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Protein Overview: C11B2_RAT

General Information:
Name(s) found: C11B2_RAT [Swiss-Prot]
Description(s) found:
Found 16 descriptions.
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  • Cytochrome P450 11B2, mitochondrial OS=Rattus norvegicus GN=Cyp11b2 PE=1 SV=1 [Swiss-Prot]
    • Organism: Rattus norvegicus
    Length: 510 amino acids

    Gene Ontology:
    Cellular Component: dendrite [IDA]
    mitochondrial membrane [IEA]
    mitochondrion [UNKNOWN][IEA]
    membrane [IEA]
    Biological Process: drinking behavior [UNKNOWN][IEA]
    response to salt stress [IEP]
    [NOT]cortisol biosynthetic process [UNKNOWN]
    potassium ion homeostasis [UNKNOWN]
    sodium ion homeostasis [UNKNOWN]
    steroid biosynthetic process [UNKNOWN]
    C21-steroid hormone biosynthetic process [UNKNOWN][IDA]
    response to peptide hormone stimulus [IEP]
    regulation of systemic arterial blood pressure by circulatory renin-angiotensin [UNKNOWN][IEA]
    positive regulation of blood pressure [IMP]
    regulation of blood volume by renal aldosterone [UNKNOWN][IEA]
    response to insulin stimulus [IEP]
    response to drug [IEP]
    aldosterone biosynthetic process [UNKNOWN][IEA]
    ion homeostasis [UNKNOWN][IEA]
    oxidation reduction [IEA]
    Molecular Function: metal ion binding [IEA]
    electron carrier activity [IEA]
    corticosterone 18-monooxygenase activity [IDA]
    steroid 11-beta-monooxygenase activity [UNKNOWN][IDA]
    monooxygenase activity [IEA]
    heme binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGACDNDFIE LHSRVTADVW LARPWQCLHR TRALGTTATL APKTLKPFEA IPQYSRNKWL  60
   61 KMIQILREQG QENLHLEMHQ AFQELGPIFR HSAGGAQIVS VMLPEDAEKL HQVESILPRR 120
  121 MHLEPWVAHR ELRGLRRGVF LLNGAEWRFN RLKLNPNVLS PKAVQNFVPM VDEVARDFLE 180
  181 ALKKKVRQNA RGSLTMDVQQ SLFNYTIEAS NFALFGERLG LLGHDLNPGS LKFIHALHSM 240
  241 FKSTTQLLFL PRSLTRWTST QVWKEHFDAW DVISEYANRC IWKVHQELRL GSSQTYSGIV 300
  301 AALITQGALP LDAIKANSME LTAGSVDTTA IPLVMTLFEL ARNPDVQQAL RQETLAAEAS 360
  361 IAANPQKAMS DLPLLRAALK ETLRLYPVGG FLERILNSDL VLQNYHVPAG TLVLLYLYSM 420
  421 GRNPAVFPRP ERYMPQRWLE RKRSFQHLAF GFGVRQCLGR RLAEVEMLLL LHHMLKTFQV 480
  481 ETLRQEDVQM AYRFVLMPSS SPVLTFRPIS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.86

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle