Protein Overview: MET_RAT

General Information:
Name(s) found:	MET_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|1771558\|emb\|CAA65582.1\| c-met [Rattus norvegicus] [NCBI NR] gi\|13629392\|sp\|P97523.1\|MET_RAT RecName: Full=Hepatocyte growth factor receptor; Short=HGF receptor; AltName: Full=Scatter factor receptor; Short=SF receptor; AltName: Full=HGF/SF receptor; AltName: Full=Met proto-oncogene tyrosine kinase; AltName: Full=c [NCBI NR] Hepatocyte growth factor receptor OS=Rattus norvegicus GN=Met PE=1 SV=1 [Swiss-Prot] Ensembl_locations(Chr-bp):4-47842296 Hepatocyte growth factor receptor precursor [hmr_yeast5_DM3-1_pombe.fasta] c-met [Rattus norvegicus]gi\|13629392\|sp\|P97523\|MET_RAT Hepatocyte growth factor receptor precursor (Met proto-oncogene tyrosine kinase) (c-met) (HGF receptor) (HGF-SF receptor) [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Hepatocyte growth factor receptor precursor [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] Hepatocyte growth factor receptor precursor (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] c-met [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 HEPATOCYTE GROWTH FACTOR RECEPTOR PRECURSOR [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=10116 Gene_Symbol=Met Hepatocyte growth factor receptor [rat-ipi-250309-contam.fasta] Hepatocyte growth factor receptor OS=Rattus norvegicus GN=Met [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	1382 amino acids
Gene Ontology:
Cellular Component:	postsynaptic density [IDA] excitatory synapse [IDA] neuronal cell body [IDA] neuron projection [IDA] plasma membrane [UNKNOWN][IDA] membrane fraction [UNKNOWN][IEA] dendrite [IDA] extracellular space [IDA] basal plasma membrane [UNKNOWN] cytoplasm [IDA] postsynaptic membrane [IDA] integral to membrane [NAS] flagellum [IDA]
Biological Process:	oligodendrocyte development [IEP] male gonad development [IEP] multicellular organismal development [IEA] response to wounding [IEP] protein amino acid autophosphorylation [UNKNOWN][IDA] lactation [IEP] central nervous system neuron differentiation [IEP] positive regulation of DNA replication [IMP] positive regulation of mitosis [IMP] placenta development [UNKNOWN][IEA] regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling [UNKNOWN][IEA] activation of MAPK activity [UNKNOWN][IEA] neuron migration [IDA][IMP] cellular response to interleukin-6 [IEP] cellular response to glucose stimulus [IEP] liver development [UNKNOWN][IEP] ovarian follicle cell development [IEP] cellular response to peptide hormone stimulus [IEP] positive regulation of neuron projection development [IMP] muscle cell migration [UNKNOWN][IEA] positive regulation of gene-specific transcription from RNA polymerase II promoter [IMP] response to protein stimulus [IEP] positive regulation of dendrite morphogenesis [IMP] negative regulation of gene-specific transcription from RNA polymerase II promoter [IMP] pancreas development [IEP] positive regulation of peptidyl-serine phosphorylation [IMP] brain development [UNKNOWN][IEP] response to organic cyclic substance [IEP] cell aging [IEP] response to peptide hormone stimulus [IEP] response to acid [IEP] muscle organ development [UNKNOWN][IEA] hepatocyte growth factor receptor signaling pathway [UNKNOWN][IEA] cellular response to inorganic substance [IEP] sperm motility [IMP] negative regulation of peptidyl-threonine phosphorylation [IMP] skeletal muscle tissue development [UNKNOWN][IEA] positive regulation of gene expression [IMP] response to drug [IEP] cellular response to growth factor stimulus [IEP] myoblast proliferation [UNKNOWN][IEA] cellular response to arsenic [IEP] myotube differentiation [UNKNOWN][IEA] positive regulation of peptidyl-threonine phosphorylation [IMP] adult behavior [UNKNOWN][IEA]
Molecular Function:	nucleotide binding [IEA] hepatocyte growth factor receptor activity [UNKNOWN][IMP] ATP binding [IEA] phosphoinositide 3-kinase binding [IDA] protein tyrosine kinase activity [IDA] protein binding [UNKNOWN][IDA] protein heterodimerization activity [IDA] phospholipase binding [IPI] protein kinase activity [UNKNOWN] beta-catenin binding [IPI] receptor activity [IEA] transferase activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
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    1 MKAPTALAPG ILLLLLTLAQ RSHGECKEAL VKSEMNVNMK YQLPNFTAET PIHNVVLPGH  60
   61 HIYLGATNYI YVLNDKDLQK VSEFKTGPVV EHPDCFPCQD CSSKANVSGG VWKDNVNMAL 120
  121 LVDTYYDDQL ISCGSVNRGT CQRHVLPPDN AADIQSEVHC MFSPLAEEES GQCPDCVVSA 180
  181 LGAKVLLSEK DRFINFFVGN TINSSYPPDY SLHSISVRRL KETQDGFKFL TDQSYIDVLP 240
  241 EFRDSYPIKY IHAFESNHFI YFLTVQKETL DAQTFHTRII RFCSVDSGLH SYMEMPLECI 300
  301 LTEKRRKRST REEVFNILQA AYVSKPGANL AKQIGASPYD DILYGVFAQS KPDSAEPMNR 360
  361 SAVCAFPIKY VNDFFNKIVN KNNVRCLQHF YGPNHEHCFN RTLLRNSSGC EVRSDEYRTE 420
  421 FTTALQRVDL FMGRLNHVLL TSISTFIKGD LTIANLGTSE GRFMQVVLSR TAHFTPHVNF 480
  481 LLDSYPVSPE VIVEHPSNQN GYTLVVTGKK ITKIPLNGLG CGHFQSCSQC LSPPYFIQCG 540
  541 WCHNRCVHSN ECPSGTWTQE ICLPAVYKVF PTSAPLEGGT MLTICGWDFG FKKNNKFDLR 600
  601 KTKVLLGNES CTLTLSESTT NTLKCTVGPA MSEHFNVSVI VSNSRETTQY SAFSYVDPVI 660
  661 TSISPRYGPH AGGTLLTLTG KYLNSGNSRH ISIGGKTCTL KSVSDSILEC YTPGHTVSAE 720
  721 FPVKLKIDLA DRVTSSFSYR EDPVVSEIHP TKSFISGGST ITGIGKNLNS VSTPKLVIEV 780
  781 HDVGVNYTVA CQHRSSSEII CCTTPSLRQL DLQLPLKTKA FFLLDGILSK HFDLTYVHDP 840
  841 MFKPFEKPVM ISMGNENVVE IKGDDIDPEA VKGEVLKVGN KSCENLHWHS EALLCTVPSD 900
  901 LLKLNGGELN IEWKQAVSST VLGKVIVQPD QNFAGLIIGA VSISVVVLLV SGLFLWLRKR 960
  961 KHKDLGSELV RYDARVHTPH LDRLVSARSV SPTTEMVSNE SVDYRATFPE DQFPNSSQNG1020
 1021 ACRQVQYLLT DLSPILTSGD SDISSPLLQN TVHIDLSALN PELVQAVPHV VIGPSSLIVH1080
 1081 FNEVIGRGHF GCVYHGTLLD SDGKKIHCAV KSLNRITDIE EVSQFLTEGI IMKDFSHPNV1140
 1141 LSLLGICLRS EGSPLVVLPY MKHGDLRNFI RNETHNPTVK DLIGFGLQVA KGMKYLVSKK1200
 1201 FVHRDLAARN CMLDEKFTVK VADFGLARDM YDKEYYSVHN KTGAKLPVKW MALESLQTQK1260
 1261 FTTKSDVWSF GVLLWELMTR GAPPYPDVNT FDITIYLLQG RRLLQPEYCP DALYEVMLKC1320
 1321 WHPKAEMRPS VSELVSRISS IFSTFIGEHY VHVNATYVNV KCVAPYPSLL PSQDNIDGEA1380
 1381 NT

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: MET_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: