Protein Overview: PP2BA_RAT

General Information:
Name(s) found:	PP2BA_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|8394030\|ref\|NP_058737.1\| protein phosphatase 3, catalytic subunit, alpha isoform [Rattus norvegicus] [NCBI NR] gi\|54038795\|sp\|P63329.1\|PP2BA_RAT RecName: Full=Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform; AltName: Full=Calmodulin-dependent calcineurin A subunit alpha isoform; AltName: Full=CAM-PRP catalytic subunit [NCBI NR] gi\|220714\|dbj\|BAA14083.1\| calcineurin A alpha [Rattus norvegicus] [NCBI NR] gi\|203495\|gb\|AAA40940.1\| calcineurin A [NCBI NR] pir\|\|A33264 phosphoprotein phosphatase (EC 3.1.3.16) 3-alpha catalytic chain - rat [NCBI NR] Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform OS=Rattus norvegicus GN=Ppp3ca PE=1 SV=1 [Swiss-Prot] (P63329) Serine/threonine protein phosphatase 2B catalytic subunit, alpha isoform (EC 3.1.3.16) (Calmodulin-dependent calcineurin A subunit, alpha isoform) (CAM-PRP catalytic subunit) [Swiss-Prot] Ensembl_locations(Chr-bp):2-228122156 Serine/threonine protein phosphatase 2B catalytic subunit, alpha isoform [hmr_yeast5_DM3-1_pombe.fasta] protein phosphatase 3, catalytic subunit, alpha isoform; Calcineurin subunit A alpha [HMR_022704-rand.fasta] protein phosphatase 3, catalytic subunit, alpha isoform [Rattus norvegicus]gi\|42415473\|ref\|NP_032939.1\| protein phosphatase 3, catalytic subunit, alpha isoform [Mus musculus]gi\|90340\|pir\|\|A31257 phosphoprotein phosphatase (EC 3.1.3.16) 3-alpha catalytic [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Splice Isoform 1 of Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] Tax_Id=10116 Serine/threonine protein phosphatase 2B catalytic subunit, alpha isoform [EBI-IPI_rat_3.13_12-01-2005_con_reversed.fasta] (NM_017041) protein phosphatase 3, catalytic subunit, alpha isoform; Calcineurin subunit A alpha [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform (Calmodulin-dependent calcineurin A subunit alpha isoform) (CAM-PRP catalytic subunit) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] protein phosphatase 3, catalytic subunit, alpha isoform [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] calcineurin A alpha [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] calcineurin A [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 SERINE/THREONINE PROTEIN PHOSPHATASE 2B CATALYTIC SUBUNIT, ALPHA ISOFORM [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=10116 Gene_Symbol=Ppp3ca Isoform 1 of Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform [rat-ipi-250309-contam.fasta] Isoform 1 of Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform OS=Rattus norvegicus GN=Ppp3ca [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	521 amino acids
Gene Ontology:
Cellular Component:	nucleus [UNKNOWN][IEA] Z disc [UNKNOWN][IEA] insoluble fraction [IDA] soluble fraction [IDA] calcineurin complex [UNKNOWN][IDA] cytoplasm [UNKNOWN][IEA] mitochondrion [UNKNOWN][IEA] membrane [IDA] microsome [UNKNOWN][IEA] cytosol [UNKNOWN][IDA]
Biological Process:	regulation of excitatory postsynaptic membrane potential [UNKNOWN][IEA] response to amphetamine [IEP] skeletal muscle fiber development [UNKNOWN][IEA] protein import into nucleus [UNKNOWN][IEA] G1/S transition of mitotic cell cycle [UNKNOWN][IEA] protein amino acid dephosphorylation [IDA] calcium ion transport [UNKNOWN][IEA] regulation of synaptic transmission [UNKNOWN][IEA] dephosphorylation [UNKNOWN] response to stress [UNKNOWN][IEA]
Molecular Function:	protein serine/threonine phosphatase activity [IDA] phosphoprotein phosphatase activity [UNKNOWN][IDA] calmodulin binding [IDA] calcium-dependent protein serine/threonine phosphatase activity [IDA] protein binding [UNKNOWN][IPI] metal ion binding [IEA] protein heterodimerization activity [IDA] hydrolase activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSEPKAIDPK LSTTDRVVKA VPFPPSHRLT AKEVFDNDGK PRVDILKAHL MKEGRLEESV  60
   61 ALRIITEGAS ILRQEKNLLD IDAPVTVCGD IHGQFFDLMK LFEVGGSPAN TRYLFLGDYV 120
  121 DRGYFSIECV LYLWALKILY PKTLFLLRGN HECRHLTEYF TFKQECKIKY SERVYDACMD 180
  181 AFDCLPLAAL MNQQFLCVHG GLSPEINTLD DIRKLDRFKE PPAYGPMCDI LWSDPLEDFG 240
  241 NEKTQEHFTH NTVRGCSYFY SYPAVCDFLQ HNNLLSILRA HEAQDAGYRM YRKSQTTGFP 300
  301 SLITIFSAPN YLDVYNNKAA VLKYENNVMN IRQFNCSPHP YWLPNFMDVF TWSLPFVGEK 360
  361 VTEMLVNVLN ICSDDELGSE EDGFDGATAA ARKEVIRNKI RAIGKMARVF SVLREESESV 420
  421 LTLKGLTPTG MLPSGVLSGG KQTLQSATVE AIEADEAIKG FSPQHKITSF EEAKGLDRIN 480
  481 ERMPPRRDAM PSDANLNSIN KALASETNGT DSNGSNSSNI Q

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Protein Overview: PP2BA_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: