Protein Overview: PDE11_RAT

General Information:
Name(s) found:	PDE11_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|81871503\|sp\|Q8VID6.1\|PDE11_RAT RecName: Full=Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A; AltName: Full=cAMP and cGMP phosphodiesterase 11A [NCBI NR] gi\|18266694\|ref\|NP_543169.1\| phosphodiesterase 11A isoform 4 [Rattus norvegicus] [NCBI NR] gi\|18143353\|dbj\|BAB79629.1\| phosphodiesterase 11A4 [Rattus norvegicus] [NCBI NR] Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A OS=Rattus norvegicus GN=Pde11a PE=1 SV=1 [Swiss-Prot] Ensembl_locations(Chr-bp):3-52878425 phosphodiesterase 11A [hmr_yeast5_DM3-1_pombe.fasta] phosphodiesterase 11A [HMR_022704-rand.fasta] phosphodiesterase 11A [Rattus norvegicus]gi\|18143353\|dbj\|BAB79629.1\| phosphodiesterase 11A4 [Rattus norvegicus] [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Phosphodiesterase 11A4 [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] (NM_080893) phosphodiesterase 11A [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A (cAMP and cGMP phosphodiesterase 11A) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] phosphodiesterase 11A isoform 4 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] phosphodiesterase 11A4 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] phosphodiesterase 11A [Rattus norvegicus] [nr-271106-contam.fasta] Tax_Id=10116 Gene_Symbol=Pde11a Isoform 1 of Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A [rat-ipi-250309-contam.fasta] Isoform 1 of Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A OS=Rattus norvegicus GN=Pde11a [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	935 amino acids
Gene Ontology:
Cellular Component:	soluble fraction [IDA] cytoplasm [IEA] cytosol [IEA] perikaryon [IDA]
Biological Process:	signal transduction [IEA] cGMP catabolic process [IDA] cAMP catabolic process [IDA]
Molecular Function:	catalytic activity [IEA] metal ion binding [IEA] cAMP binding [IDA] 3',5'-cyclic-GMP phosphodiesterase activity [IEA] cyclic-nucleotide phosphodiesterase activity [IDA] cGMP binding [IDA] 3',5'-cyclic-nucleotide phosphodiesterase activity [IEA] hydrolase activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAASRLDFGE VETFLDRHPE LFEDYLMRKG KQELVDKWLQ RHSSGQGASD LRPALAGASS  60
   61 LAQSSARGST GIGGGAGPQG SANSHPASGG GESAGVPLSP SWASGSRGDG NLQRRASQKE 120
  121 LRKSFARSKA IHVNRTYDEQ VTSRAQEPLS SVRRRALLRK ASSLPPTTAH ILSALLESRV 180
  181 NLPQYPPTAI DYKCHLKKHN ERQFFLELVK DISNDLDLTS LSYKILIFVC LMVDADRCSL 240
  241 FLVEGAAAGK KTLVSKFFDV HAGTPLLPCS TTENSNEVQV PWGKGIIGYV GEHGETVNIP 300
  301 DAYQDRRFND EIDKLTGYKT KSLLCMPIRN SDGEIIGVAQ AINKVPEGAP FTEDDEKVMQ 360
  361 MYLPFCGIAI SNAQLFAASR KEYERSRALL EVVNDLFEEQ TDLEKIVKKI MHRAQTLLKC 420
  421 ERCSVLLLED IESPVVKFTK SFELMSPKCS ADAENSFKES VEKSSYSDWL INNSIAELVA 480
  481 STGLPVNVSD AYQDPRFDAE ADQISGFHIR SVLCVPIWNS NHQIIGVAQV LNRLDGKPFD 540
  541 DADQRLFEAF VIFCGLGINN TIMYDQVKKS WAKQSVALDV LSYHATCSKA EVDKFKAANI 600
  601 PLVSELAIDD IHFDDFSLDV DAMITAALRM FMELGMVQKF KIDYETLCRW LLTVRKNYRM 660
  661 VLYHNWRHAF NVCQLMFAML TTAGFQEILT EVEILAVIVG CLCHDLDHRG TNNAFQAKSD 720
  721 SALAQLYGTS ATLEHHHFNH AVMILQSEGH NIFANLSSKE YSDLMQLLKQ SILATDLTLY 780
  781 FERRTEFFEL VSKGAYDWSI TSHRDVFRSM LMTACDLGAV TKPWEISRQV AELVTSEFFE 840
  841 QGDRERSELK LTPSAIFDRN RKDELPRLQL EWIDSICMPL YQALVKVNAK LKPMLDSVAA 900
  901 NRRKWEELHQ KRLQVSAASP VPSSPSPAVA GEDRL

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.95

Protein Overview: PDE11_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: