Protein Overview: HMOX1_RAT

General Information:
Name(s) found:	HMOX1_RAT [Swiss-Prot]
Description(s) found: Found 22 descriptions. SHOW ALL	Heme oxygenase 1 OS=Rattus norvegicus GN=Hmox1 PE=1 SV=1 [Swiss-Prot]
Organism:	Rattus norvegicus
Length:	289 amino acids
Gene Ontology:
Cellular Component:	nucleus [IDA] caveola [IDA] microsome [IDA] cytosol [IDA] endoplasmic reticulum [UNKNOWN][IDA] nucleolus [IDA] plasma membrane [TAS]
Biological Process:	iron ion homeostasis [UNKNOWN][IEA] response to estrogen stimulus [IDA] negative regulation of cell proliferation [IDA] positive regulation of I-kappaB kinase/NF-kappaB cascade [UNKNOWN][IEA] phospholipid metabolic process [TAS] positive regulation of anti-apoptosis [IDA] heme oxidation [UNKNOWN][IEA][TAS] negative regulation of mast cell degranulation [IDA] regulation of transcription factor activity [IDA] positive regulation of smooth muscle cell proliferation [UNKNOWN] response to oxidative stress [UNKNOWN][IDA] negative regulation of DNA binding [IDA] response to hypoxia [IEP] cell death [IDA] anti-apoptosis [UNKNOWN] angiogenesis [IDA] negative regulation of smooth muscle cell proliferation [UNKNOWN] negative regulation of mast cell cytokine production [IDA] response to stimulus [UNKNOWN][IEA] erythrocyte homeostasis [UNKNOWN][IEA] regulation of transcription from RNA polymerase II promoter in response to oxidative stress [IDA] small GTPase mediated signal transduction [IDA] cellular response to nutrient [IEP] protein homooligomerization [UNKNOWN][IEA] DNA damage response, signal transduction resulting in induction of apoptosis [IDA] heme catabolic process [UNKNOWN][IDA] negative regulation of transcription factor activity [IDA] response to nicotine [UNKNOWN][IEA] response to hydrogen peroxide [IDA] regulation of blood pressure [IDA] healing during inflammatory response [UNKNOWN][IEA] intracellular signaling pathway [IDA] oxidation reduction [IEA]
Molecular Function:	protein binding [IPI] protein homodimerization activity [UNKNOWN][IEA] oxidoreductase activity [IDA] metal ion binding [IEA] heme oxygenase (decyclizing) activity [UNKNOWN][IDA][IEA][TAS] phospholipase D activity [IDA] signal transducer activity [UNKNOWN][IEA] enzyme binding [IPI] heme binding [UNKNOWN][IDA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MERPQLDSMS QDLSEALKEA TKEVHIRAEN SEFMRNFQKG QVSREGFKLV MASLYHIYTA  60
   61 LEEEIERNKQ NPVYAPLYFP EELHRRAALE QDMAFWYGPH WQEAIPYTPA TQHYVKRLHE 120
  121 VGGTHPELLV AHAYTRYLGD LSGGQVLKKI AQKAMALPSS GEGLAFFTFP SIDNPTKFKQ 180
  181 LYRARMNTLE MTPEVKHRVT EEAKTAFLLN IELFEELQAL LTEEHKDQSP SQTEFLRQRP 240
  241 ASLVQDTTSA ETPRGKSQIS TSSSQTPLLR WVLTLSFLLA TVAVGIYAM

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: HMOX1_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: