Protein Overview: PTH1R_RAT

General Information:
Name(s) found:	PTH1R_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|9910336\|ref\|NP_064458.1\| parathyroid hormone receptor 1 [Rattus norvegicus] [NCBI NR] gi\|467317\|gb\|AAA68098.1\| parathyroid hormone/parathyroid hormone related-peptide receptor [NCBI NR] pir\|\|I54195 parathyroid hormone/parathyroid hormone related-peptide receptor - rat [NCBI NR] gi\|206035\|gb\|AAA41811.1\| parathyroid hormone receptor [NCBI NR] gi\|149018421\|gb\|EDL77062.1\| parathyroid hormone receptor 1, isoform CRA_b [Rattus norvegicus] [NCBI NR] gi\|131572\|sp\|P25961.1\|PTH1R_RAT RecName: Full=Parathyroid hormone/parathyroid hormone-related peptide receptor; AltName: Full=Parathyroid hormone 1 receptor; Short=PTH1 receptor; AltName: Full=PTH/PTHrP type I receptor; Short=PTH/PTHr receptor; Flags: Pre [NCBI NR] (P25961) Parathyroid hormone/parathyroid hormone-related peptide receptor precursor (PTH/PTHr receptor) (PTH/PTHrP type I receptor) [Swiss-Prot] Parathyroid hormone/parathyroid hormone-related peptide receptor OS=Rattus norvegicus GN=Pthr1 PE=2 SV=1 [Swiss-Prot] Parathyroid hormone/parathyroid hormone-related peptide receptor OS=Rattus norvegicus GN=Pth1r PE=2 SV=1 [Swiss-Prot] Ensembl_locations(Chr-bp):8-119122703 Parathyroid hormone/parathyroid hormone-related peptide receptor precursor [hmr_yeast5_DM3-1_pombe.fasta] parathyroid hormone receptor 1; parathyroid hormone/parathyroid hormone-related peptide receptor [HMR_022704-rand.fasta] parathyroid hormone receptor 1 [Rattus norvegicus]gi\|2143899\|pir\|\|I54195 parathyroid hormone/parathyroid hormone related-peptide receptor - ratgi\|467317\|gb\|AAA68098.1\| parathyroid hormone/parathyroid hormone related-peptide receptorgi\|131572\|sp\|P25961\| [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Parathyroid hormone/parathyroid hormone-related peptide receptor precursor [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] (NM_020073) parathyroid hormone receptor [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] parathyroid hormone receptor 1 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Parathyroid hormone/parathyroid hormone-related peptide receptor precursor (PTH/PTHrP type I receptor) (PTH/PTHr receptor) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] parathyroid hormone receptor 1, isoform CRA_b [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] parathyroid hormone/parathyroid hormone related-peptide receptor [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] parathyroid hormone receptor [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 PARATHYROID HORMONE/PARATHYROID HORMONE-RELATED PEPTIDE RECEPTOR PRECURSOR [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Parathyroid hormone/parathyroid hormone-related peptide receptor precursor (PTH/PTHr receptor) (PTH/PTHrP type I receptor) [nr-271106-contam.fasta] Tax_Id=10116 Gene_Symbol=Pthr1 Parathyroid hormone/parathyroid hormone-related peptide receptor [rat-ipi-250309-contam.fasta] parathyroid hormone receptor 1 precursor [Rattus norvegicus] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta] Parathyroid hormone/parathyroid hormone-related peptide receptor OS=Rattus norvegicus GN=Pth1r [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	591 amino acids
Gene Ontology:
Cellular Component:	nucleus [IDA] brush border membrane [IDA] cytoplasm [IDA] integral to membrane [IEA] basolateral plasma membrane [IDA] intracellular [UNKNOWN][IEA] plasma membrane [IEA]
Biological Process:	bone mineralization [UNKNOWN][IEA] signal transduction [IEA] negative regulation of cell proliferation [UNKNOWN][IEA] positive regulation of cell proliferation [UNKNOWN][IEA] chondrocyte differentiation [UNKNOWN][IEA] cell maturation [UNKNOWN][IEA] osteoblast development [UNKNOWN][IEA] activation of adenylate cyclase activity by G-protein signaling pathway [UNKNOWN][IEA] activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger [UNKNOWN][IEA] aging [IEP] cellular calcium ion homeostasis [UNKNOWN][IEA] elevation of cytosolic calcium ion concentration [IDA] skeletal system development [UNKNOWN][IEA] ossification [UNKNOWN] bone resorption [UNKNOWN][IEA]
Molecular Function:	parathyroid hormone receptor activity [UNKNOWN][IDA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGAARIAPSL ALLLCCPVLS SAYALVDADD VFTKEEQIFL LHRAQAQCDK LLKEVLHTAA  60
   61 NIMESDKGWT PASTSGKPRK EKASGKFYPE SKENKDVPTG SRRRGRPCLP EWDNIVCWPL 120
  121 GAPGEVVAVP CPDYIYDFNH KGHAYRRCDR NGSWEVVPGH NRTWANYSEC LKFMTNETRE 180
  181 REVFDRLGMI YTVGYSMSLA SLTVAVLILA YFRRLHCTRN YIHMHMFLSF MLRAASIFVK 240
  241 DAVLYSGFTL DEAERLTEEE LHIIAQVPPP PAAAAVGYAG CRVAVTFFLY FLATNYYWIL 300
  301 VEGLYLHSLI FMAFFSEKKY LWGFTIFGWG LPAVFVAVWV GVRATLANTG CWDLSSGHKK 360
  361 WIIQVPILAS VVLNFILFIN IIRVLATKLR ETNAGRCDTR QQYRKLLRST LVLVPLFGVH 420
  421 YTVFMALPYT EVSGTLWQIQ MHYEMLFNSF QGFFVAIIYC FCNGEVQAEI RKSWSRWTLA 480
  481 LDFKRKARSG SSSYSYGPMV SHTSVTNVGP RAGLSLPLSP RLPPATTNGH SQLPGHAKPG 540
  541 APATETETLP VTMAVPKDDG FLNGSCSGLD EEASGSARPP PLLQEEWETV M

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: PTH1R_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: