Protein Overview: JAK3_RAT

General Information:
Name(s) found:	JAK3_RAT [Swiss-Prot]
Description(s) found: Found 16 descriptions. SHOW ALL	Tyrosine-protein kinase JAK3 OS=Rattus norvegicus GN=Jak3 PE=2 SV=1 [Swiss-Prot]
Organism:	Rattus norvegicus
Length:	1100 amino acids
Gene Ontology:
Cellular Component:	cytoskeleton [IEA] cytoplasm [IDA] membrane [IEA] endomembrane system [IEA]
Biological Process:	peptidyl-tyrosine phosphorylation [UNKNOWN][IEA] tyrosine phosphorylation of Stat5 protein [IMP] cytokine-mediated signaling pathway [UNKNOWN][IDA] positive regulation of calcium ion transport [IMP] protein amino acid autophosphorylation [IMP] intracellular protein kinase cascade [UNKNOWN][IEA] enzyme linked receptor protein signaling pathway [UNKNOWN] positive regulation of transcription from RNA polymerase II promoter [UNKNOWN] positive regulation of activated T cell proliferation [IMP] positive regulation of immune response [IMP] elevation of cytosolic calcium ion concentration [IMP]
Molecular Function:	nucleotide binding [IEA] ATP binding [IEA] protein tyrosine kinase activity [UNKNOWN][IMP] protein binding [UNKNOWN][IEA] non-membrane spanning protein tyrosine kinase activity [IEA] Janus kinase activity [UNKNOWN][IEA] transcription factor binding [IC] transferase activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAPPSEETPL ISQRSCSLSS SEAGALHVLL PPRGPGPPQR LSFSFGDYLA EDLCVRAAKA  60
   61 CGILPVYHSL FALATEDLSC WFPPSHIFSI EDVDTQVLVY RLRFYFPGWF GLETCHRFGL 120
  121 HKDLTSAILD VHVLEHLFAQ HRSDLVSGRL PVGLSLKDQG EFLSLAVLDL AQMARKQAQR 180
  181 PGELLKSVSY KACLPPSLRD LIQGQSFVTR RRIRRTVVQA LAPCSSLPSR PYALMAKYIL 240
  241 DLERLHPAAT TESFLVGLPG AQEEPGCLRV TGDNGIAWSS KDQELFQTFC DFPEIVDVSI 300
  301 KQAPRVGPAG EHRLVTITRM DGHILEAEFP GLPEALSFVA LVDGYFRLIC DSRHFFCKEV 360
  361 APPRLLEEEA ELCHGPITLD FAIHKLKAAG SLPGSYILRR SPQDYDSFLL TACVQTPLGP 420
  421 DYKGCLIRQD PSGAFSLVGL SQLHRSLQEL LTACWHSGLQ VDGTALNLTS CCVPRPKEKS 480
  481 NLIVVRRGRN PTPAPGHSPS CCALTKLSFH TIPADSLEWH ENLGHGSFTK IFHGHRREVV 540
  541 DGETHDTEVL LKVMDSRHQN CMESFLEAAS LMSQVSYPHL VLLHGVCMAG DSIMVQEFVY 600
  601 LGAIDTYLRK RGHLVPASWK LQVTKQLAYA LNYLEDKGLP HGNVSARKVL LAREGVDGNP 660
  661 PFIKLSDPGV SPTVLSLEML TDRIPWVAPE CLQEAGTLNL EADKWGFGAT TWEVFSGAPM 720
  721 HITSLEPAKK LKFYEDRGQL PALKWTELEG LIAQCMAYDP GRRPSFRAIL RDLNGLITSD 780
  781 YELLSDPTPG IPNPRDELCG GAQLYACQDP AIFEERHLKY ISLLGKGNFG SVELCRYDPL 840
  841 GDNTGPLVAV KQLQHSGPEQ QRDFQREIQI LKALHCDFIV KYRGVSYGPG RQELRLVMEY 900
  901 LPSGCLRDFL QRHRARLHND RLLLFAWQIC KGMEYLGARR CVHRDLAARN ILVESEAHVK 960
  961 IADFGLAKLL PLGKDYYVVR VPGQSPIFWY APESLSDNIF SRQSDVWSFG VVLYELFTYS1020
 1021 DKSCSPSTEF LRMIGPEREG SPLCHLLELL AEGRRLPPPS TCPTEVQELM QLCWSPNPQD1080
 1081 RPAFDTLSPQ LDALWRGSPG

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.95

Protein Overview: JAK3_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: