Protein Overview: 5HT1B_RAT

General Information:
Name(s) found:	5HT1B_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|228717\|prf\|\|1809341A serotonin receptor 1B [NCBI NR] gi\|202543\|gb\|AAA40613.1\| serotonin receptor [NCBI NR] gi\|149019045\|gb\|EDL77686.1\| rCG26031 [Rattus norvegicus] [NCBI NR] gi\|11560016\|ref\|NP_071561.1\| 5-hydroxytryptamine (serotonin) receptor 1B [Rattus norvegicus] [NCBI NR] gi\|112815\|sp\|P28564.1\|5HT1B_RAT RecName: Full=5-hydroxytryptamine receptor 1B; Short=5-HT-1B; Short=5-HT1B; AltName: Full=Serotonin receptor 1B [NCBI NR] pir\|\|S18637 serotonin receptor 1B - rat [NCBI NR] 5-hydroxytryptamine receptor 1B OS=Rattus norvegicus GN=Htr1b PE=2 SV=1 [Swiss-Prot] (P28564) 5-hydroxytryptamine 1B receptor (5-HT-1B) (Serotonin receptor 1B) [Swiss-Prot] Ensembl_locations(Chr-bp):8-84939413 5-hydroxytryptamine 1B receptor [hmr_yeast5_DM3-1_pombe.fasta] 5-hydroxytryptamine (serotonin) receptor 1B; Serotonin (5-hydroxytryptamine (5HT)) receptor, type 1B; 5-HT1B serotonin receptor; 5-hydroxytryptamine (serotonin ) receptor 1B; Serotonin (5-hydroxytryptamine (5HT)) receptor type 1B [HMR_022704-rand.fasta] 5-hydroxytryptamine (serotonin) receptor 1B; 5-HT1B serotonin receptor; serotonin (5-hydroxytryptamine (5HT)) receptor type 1B [071204_hmrz_cont.fasta] 5-hydroxytryptamine (serotonin) receptor 1B [Rattus norvegicus]gi\|57510\|emb\|CAA44716.1\| 5-hydroxytryptamine receptor [Rattus rattus]gi\|111308\|pir\|\|S18637 serotonin receptor 1B - ratgi\|202543\|gb\|AAA40613.1\| serotonin receptorgi\|228717\|prf\|\|1809341A ser [nrdb_11152004_Chlamydomonas] Tax_Id=10116 5-hydroxytryptamine 1B receptor [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] (NM_022225) 5-hydroxytryptamine (serotonin) receptor 1B; Serotonin (5-hydroxytryptamine (5HT)) receptor, type 1B; 5-HT1B serotonin receptor [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] 5-hydroxytryptamine (serotonin) receptor 1B [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] 5-hydroxytryptamine receptor 1B (5-HT-1B) (5-HT1B) (Serotonin receptor 1B) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] rCG26031 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] serotonin receptor 1B [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] serotonin receptor [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 5-HYDROXYTRYPTAMINE 1B RECEPTOR [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] 5-hydroxytryptamine 1B receptor (5-HT-1B) (Serotonin receptor 1B) (5-HT1B) [nr-271106-contam.fasta] Tax_Id=10116 Gene_Symbol=Htr1b 5-hydroxytryptamine receptor 1B [rat-ipi-250309-contam.fasta] 5-hydroxytryptamine receptor 1B OS=Rattus norvegicus GN=Htr1b [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	386 amino acids
Gene Ontology:
Cellular Component:	integral to membrane [IEA] plasma membrane [IDA]
Biological Process:	regulation of dopamine secretion [IMP] drinking behavior [IMP] G-protein coupled receptor protein signaling pathway [IEA] signal transduction [IEA] response to cocaine [IDA] synaptic transmission [IDA] feeding behavior [IMP] negative regulation of cAMP biosynthetic process [UNKNOWN] response to toxin [UNKNOWN] response to ethanol [IMP] negative regulation of synaptic transmission, GABAergic [IMP] response to mineralocorticoid stimulus [IEP] negative regulation of synaptic transmission, glutamatergic [IMP]
Molecular Function:	serotonin binding [IDA] G-protein coupled receptor activity [IEA] protein binding [UNKNOWN][IEA] drug binding [IDA] receptor activity [IEA] serotonin receptor activity [UNKNOWN][IDA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEEQGIQCAP PPPATSQTGV PLANLSHNCS ADDYIYQDSI ALPWKVLLVA LLALITLATT  60
   61 LSNAFVIATV YRTRKLHTPA NYLIASLAVT DLLVSILVMP ISTMYTVTGR WTLGQVVCDF 120
  121 WLSSDITCCT ASIMHLCVIA LDRYWAITDA VDYSAKRTPK RAAIMIVLVW VFSISISLPP 180
  181 FFWRQAKAEE EVLDCFVNTD HVLYTVYSTV GAFYLPTLLL IALYGRIYVE ARSRILKQTP 240
  241 NKTGKRLTRA QLITDSPGST SSVTSINSRV PEVPSESGSP VYVNQVKVRV SDALLEKKKL 300
  301 MAARERKATK TLGIILGAFI VCWLPFFIIS LVMPICKDAC WFHMAIFDFF NWLGYLNSLI 360
  361 NPIIYTMSNE DFKQAFHKLI RFKCTG

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: 5HT1B_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: