  121 SLYDAWSGWL VVTLTGLASG ALAGLIDIAA DWMTDLKEGI CLSALWYNHE QCCWGSNETT 180
  181 FEERDKCPQW KTWAELIIGQ AEGPGSYIMN YIMYIFWALS FAFLAVSLVK VFAPYACGSG 240
  241 IPEIKTILSG FIIRGYLGKW TLMIKTITLV LAVASGLSLG KEGPLVHVAC CCGNIFSYLF 300
  301 PKYSTNEAKK REVLSAASAA GVSVAFGAPI GGVLFSLEEV SYYFPLKTLW RSFFAALVAA 360
  361 FVLRSINPFG NSRLVLFYVE YHTPWYLFEL FPFILLGVFG GLWGAFFIRA NIAWCRRRKS 420
  421 TKFGKYPVLE VIIVAAITAV IAFPNPYTRL NTSELIKELF TDCGPLESSS LCDYRNDMNA 480
  481 SKIVDDIPDR PAGVGVYSAI WQLCLALIFK IIMTVFTFGI KVPSGLFIPS MAIGAIAGRI 540
  541 VGIAVEQLAY YHHDWFIFKE WCEVGADCIT PGLYAMVGAA ACLGGVTRMT VSLVVIVFEL 600
  601 TGGLEYIVPL MAAVMTSKWV GDAFGREGIY EAHIRLNGYP FLDAKEEFTH TTLAADVMRP 660
  661 RRSDPPLAVL TQDNMTVDDI ENMINETSYN GFPVIMSKES QRLVGFALRR DLTIAIESAR 720
  721 KKQEGVVGSS RVCFAQHTPS LPAESPRPLK LRSILDMSPF TVTDHTPMEI VVDIFRKLGL 780
  781 RQCLVTHNGR LLGIITKKDI LRHMAQTANQ DPASIMFN

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: CLCN3_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: