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Protein Overview: PGFRA_RAT

General Information:
Name(s) found: PGFRA_RAT [Swiss-Prot]
Description(s) found:
Found 13 descriptions.
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  • Platelet-derived growth factor receptor alpha OS=Rattus norvegicus GN=Pdgfra PE=1 SV=2 [Swiss-Prot]
    • Organism: Rattus norvegicus
    Length: 1088 amino acids

    Gene Ontology:
    Cellular Component: integral to plasma membrane [UNKNOWN][IEA]
    membrane [IEA]
    cellular_component [ND]
    plasma membrane [UNKNOWN]
    Biological Process: response to cytokine stimulus [IEP]
    response to hyperoxia [IEP]
    peptidyl-tyrosine phosphorylation [UNKNOWN][IEA]
    response to estrogen stimulus [IEP]
    inner ear development [IEP]
    positive regulation of cell proliferation [UNKNOWN][IMP]
    palate development [UNKNOWN][IEA]
    protein amino acid autophosphorylation [UNKNOWN][IEA]
    anatomical structure morphogenesis [UNKNOWN]
    odontogenesis of dentine-containing tooth [UNKNOWN][IEA]
    positive regulation of DNA replication [UNKNOWN][IEA]
    female gonad development [UNKNOWN]
    face morphogenesis [UNKNOWN][IEA]
    wound healing [IEP]
    in utero embryonic development [UNKNOWN][IEA]
    gliogenesis [IEP][NAS]
    positive regulation of fibroblast proliferation [UNKNOWN][IEA]
    response to inorganic substance [IEP]
    adrenal gland development [UNKNOWN]
    lung development [UNKNOWN][IEA]
    response to organic substance [IEP]
    estrogen metabolic process [UNKNOWN]
    platelet-derived growth factor receptor signaling pathway [UNKNOWN][IEA]
    response to hormone stimulus [IEP]
    skeletal system morphogenesis [UNKNOWN][IEA]
    organ morphogenesis [UNKNOWN]
    luteinization [UNKNOWN]
    vascular endothelial growth factor receptor signaling pathway [IEA]
    male genitalia development [UNKNOWN][IEA]
    extracellular matrix organization [UNKNOWN][IEA]
    response to estradiol stimulus [IEP]
    Leydig cell differentiation [UNKNOWN]
    positive regulation of cell migration [UNKNOWN][IEA]
    Molecular Function: growth factor binding [UNKNOWN]
    protein homodimerization activity [UNKNOWN][IEA]
    platelet-derived growth factor receptor binding [UNKNOWN][IEA]
    vascular endothelial growth factor receptor activity [UNKNOWN][IEA]
    protein dimerization activity [NAS]
    receptor activity [IEA]
    platelet-derived growth factor binding [UNKNOWN][IEA]
    nucleotide binding [IEA]
    platelet-derived growth factor alpha-receptor activity [UNKNOWN][IDA][TAS]
    ATP binding [IEA]
    protein tyrosine kinase activity [UNKNOWN]
    protein heterodimerization activity [IEA]
    transferase activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGTSQAFLVL SCLLTGPSLI VCQLLLPSIL PNENEKIVPL SSSFSLRCFG ESEVSWQHPM  60
   61 SEEEDPNVEI RTEENNSSLF VTVLEVVNAS AAHTGWYTCY YNHTQTEESE IEGRHIYIYV 120
  121 PDPDMAFVPL GMTDSLVIVE EDDSAIIPCL TTDPDTEVTL HNNGRLVPAS YDSRQGFNGT 180
  181 FSVGPYICEA TVRGRTFKTS EFNVYALKAT SELNLEMDTR QTVYKAGETI VVTCAVFNNE 240
  241 VVDLQWTYPG EVRNKGITML EEIKLPSIKL VYTLTVPKAT VKDSGDYECA ARQATKEVKE 300
  301 MKTVTISVHE KGFVQIRPTF GHLETVNLHQ VREFVVEVQA YPTPRISWLK DNLTLIENLT 360
  361 EITTDVQRSQ ETRYQSKLKL IRAKEEDSGH YTIIVQNDDD MKSYTFELST LVPASILELV 420
  421 DDHHGSGGGQ TVRCTAEGTP LPNIEWMICK DIKKCNNDTS WTVLASNVSN IITEFHQRGR 480
  481 STVEGRVSFA KVEETIAVRC LAKNDLGIGN RELKLVAPSL RSELTVAAAV LVLLVIVIVS 540
  541 LIVLVVIWKQ KPRYEIRWRV IESISPDGHE YIYVDPMQLP YDSRWEFPRD GLVLGRILGS 600
  601 GAFGKVVEGT AYGLSRSQPV MKVAVKMLKP TARSSEKQAL MSELKIMTHL GPHLNIVNLL 660
  661 GACTKSGPIY IITEYCFYGD LVNYLHKNRD SFMSRHPEKP KKDLDIFGLN PADESTRSYV 720
  721 ILSFENNGDY VDMKQADTTQ YVPMLERKEV SKYSDIQRSL YDRPASYKKK SMLDSEAKNL 780
  781 LSDDDSEGLT LLDLLSFTYQ VARGMEFLAS KNCVHRDLAA RNVLLAQGKI VKICDFGLAR 840
  841 DIMHDSNYVS KGSTFLPVKW MAPESIFDNL YTTLSDVWSY GVLLWEIFSL GGTPYPGMMV 900
  901 DSTFYNKIKS GYRMAKPDHA TSEVYEIMVQ CWNSEPEKRP SFYHLSEIVE NLLPGQYKKS 960
  961 YEKIHLDFLK SDHPAVARMR VDSDNAYIGV TYKNEEDKLK EWEGGLDEQR LSADSGYIIP1020
 1021 LPDIDPVPEE EDLGKRNRHS SQTSEESAIE TGSSSSTFIK REDETIEDID MMDDIGIDSS1080
 1081 DLVEDSFL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle