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Protein Overview: APOA2_RAT

General Information:
Name(s) found: APOA2_RAT [Swiss-Prot]
Description(s) found:
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  • pir||A24846 apolipoprotein A-II precursor - rat [NCBI NR]
  • gi|6978517|ref|NP_037244.1| apolipoprotein A-II [Rattus norvegicus] [NCBI NR]
  • gi|55749|emb|CAA27185.1| unnamed protein product [Rattus norvegicus] [NCBI NR]
  • gi|149040654|gb|EDL94611.1| apolipoprotein A-II, isoform CRA_a [Rattus norvegicus] [NCBI NR]
  • gi|149040653|gb|EDL94610.1| apolipoprotein A-II, isoform CRA_a [Rattus norvegicus] [NCBI NR]
  • gi|114004|sp|P04638.1|APOA2_RAT RecName: Full=Apolipoprotein A-II; Short=Apo-AII; Short=ApoA-II; Flags: Precursor [NCBI NR]
  • Apolipoprotein A-II OS=Rattus norvegicus GN=Apoa2 PE=2 SV=1 [Swiss-Prot]
  • (P04638) Apolipoprotein A-II precursor (Apo-AII) [Swiss-Prot]
  • Ensembl_locations(Chr-bp):13-78067814 Apolipoprotein A-II precursor [hmr_yeast5_DM3-1_pombe.fasta]
  • apolipoprotein A-II [HMR_022704-rand.fasta]
  • apolipoprotein A-II [Rattus norvegicus]gi|55749|emb|CAA27185.1| unnamed protein product [Rattus norvegicus]gi|114004|sp|P04638|APA2_RAT Apolipoprotein A-II precursor (Apo-AII)gi|91985|pir||A24846 apolipoprotein A-II precursor - rat [nrdb_11152004_Chlamydomonas]
  • Tax_Id=10116 Apolipoprotein A-II precursor [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta]
  • (NM_013112) apolipoprotein A-II [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta]
  • Apolipoprotein A-II precursor (Apo-AII) (ApoA-II) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • apolipoprotein A-II [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • apolipoprotein A-II, isoform CRA_a [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • unnamed protein product [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • Tax_Id=10116 APOLIPOPROTEIN A-II PRECURSOR [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta]
  • Tax_Id=10116 Gene_Symbol=Apoa2 Apolipoprotein A-II [rat-ipi-250309-contam.fasta]
  • apolipoprotein A-II precursor [Rattus norvegicus] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta]
  • Apolipoprotein A-II OS=Rattus norvegicus GN=Apoa2 [011711_HMR.fasta]
    • Organism: Rattus norvegicus
    Length: 102 amino acids

    Gene Ontology:
    Cellular Component: very-low-density lipoprotein particle [UNKNOWN][IEA]
    endoplasmic reticulum lumen [UNKNOWN]
    extracellular space [UNKNOWN][IEA]
    chylomicron [UNKNOWN][IEA]
    high-density lipoprotein particle [UNKNOWN]
    spherical high-density lipoprotein particle [UNKNOWN][IEA]
    extracellular region [UNKNOWN][IEA]
    cellular_component [ND]
    Biological Process: triglyceride-rich lipoprotein particle remodeling [UNKNOWN][IEA]
    response to estrogen stimulus [IEP]
    high-density lipoprotein particle remodeling [UNKNOWN][IEA]
    low-density lipoprotein particle remodeling [UNKNOWN][IEA]
    phospholipid catabolic process [UNKNOWN][IEA]
    cholesterol metabolic process [UNKNOWN][IEA]
    lipoprotein metabolic process [UNKNOWN][IEA]
    cholesterol homeostasis [UNKNOWN][IEA]
    negative regulation of cholesterol import [UNKNOWN][IEA]
    negative regulation of cytokine secretion during immune response [UNKNOWN][IEA]
    diacylglycerol catabolic process [UNKNOWN][IEA]
    response to glucose stimulus [UNKNOWN][IEA]
    reverse cholesterol transport [UNKNOWN][IEA]
    response to glucocorticoid stimulus [IEP]
    negative regulation of lipase activity [UNKNOWN][IEA]
    cholesterol transport [IDA]
    regulation of intestinal cholesterol absorption [UNKNOWN][IEA]
    positive regulation of cholesterol esterification [UNKNOWN][IEA]
    negative regulation of lipid catabolic process [UNKNOWN][IEA]
    positive regulation of lipid catabolic process [UNKNOWN][IEA]
    negative regulation of cholesterol transporter activity [UNKNOWN][IEA]
    high-density lipoprotein particle assembly [UNKNOWN][IEA]
    high-density lipoprotein particle clearance [UNKNOWN][IEA]
    protein folding [UNKNOWN][IEA]
    positive regulation of interleukin-8 biosynthetic process [UNKNOWN][ISS]
    phosphatidylcholine biosynthetic process [UNKNOWN][IEA]
    lipid transport [UNKNOWN][IEA]
    regulation of protein stability [UNKNOWN][IEA]
    acute inflammatory response [IEP]
    negative regulation of very-low-density lipoprotein particle remodeling [UNKNOWN][IEA]
    response to drug [IEP]
    negative regulation of cholesterol transport [UNKNOWN]
    cholesterol efflux [UNKNOWN][IEA]
    organ regeneration [IDA]
    phospholipid efflux [UNKNOWN][IEA]
    Molecular Function: protein homodimerization activity [UNKNOWN][IEA]
    cholesterol binding [UNKNOWN][IEA]
    phosphatidylcholine-sterol O-acyltransferase activator activity [UNKNOWN][IEA]
    lipid binding [UNKNOWN][IEA]
    high-density lipoprotein binding [UNKNOWN][IEA]
    phospholipid binding [UNKNOWN]
    molecular_function [ND]
    apolipoprotein receptor binding [UNKNOWN][IEA]
    protein binding [UNKNOWN][IEA]
    lipid transporter activity [UNKNOWN][IEA]
    protein heterodimerization activity [UNKNOWN][ISS]
    lipase inhibitor activity [UNKNOWN][IEA]
    phosphatidylcholine binding [UNKNOWN][IEA]
    high-density lipoprotein receptor binding [UNKNOWN][IEA]
    cholesterol transporter activity [UNKNOWN][IDA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKLLAMVALL VTICSLEGAL VRRQAAETDV QTLFSQYLQS LTDYGKDLME KAQPSEIQNQ  60
   61 AKAYFQNAQE RLTPFVQRTG TNLMDFLSRL MSPEEKPAPA AK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..102] PSI-BLAST 31.30103 Apolipoprotein A-II


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle