Protein Overview: DVL1_RAT

General Information:
Name(s) found:	DVL1_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|5649174\|gb\|AAD33897.2\|AF143546_1 dishevelled-1 [Rattus norvegicus] [NCBI NR] gi\|5649172\|gb\|AAD33896.2\|AF143545_1 dishevelled-1 [Rattus norvegicus] [NCBI NR] gi\|20141291\|sp\|Q9WVB9.3\|DVL1_RAT RecName: Full=Segment polarity protein dishevelled homolog DVL-1; Short=Dishevelled-1; AltName: Full=DSH homolog 1 [NCBI NR] gi\|149024839\|gb\|EDL81336.1\| dishevelled, dsh homolog 1 (Drosophila) [Rattus norvegicus] [NCBI NR] gi\|13929170\|ref\|NP_114008.1\| dishevelled, dsh homolog 1 [Rattus norvegicus] [NCBI NR] Segment polarity protein dishevelled homolog DVL-1 OS=Rattus norvegicus GN=Dvl1 PE=1 SV=3 [Swiss-Prot] Ensembl_locations(Chr-bp):5-193026231 Segment polarity protein dishevelled homolog DVL-1 [hmr_yeast5_DM3-1_pombe.fasta] dishevelled 1 [HMR_022704-rand.fasta] dishevelled, dsh homolog 1 [Rattus norvegicus]gi\|20141291\|sp\|Q9WVB9\|DVL1_RAT Segment polarity protein dishevelled homolog DVL-1 (Dishevelled-1) (DSH homolog 1)gi\|5649174\|gb\|AAD33897.2\| dishevelled-1 [Rattus norvegicus]gi\|5649172\|gb\|AAD33896.2\| dishevel [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Segment polarity protein dishevelled homolog DVL-1 [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] (NM_031820) dishevelled 1 [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] Segment polarity protein dishevelled homolog DVL-1 (Dishevelled-1) (DSH homolog 1) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] dishevelled, dsh homolog 1 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] dishevelled, dsh homolog 1 (Drosophila) [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] dishevelled-1 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 SEGMENT POLARITY PROTEIN DISHEVELLED HOMOLOG DVL-1 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=10116 Gene_Symbol=Dvl1 Segment polarity protein dishevelled homolog DVL-1 [rat-ipi-250309-contam.fasta] segment polarity protein dishevelled homolog DVL-1 [Rattus norvegicus] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta] Segment polarity protein dishevelled homolog DVL-1 OS=Rattus norvegicus GN=Dvl1 [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	695 amino acids
Gene Ontology:
Cellular Component:	growth cone [IDA] dendrite [IDA] microtubule cytoskeleton [IDA] synaptosome [UNKNOWN][IEA] cytoplasm [IEA] cytoplasmic vesicle [UNKNOWN] cytoplasmic membrane-bounded vesicle [UNKNOWN][IEA] neuronal cell body [IDA] synapse [UNKNOWN][IEA] intracellular [IEA] axon [IDA] microtubule [IDA]
Biological Process:	neural tube development [UNKNOWN][IEA] multicellular organismal development [IEA] synapse organization [UNKNOWN] transcription from RNA polymerase II promoter [UNKNOWN] receptor clustering [UNKNOWN][IEA] negative regulation of protein kinase activity [UNKNOWN][IEA] neurotransmitter secretion [UNKNOWN][IEA] dendrite morphogenesis [UNKNOWN][IEA] neuromuscular junction development [UNKNOWN][IEA] regulation of neurotransmitter levels [UNKNOWN] Wnt receptor signaling pathway [TAS] Wnt receptor signaling pathway through beta-catenin [UNKNOWN][IEA] positive regulation of Wnt receptor signaling pathway [UNKNOWN][IEA] protein localization in nucleus [UNKNOWN][IEA]
Molecular Function:	protein kinase binding [IPI] identical protein binding [UNKNOWN][IEA] protein binding [UNKNOWN] Rac GTPase binding [IPI] signal transducer activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAETKIIYHM DEEETPYLVK LPVAPERVTL ADFKNVLSNR PVHAYKFFFK SMDQDFGVVK  60
   61 EEIFDDNAKL PCFNGRVVSW LVLAEGAHSD AGSQGTDSHT DLPPPLERTG GIGDSRPPSF 120
  121 HPNVASSRDG MDNETGTESM VSHRRERARR RNRDEAARTN GHPRGDRRRE LGLPPDSAST 180
  181 VLSSELESSS FIDSDEEDNT SRLSSSTEQS TSSRLIRKHK CRRRKQRLRQ TDRASSFSSI 240
  241 TDSTMSLNII TVTLNMERHH FLGISIVGQS NDRGDGGIYI GSIMKGGAVA ADGRIEPGDM 300
  301 LLQVNDVNFE NMSNDDAVRV LREIVSQTGP ISLTVAKCWD PTPRSYFTIP RADPVRPIDP 360
  361 AAWLSHTAAL TGALPRYGTS PCSSAITRTS SSSLTSSVPG APQLEEAPLT VKSDMSAIVR 420
  421 VMQLPDSGLE IRDRMWLKIT IANAVIGADV VDWLYTHVEG FKERREARKY ASSMLKHGFL 480
  481 RHTVNKITFS EQCYYVFGDL CSNLASLNLN SGSSGASDQD TLAPLPHPSV PWPLGQGYPY 540
  541 QYPGPPPCFP PAYQDPGFSY GSGSAGSQQS EGSKSSGSTR SSHRTPGREE RRATGAGGSG 600
  601 SESDHTVPSG SGSTGWWERP VSQLSRGSSP RSQASAVAPG LPPLHPLTKA YAVVGGPPGG 660
  661 PPVRELAAVP PELTGSRQSF QKAMGNPCEF FVDIM

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.97

Protein Overview: DVL1_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: