Protein Overview: GRM7_RAT

General Information:
Name(s) found:	GRM7_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|547904\|sp\|P35400.1\|GRM7_RAT RecName: Full=Metabotropic glutamate receptor 7; Short=mGluR7; Flags: Precursor [NCBI NR] gi\|459658\|gb\|AAA20655.1\| metabotropic glutamate receptor 7 [NCBI NR] gi\|458729\|dbj\|BAA04092.1\| metabotropic glutamate receptor [Rattus norvegicus] [NCBI NR] pir\|\|A49874 metabotropic glutamate receptor 7 - rat [NCBI NR] gi\|149036871\|gb\|EDL91489.1\| rCG56083, isoform CRA_c [Rattus norvegicus] [NCBI NR] gi\|13591963\|ref\|NP_112302.1\| glutamate receptor, metabotropic 7 [Rattus norvegicus] [NCBI NR] Metabotropic glutamate receptor 7 precursor (mGluR7) - Rattus norvegicus (Rat) [Swiss-Prot] Metabotropic glutamate receptor 7 OS=Rattus norvegicus GN=Grm7 PE=1 SV=1 [Swiss-Prot] Ensembl_locations(Chr-bp):4-152427255 Metabotropic glutamate receptor 7 precursor [hmr_yeast5_DM3-1_pombe.fasta] metabotropic glutamate receptor mGluR7 [HMR_022704-rand.fasta] glutamate receptor, metabotropic 7 [Rattus norvegicus]gi\|2143844\|pir\|\|A49874 metabotropic glutamate receptor 7 - ratgi\|458729\|dbj\|BAA04092.1\| metabotropic glutamate receptor mGluR7 [Rattus norvegicus]gi\|547904\|sp\|P35400\|MGR7_RAT Metabotropic glutamate [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Metabotropic glutamate receptor 7 precursor [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] (NM_031040) metabotropic glutamate receptor mGluR7 [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] Metabotropic glutamate receptor 7 precursor (mGluR7) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] glutamate receptor, metabotropic 7 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] rCG56083, isoform CRA_c [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] metabotropic glutamate receptor [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] metabotropic glutamate receptor 7 [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 METABOTROPIC GLUTAMATE RECEPTOR 7 PRECURSOR [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=10116 Gene_Symbol=Grm7 Metabotropic glutamate receptor 7 [rat-ipi-250309-contam.fasta] Metabotropic glutamate receptor 7 OS=Rattus norvegicus GN=Grm7 [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	915 amino acids
Gene Ontology:
Cellular Component:	presynaptic membrane [IDA] rough endoplasmic reticulum [IDA] Golgi apparatus [IDA] neuronal cell body [IDA] protein complex [IDA] synapse [IDA] plasma membrane [IEA] axon terminus [IDA] cell surface [IDA] membrane fraction [IDA] dendrite [UNKNOWN][IDA] presynaptic active zone [IDA] terminal button [IDA] postsynaptic membrane [IDA] cell cortex [UNKNOWN] dendritic shaft [IDA] integral to membrane [UNKNOWN][IEA] asymmetric synapse [IDA] axon [IDA]
Biological Process:	negative regulation of adenylate cyclase activity [UNKNOWN] G-protein coupled receptor protein signaling pathway [IEA] signal transduction [IEA] inhibition of adenylate cyclase activity by metabotropic glutamate receptor signaling pathway [IDA] synaptic transmission [UNKNOWN] negative regulation of glutamate secretion [IDA] negative regulation of cAMP biosynthetic process [UNKNOWN] associative learning [UNKNOWN] memory [UNKNOWN] conditioned taste aversion [UNKNOWN] behavioral fear response [UNKNOWN] learning or memory [TAS] sensory perception of sound [UNKNOWN] short-term memory [UNKNOWN] sensory perception of smell [IEA] multicellular organismal response to stress [UNKNOWN] transmission of nerve impulse [UNKNOWN] neurological system process [UNKNOWN] adult behavior [UNKNOWN] response to stimulus [IEA]
Molecular Function:	group III metabotropic glutamate receptor activity [UNKNOWN][IDA][TAS] serine binding [UNKNOWN] calmodulin binding [IPI] protein homodimerization activity [IDA] glutamate receptor activity [UNKNOWN] calcium ion binding [UNKNOWN] PDZ domain binding [IPI] adenylate cyclase inhibitor activity [UNKNOWN] glutamate binding [UNKNOWN][IDA] receptor activity [IEA] calcium channel regulator activity [UNKNOWN] adenylate cyclase inhibiting metabotropic glutamate receptor activity [IDA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVQLGKLLRV LTLMKFPCCV LEVLLCVLAA AARGQEMYAP HSIRIEGDVT LGGLFPVHAK  60
   61 GPSGVPCGDI KRENGIHRLE AMLYALDQIN SDPNLLPNVT LGARILDTCS RDTYALEQSL 120
  121 TFVQALIQKD TSDVRCTNGE PPVFVKPEKV VGVIGASGSS VSIMVANILR LFQIPQISYA 180
  181 STAPELSDDR RYDFFSRVVP PDSFQAQAMV DIVKALGWNY VSTLASEGSY GEKGVESFTQ 240
  241 ISKEAGGLCI AQSVRIPQER KDRTIDFDRI IKQLLDTPNS RAVVIFANDE DIKQILAAAK 300
  301 RADQVGHFLW VGSDSWGSKI NPLHQHEDIA EGAITIQPKR ATVEGFDAYF TSRTLENNRR 360
  361 NVWFAEYWEE NFNCKLTISG SKKEDTDRKC TGQERIGKDS NYEQEGKVQF VIDAVYAMAH 420
  421 ALHHMNKDLC ADYRGVCPEM EQAGGKKLLK YIRHVNFNGS AGTPVMFNKN GDAPGRYDIF 480
  481 QYQTTNTTNP GYRLIGQWTD ELQLNIEDMQ WGKGVREIPS SVCTLPCKPG QRKKTQKGTP 540
  541 CCWTCEPCDG YQYQFDEMTC QHCPYDQRPN ENRTGCQNIP IIKLEWHSPW AVIPVFLAML 600
  601 GIIATIFVMA TFIRYNDTPI VRASGRELSY VLLTGIFLCY IITFLMIAKP DVAVCSFRRV 660
  661 FLGLGMCISY AALLTKTNRI YRIFEQGKKS VTAPRLISPT SQLAITSSLI SVQLLGVFIW 720
  721 FGVDPPNIII DYDEHKTMNP EQARGVLKCD ITDLQIICSL GYSILLMVTC TVYAIKTRGV 780
  781 PENFNEAKPI GFTMYTTCIV WLAFIPIFFG TAQSAEKLYI QTTTLTISMN LSASVALGML 840
  841 YMPKVYIIIF HPELNVQKRK RSFKAVVTAA TMSSRLSHKP SDRPNGEAKT ELCENVDPNS 900
  901 PAAKKKYVSY NNLVI

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: GRM7_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: