Protein Overview: PGFRA_RAT

General Information:
Name(s) found:	PGFRA_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	pir\|\|PFRTGA platelet-derived growth factor receptor alpha precursor - rat [NCBI NR] gi\|129894\|sp\|P20786.2\|PGFRA_RAT RecName: Full=Alpha-type platelet-derived growth factor receptor; AltName: Full=PDGF-R-alpha; AltName: Full=CD140 antigen-like family member A; AltName: CD_antigen=CD140a; Flags: Precursor [NCBI NR] Platelet-derived growth factor receptor alpha OS=Rattus norvegicus GN=Pdgfra PE=1 SV=2 [Swiss-Prot] (P20786) Alpha platelet-derived growth factor receptor precursor (EC 2.7.1.112) (PDGF-R-alpha) [Swiss-Prot] Ensembl_locations(Chr-bp):14-33994305 Alpha platelet-derived growth factor receptor precursor [hmr_yeast5_DM3-1_pombe.fasta] Alpha platelet-derived growth factor receptor precursor (PDGF-R-alpha)gi\|66815\|pir\|\|PFRTGA platelet-derived growth factor receptor alpha precursor - rat [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Alpha platelet-derived growth factor receptor precursor [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] Alpha-type platelet-derived growth factor receptor precursor (PDGF-R-alpha) (CD140 antigen-like family member A) (CD140a antigen) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 ALPHA PLATELET-DERIVED GROWTH FACTOR RECEPTOR PRECURSOR [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Alpha platelet-derived growth factor receptor precursor (PDGF-R-alpha) (CD140a antigen) [nr-271106-contam.fasta] Tax_Id=10116 Gene_Symbol=Pdgfra Alpha-type platelet-derived growth factor receptor [rat-ipi-250309-contam.fasta] Alpha-type platelet-derived growth factor receptor OS=Rattus norvegicus GN=Pdgfra [011711_HMR.fasta] Alpha-type platelet-derived growth factor receptor OS=Rattus norvegicus GN=Pdgfra PE=1 SV=2 [UNIPROT_RAT_07-21-2011_reversed.fasta]
Organism:	Rattus norvegicus
Length:	1088 amino acids
Gene Ontology:
Cellular Component:	integral to plasma membrane [UNKNOWN][IEA] membrane [IEA] cellular_component [ND] plasma membrane [UNKNOWN]
Biological Process:	response to cytokine stimulus [IEP] response to hyperoxia [IEP] peptidyl-tyrosine phosphorylation [UNKNOWN][IEA] response to estrogen stimulus [IEP] inner ear development [IEP] positive regulation of cell proliferation [UNKNOWN][IMP] palate development [UNKNOWN][IEA] protein amino acid autophosphorylation [UNKNOWN][IEA] anatomical structure morphogenesis [UNKNOWN] odontogenesis of dentine-containing tooth [UNKNOWN][IEA] positive regulation of DNA replication [UNKNOWN][IEA] female gonad development [UNKNOWN] face morphogenesis [UNKNOWN][IEA] wound healing [IEP] in utero embryonic development [UNKNOWN][IEA] gliogenesis [IEP][NAS] positive regulation of fibroblast proliferation [UNKNOWN][IEA] response to inorganic substance [IEP] adrenal gland development [UNKNOWN] lung development [UNKNOWN][IEA] response to organic substance [IEP] estrogen metabolic process [UNKNOWN] platelet-derived growth factor receptor signaling pathway [UNKNOWN][IEA] response to hormone stimulus [IEP] skeletal system morphogenesis [UNKNOWN][IEA] organ morphogenesis [UNKNOWN] luteinization [UNKNOWN] vascular endothelial growth factor receptor signaling pathway [IEA] male genitalia development [UNKNOWN][IEA] extracellular matrix organization [UNKNOWN][IEA] response to estradiol stimulus [IEP] Leydig cell differentiation [UNKNOWN] positive regulation of cell migration [UNKNOWN][IEA]
Molecular Function:	growth factor binding [UNKNOWN] protein homodimerization activity [UNKNOWN][IEA] platelet-derived growth factor receptor binding [UNKNOWN][IEA] vascular endothelial growth factor receptor activity [UNKNOWN][IEA] protein dimerization activity [NAS] receptor activity [IEA] platelet-derived growth factor binding [UNKNOWN][IEA] nucleotide binding [IEA] platelet-derived growth factor alpha-receptor activity [UNKNOWN][IDA][TAS] ATP binding [IEA] protein tyrosine kinase activity [UNKNOWN] protein heterodimerization activity [IEA] transferase activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGTSQAFLVL SCLLTGPSLI VCQLLLPSIL PNENEKIVPL SSSFSLRCFG ESEVSWQHPM  60
   61 SEEEDPNVEI RTEENNSSLF VTVLEVVNAS AAHTGWYTCY YNHTQTEESE IEGRHIYIYV 120
  121 PDPDMAFVPL GMTDSLVIVE EDDSAIIPCL TTDPDTEVTL HNNGRLVPAS YDSRQGFNGT 180
  181 FSVGPYICEA TVRGRTFKTS EFNVYALKAT SELNLEMDTR QTVYKAGETI VVTCAVFNNE 240
  241 VVDLQWTYPG EVRNKGITML EEIKLPSIKL VYTLTVPKAT VKDSGDYECA ARQATKEVKE 300
  301 MKTVTISVHE KGFVQIRPTF GHLETVNLHQ VREFVVEVQA YPTPRISWLK DNLTLIENLT 360
  361 EITTDVQRSQ ETRYQSKLKL IRAKEEDSGH YTIIVQNDDD MKSYTFELST LVPASILELV 420
  421 DDHHGSGGGQ TVRCTAEGTP LPNIEWMICK DIKKCNNDTS WTVLASNVSN IITEFHQRGR 480
  481 STVEGRVSFA KVEETIAVRC LAKNDLGIGN RELKLVAPSL RSELTVAAAV LVLLVIVIVS 540
  541 LIVLVVIWKQ KPRYEIRWRV IESISPDGHE YIYVDPMQLP YDSRWEFPRD GLVLGRILGS 600
  601 GAFGKVVEGT AYGLSRSQPV MKVAVKMLKP TARSSEKQAL MSELKIMTHL GPHLNIVNLL 660
  661 GACTKSGPIY IITEYCFYGD LVNYLHKNRD SFMSRHPEKP KKDLDIFGLN PADESTRSYV 720
  721 ILSFENNGDY VDMKQADTTQ YVPMLERKEV SKYSDIQRSL YDRPASYKKK SMLDSEAKNL 780
  781 LSDDDSEGLT LLDLLSFTYQ VARGMEFLAS KNCVHRDLAA RNVLLAQGKI VKICDFGLAR 840
  841 DIMHDSNYVS KGSTFLPVKW MAPESIFDNL YTTLSDVWSY GVLLWEIFSL GGTPYPGMMV 900
  901 DSTFYNKIKS GYRMAKPDHA TSEVYEIMVQ CWNSEPEKRP SFYHLSEIVE NLLPGQYKKS 960
  961 YEKIHLDFLK SDHPAVARMR VDSDNAYIGV TYKNEEDKLK EWEGGLDEQR LSADSGYIIP1020
 1021 LPDIDPVPEE EDLGKRNRHS SQTSEESAIE TGSSSSTFIK REDETIEDID MMDDIGIDSS1080
 1081 DLVEDSFL

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: PGFRA_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: