Protein Overview: CTCF_RAT

General Information:
Name(s) found:	CTCF_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|5670340\|gb\|AAD27869.2\|AF133731_1 11-zinc finger protein [Rattus norvegicus] [NCBI NR] gi\|30172732\|sp\|Q9R1D1.1\|CTCF_RAT RecName: Full=Transcriptional repressor CTCF; AltName: Full=CCCTC-binding factor; AltName: Full=CTCFL paralog; AltName: Full=11-zinc finger protein [NCBI NR] gi\|25742638\|ref\|NP_114012.1\| CCCTC-binding factor (zinc finger protein) [Rattus norvegicus] [NCBI NR] Transcriptional repressor CTCF OS=Rattus norvegicus GN=Ctcf PE=2 SV=1 [Swiss-Prot] Ensembl_locations(Chr-bp):19-33209849 Transcriptional repressor CTCF [hmr_yeast5_DM3-1_pombe.fasta] CCCTC-binding factor (zinc finger protein) [HMR_022704-rand.fasta] CCCTC-binding factor (zinc finger protein) [Rattus norvegicus]gi\|5670340\|gb\|AAD27869.2\| 11-zinc finger protein [Rattus norvegicus]gi\|30172732\|sp\|Q9R1D1\|CTCF_RAT Transcriptional repressor CTCF (CCCTC-binding factor) (CTCFL paralog) (11-zinc finger protei [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Transcriptional repressor CTCF [EBI-IPI_rat_3.08_07-12-2005_origrev_con.fasta] Transcriptional repressor CTCF (CCCTC-binding factor) (CTCFL paralog) (11-zinc finger protein) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] CCCTC-binding factor [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] 11-zinc finger protein [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 TRANSCRIPTIONAL REPRESSOR CTCF [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] CCCTC-binding factor (zinc finger protein) [Rattus norvegicus] [NCBI-RefSeq_human-rat_na_04-07-2009_con_reversed.fasta] Transcriptional repressor CTCF OS=Rattus norvegicus GN=Ctcf [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	737 amino acids
Gene Ontology:
Cellular Component:	condensed chromosome [UNKNOWN][IEA] nucleus [UNKNOWN][IEA] chromosome, centromeric region [UNKNOWN][IEA] nucleolus [UNKNOWN][IEA] intracellular [IEA] nucleoplasm [UNKNOWN][IEA]
Biological Process:	chromatin modification [IEA] regulation of histone methylation [IEA] regulation of histone acetylation [IEA] regulation of transcription, DNA-dependent [UNKNOWN] chromosome segregation [IEA] regulation of transcription [IEA] regulation of gene expression, epigenetic [UNKNOWN] negative regulation of gene expression [IEA] regulation of gene expression by genetic imprinting [UNKNOWN][IEA] DNA methylation [UNKNOWN] negative regulation of transcription, DNA-dependent [UNKNOWN][IEA] positive regulation of transcription, DNA-dependent [UNKNOWN][IEA] positive regulation of gene expression [UNKNOWN][IEA] regulation of molecular function, epigenetic [UNKNOWN][IEA] nucleosome positioning [UNKNOWN][IEA] maintenance of DNA methylation [UNKNOWN][IEA]
Molecular Function:	DNA binding [UNKNOWN][TAS] transcription factor activity [UNKNOWN][TAS] zinc ion binding [IEA] protein binding [UNKNOWN][IEA] metal ion binding [IEA] chromatin insulator sequence binding [UNKNOWN][IEA] sequence-specific DNA binding [UNKNOWN] promoter binding [UNKNOWN][IEA] transcription activator activity [UNKNOWN][IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEGEAVEAIV EESETFIKGK ERKTYQRRRE GGQEEDACHL PQNQTDGGEV VQDVNSSVQM  60
   61 VMMEQLDPTL LQMKTEVMEG TVAPEAEAAV DDTQIITLQV VNMEEQPINI GELQLVQVPV 120
  121 PVTVPVATTS VEELQGAYEN EVSKEGLAES EPMICHTLPL PEGFQVVKVG ANGEVETLEQ 180
  181 GELPPQEDPS WQKDPDYQPP AKKTKKTKKS KLRYTEEGKD VDVSVYDFEE EQQEGLLSEV 240
  241 NAEKVVGNMK PPKPTKIKKK GVKKTFQCEL CSYTCPRRSN LDRHMKSHTD ERPHKCHLCG 300
  301 RAFRTVTLLR NHLNTHTGTR PHKCPDCDMA FVTSGELVRH RRYKHTHEKP FKCSMCDYAS 360
  361 VEVSKLKRHI RSHTGERPFQ CSLCSYASRD TYKLKRHMRT HSGEKPYECY ICHARFTQSG 420
  421 TMKMHILQKH TENVAKFHCP HCDTVIARKS DLGVHLRKQH SYIEQGKKCR YCDAVFHERY 480
  481 ALIQHQKSHK NEKRFKCDQC DYACRQERHM IMHKRTHTGE KPYACSHCDK TFRQKQLLDM 540
  541 HFKRYHDPNF VPAAFVCSKC GKTFTRRNTM ARHADNCAGP DGVEGENGGE TKKSKRGRKR 600
  601 KMRSKKEDSS DSENAEPDLD DNEEEEEPAV EIEPEPEPQP QPQPQPQPQP VAPAPPPAKK 660
  661 RRGRPPGRTN QPKQNQPTAI IQVEDQNTGA IENIIVEVKK EPDAEPAEGE EEEAQAAPAD 720
  721 APNGDLTPEM ILSMMDR

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Protein Overview: CTCF_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: