Protein Overview: gi|119352249

General Information:
Name(s) found:	gi\|119352249 [NCBI NR]
Description(s) found:	gi\|119352249\|gb\|ABL63812.1\| polyadenylate-binding protein [Plasmodium falciparum] [NCBI NR]
Organism:	Plasmodium falciparum
Length:	875 amino acids
Gene Ontology:
Cellular Component:	cellular_component [ND]
Biological Process:	RNA processing [ISS]
Molecular Function:	poly(A) RNA binding [ISS] mRNA binding [ISS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIATGTNMMH PSFSTASLYV GDLNEDVTEA VLYEIFNTVG HVSSIRVCRD SVTRKSLGYA  60
   61 YVNYHNLADA ERALDTLNYT NIKGQPARLM WSHRDPSLRK SGTGNIFVKN LDKSIDNKAL 120
  121 FDTFSMFGNI LSCKVATDEF GKSKSYGFVH YEDEESAKEA IEKVNGVQLG SKNVYVGPFI 180
  181 KKSERATNDT KFTNLYVKNF PDSVTETHLR QLFNPYGEIT SMIVKMDNKN RKFCFINYAD 240
  241 AESAKNAMDN LNGKKITDDG QIDETYDPKK EEATASTSGA ANQTTGTDAD KTDKNDKNNK 300
  301 ADKNEKGDSS NANNNATATG ATTTDTTTTP GETTTTTANA DSTGANNNNG LSPNTNTSNT 360
  361 TTGSSNNSIN LNENNNTAGN NNSTNNNNNS GSSMNNAGSA KKDETAASDC ADTPNILYVG 420
  421 PHQSRARRHA ILKAKFDNLN VENKNKHQGV NLYIKNLDDG IDDIMLRELF EPFGTITSAK 480
  481 VMRDEKEQSK GFGFVCFASQ EEANKAVTEM HLKIINGKPL YVGLAEKREQ RLSRLQQRFR 540
  541 MHPIRHHMNN PLNTPMQYAS PQSPQLQFSQ NTLSYGRPVI TAFNQNNLIS WRHQQAAQQQ 600
  601 AVHQQAVHQQ AAQQQLNFNT NLRGQINQMR LYTQNNMMNN NLNQNKPNAQ LHHNQQYVPN 660
  661 ALAQNGQQQP NLNAAGQHNA QQLQQQGNNQ LLNNNMRNMN NRANRNMGNL GNMNNQKQLP 720
  721 LNINNKQQNA ASQANQMNHQ AQPQGAQAQQ KNPQQMQQVP QGNNFKFTAQ ARNRMELPNK 780
  781 NANKVNTMNN NMNVNFNNNS TLTAAALASA PPSMQKQVLG ENLFPLVANY HPTLAGKITG 840
  841 MMLEMDNSEL LILLENEEQL KKKIDEALVV LQKAK

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Microscopy / Localization Data

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No microscopy data found in the PDR for this protein.

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..190]	PSI-BLAST	59.045757	Poly(A)-binding protein
2	View Details	[191..338]	PSI-BLAST	5.39794	NMR Structure of RRM2 from Human Polypyrimidine Tract Binding Protein Isoform 1 (PTB1)
3	View Details	[339..439]	deduced	N/A	No confident structure predictions are available.
4	View Details	[440..525]	PSI-BLAST	23.0	No description for 2d9pA was found.
5	View Details	[526..617]	deduced	N/A	No confident structure predictions are available.
6	View Details	[618..746]	PSI-BLAST	6.69897	Sec24
7	View Details	[747..875]	PSI-BLAST	35.0	poly(A) binding protein

Functions predicted (by domain):

#

Gene Ontology predictions

1

Term	Confidence	Notes
RNA binding	5.15097136329571	bayes_pls_golite062009
nucleic acid binding	4.92126426323641	bayes_pls_golite062009
mRNA binding	4.05281507540116	bayes_pls_golite062009
binding	3.64400841800969	bayes_pls_golite062009
	2.24263873726102	bayes_pls_golite062009
transcription regulator activity	2.18211199677674	bayes_pls_golite062009
DNA binding	1.98418556946403	bayes_pls_golite062009
single-stranded RNA binding	1.46469774223879	bayes_pls_golite062009
protein binding	1.12215421354121	bayes_pls_golite062009
transcription factor activity	1.07843408116687	bayes_pls_golite062009
poly-pyrimidine tract binding	1.04854882388951	bayes_pls_golite062009
mRNA 3'-UTR binding	0.824614388276642	bayes_pls_golite062009
sequence-specific DNA binding	0.383589644462932	bayes_pls_golite062009

2

Term	Confidence	Notes
RNA binding	5.15097136329571	bayes_pls_golite062009
nucleic acid binding	4.92126426323641	bayes_pls_golite062009
mRNA binding	4.05281507540116	bayes_pls_golite062009
binding	3.64400841800969	bayes_pls_golite062009
	2.24263873726102	bayes_pls_golite062009
transcription regulator activity	2.18211199677674	bayes_pls_golite062009
DNA binding	1.98418556946403	bayes_pls_golite062009
single-stranded RNA binding	1.46469774223879	bayes_pls_golite062009
protein binding	1.12215421354121	bayes_pls_golite062009
transcription factor activity	1.07843408116687	bayes_pls_golite062009
poly-pyrimidine tract binding	1.04854882388951	bayes_pls_golite062009
mRNA 3'-UTR binding	0.824614388276642	bayes_pls_golite062009
sequence-specific DNA binding	0.383589644462932	bayes_pls_golite062009

3

No functions predicted.

4

No functions predicted.

5

No functions predicted.

6

No functions predicted.

7

Term	Confidence	Notes
RNA binding	4.11788426448287	bayes_pls_golite062009
mRNA binding	4.06818972936809	bayes_pls_golite062009
nucleic acid binding	3.78909647605682	bayes_pls_golite062009
eukaryotic initiation factor 4G binding	3.4111148675327	bayes_pls_golite062009
single-stranded RNA binding	3.03728178586535	bayes_pls_golite062009
binding	2.76167454154417	bayes_pls_golite062009
poly(A) RNA binding	2.66269581586161	bayes_pls_golite062009
poly-purine tract binding	2.60937924017999	bayes_pls_golite062009
protein binding	0.856075580719879	bayes_pls_golite062009
catalytic activity	0.287695754348243	bayes_pls_golite062009

Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

Philius Transmembrane Prediction:

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Source: Reynolds et al. (2008)

YRC Informatics Platform - Version 3.0
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