Protein Overview: ARHG2_RAT

General Information:
Name(s) found:	ARHG2_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|81909626\|sp\|Q5FVC2.1\|ARHG2_RAT RecName: Full=Rho guanine nucleotide exchange factor 2; AltName: Full=Guanine nucleotide exchange factor H1; Short=GEF-H1 [NCBI NR] gi\|62643754\|ref\|XP_574974.1\| PREDICTED: rho/rac guanine nucleotide exchange factor (GEF) 2 (predicted) [Rattus norvegicus] [NCBI NR] gi\|58865728\|ref\|NP_001012079.1\| rho/rac guanine nucleotide exchange factor (GEF) 2 [Rattus norvegicus] [NCBI NR] gi\|58477218\|gb\|AAH90078.1\| Rho/rac guanine nucleotide exchange factor (GEF) 2 [Rattus norvegicus] [NCBI NR] Rho guanine nucleotide exchange factor 2 OS=Rattus norvegicus GN=Arhgef2 PE=1 SV=1 [Swiss-Prot] Ensembl_locations(Chr-bp):2-180451439 [hmr_yeast5_DM3-1_pombe.fasta] Tax_Id=10116 Rho/rac guanine nucleotide exchange factor [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] rho/rac guanine nucleotide exchange factor (GEF) 2 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Rho/rac guanine nucleotide exchange factor (GEF) 2 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 Gene_Symbol=Arhgef2 Rho guanine nucleotide exchange factor 2 [rat-ipi-250309-contam.fasta] Rho guanine nucleotide exchange factor 2 OS=Rattus norvegicus GN=Arhgef2 [011711_HMR.fasta] Rho guanine nucleotide exchange factor 2 OS=Rattus norvegicus GN=Arhgef2 PE=2 SV=1 [UNIPROT_RAT_07-21-2011_reversed.fasta]
Organism:	Rattus norvegicus
Length:	985 amino acids
Gene Ontology:
Cellular Component:	tight junction [IEA] cytoskeleton [IEA] cytoplasm [IEA] dendritic shaft [UNKNOWN][IEA] spindle [IEA] cytosol [UNKNOWN] cell junction [IEA] Golgi apparatus [IEA] neuronal cell body [UNKNOWN][IEA] intracellular [IEA] microtubule [UNKNOWN][ISS]
Biological Process:	cell division [IEA] regulation of Rho protein signal transduction [UNKNOWN][IEA] cell morphogenesis [UNKNOWN][ISS] apoptosis [UNKNOWN] actin filament organization [UNKNOWN][ISS] negative regulation of microtubule depolymerization [UNKNOWN][ISS] mitosis [IEA] induction of apoptosis by extracellular signals [UNKNOWN] cell cycle [IEA]
Molecular Function:	protein binding [UNKNOWN][IEA] metal ion binding [IEA] guanyl-nucleotide exchange factor activity [UNKNOWN][IEA] Rac GTPase binding [UNKNOWN][ISS] Rho guanyl-nucleotide exchange factor activity [UNKNOWN][IEA][ISS] Rho GTPase binding [UNKNOWN][ISS] microtubule binding [UNKNOWN][ISS] Rac guanyl-nucleotide exchange factor activity [UNKNOWN][ISS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSRIESLTRA RIDRSKEQAT KTREKEKMKE AKDARYTNGH LFTTISVSGM TMCYACNKSI  60
   61 TAKEALICPT CNVTIHNRCK DTLANCTKVK QKQQKAALLR NNTALQSVSL RSKTTTRERP 120
  121 TSAIYPSDSF RQSLLGSRRG LSSLSLAKSV STTNIAGHFN DESPLGLRQI LSQSTDSLNM 180
  181 RNRTLSVESL IDEGVEVFYN ELMSDFEMDE KDFEADSWSL AVDSSFLQQH KKEVMKKQDV 240
  241 IYELIQTELH HVRTLKIMTR LFRTGMLEEL QMEPEVVQGL FPCVDELSDI HTRFLSQLLE 300
  301 RRRQALCPGS TRNFVIHRLG DLLISQFSGS NAEQMRKTYS EFCSRHTKAL KLYKELYARD 360
  361 KRFQQFIRKM TRSAVLKRHG VQECILLVTQ RITKYPVLIN RILQNSHGIE EEYQDLAAAL 420
  421 GLVKELLSNV DQDVHELEKE ARLQEIYNRM DPRAQTPVPG KGPFGRDELL RRKLIHDGCL 480
  481 LWKTATGRFK DVLLLLMTDV LVFLQEKDQK YIFTSLDKPS VVSLQNLIVR DIANQAKGMF 540
  541 LISSGPPEMY EVHAASRDDR TTWIRVIQQS VRLCPSREDF PLIETEDKAY LRRIKTKLQQ 600
  601 KNQALVELLQ MNVELFAEMV HFQALKAGFI GMPPPTLPRG LFRLESFESL RGERLLKDAL 660
  661 REVEGLKDLL LGPCVDLPLT AREPALPVEA DSGSCPGVTA NGEARTFNGS IELCRADSDS 720
  721 SQKDRNGNQL RSPQEEALQP LVNLYGLLQG LQAVVVQQER LMEALFPEGP ERWEKLSRAN 780
  781 SRDGEAGRAA VASVTPEKQA TELALLQRQH SLLQEELRRC QRLGEERATE AGSLEARLRE 840
  841 SEQARALLER EAEEIRRQLA ALGQNEPLPA EAPWARRPLD PRRRSLPAGD ALYLSFNPPQ 900
  901 PSRGHDRLDL PVTVRSLHRP FDDREAQELG SPEDRLQDSS DPDTCSEEEV SSRLSPPHSP 960
  961 RDFTRMQDIP EETESRDGEP TASES

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.96

Protein Overview: ARHG2_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: